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Breast Cancer clinical trials

View clinical trials related to Breast Cancer.

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NCT ID: NCT03193008 Active, not recruiting - Breast Cancer Clinical Trials

Current Value of Axillary Ultrasound in the Staging of Breast Cancer. Is BSGC Still Necessary?

Start date: April 1, 2017
Phase: N/A
Study type: Observational

AUS/FNAC allows the identification of tumors without axillary tumor involvement, or with low axillary tumor burden, many of which do not benefit from SLNB, in the staging of early breast cancer. Objective: To calculate the negative predictive value of AUS/FNAC in those patients with breast cancer who meet ACOSOG Z0011 criteria.

NCT ID: NCT03123263 Active, not recruiting - Breast Cancer Clinical Trials

Echocardiographic Changes During Adjuvant Therapy in Hispanic Women With Her-2 Neu Expressing Breast Cancer

Start date: April 11, 2017
Phase: N/A
Study type: Observational

This study retrospectively looks at changes in Echocardiographic parameters while using transtuzumab

NCT ID: NCT03113019 Active, not recruiting - Breast Cancer Clinical Trials

Autologous Antigen-activated Dendritic Cells in the Treatment of Patients With Breast Cancer

BC-LDC
Start date: February 11, 2014
Phase: Early Phase 1
Study type: Interventional

The purpose of this work: to assess the tolerability and effectiveness of the autogemotherapy method on the basis of autologous antigen-activated dendritic cells in the treatment of patients with breast cancer. This technology is intended for complex treatment of patients with breast cancer and is aimed at preventing the occurrence and treatment of secondary foci. The need for this technology is justified by the widespread occurrence of breast cancer among women, a decrease in the average age at onset of the disease and a young age, and the chemoresistantness of locally advanced forms of cancer.

NCT ID: NCT03076190 Active, not recruiting - Breast Cancer Clinical Trials

My Surgical Success: A Randomized Controlled Pilot Study of a Pre-surgical Psychological Intervention

Start date: August 2015
Phase: N/A
Study type: Interventional

The primary purpose of this study is to determine the feasibility and preliminary efficacy of a remote, Internet-based, pre-surgical psychoeducational intervention delivered to patients scheduled for breast cancer surgery (compared to an active control group that receives health education). Aim 1: Determine feasibility, satisfaction, and perceived utility of My Surgical Success. Hypothesis 1: For My Surgical Success, the investigators anticipate 50% engagement in the study (feasibility). Of those who complete My Surgical Success we expect 80% satisfaction ratings, and 80% perceived utility of the information learned. Aim 2: Determine group differences in within-subject pain catastrophizing scores (baseline - 0 to 48 hours before surgery). Hypothesis 2: My Surgical Success participants evidence greater reduction in pain catastrophizing (measured with the Pain Catastrophizing Scale; PCS) compared to the HE Control group. Aim 3: Determine group differences in time to post-surgical pain and opioid cessation. Hypothesis 3: My Surgical Success participants will evidence quicker time to post-surgical pain and opioid cessation compared to the HE Control Group. Aim 4: Determine group differences in post-surgical psychological correlates (PROMIS Depression, Anxiety, Function, Pain Interference, Sleep Disturbance, Sleep Related Impairment, Anger, Fatigue, Global, Distress, and Pain Intensity). Hypothesis 4: My Surgical Success participants will evidence greater post-surgical function and lower pain related interference compared to the HE Control Group. The goal of this research is to advance our understanding regarding the feasibility and effectiveness of remote psychoeducation interventions and impact on post-surgical outcomes.

NCT ID: NCT02926547 Active, not recruiting - Breast Cancer Clinical Trials

New Approaches for the Identification and Characterization of Functional Markers of the Risk of Extension of Breast Cancer Without Lymph Node Involvement

Start date: March 2014
Phase: N/A
Study type: Observational

1. Identify the tissue proteins associated with early breast cancer invasion phases without lymph node involvement . 2. Consider their role in the invasion and the risk of tumor spread .

NCT ID: NCT02921191 Active, not recruiting - Breast Cancer Clinical Trials

Descriptive Analysis of G-CSF Use in Patients With Breast Cancer, Lung Cancer, or Lymphoma Treated

Start date: January 2008
Phase: N/A
Study type: Observational

Purpose: With the existing recombinant human granulocyte colony-stimulating factors (G-CSFs) patents expiring and the FDA approval of new biosimilar and innovator biologics, patients being treated with Grade III and IV myelosuppressive chemotherapy regimens will have additional therapeutic options. This observational study will describe the patient characteristics of new users of G-CSFs. It will describe in the treatment cohorts a primary outcome of hospitalizations for febrile neutropenia. The BBCIC will use the findings from this descriptive analysis to design a comparative study evaluating the real-world effectiveness and safety of biosimilar and innovator G-CSFs.

NCT ID: NCT02902991 Active, not recruiting - Breast Cancer Clinical Trials

The Study on the Clinical Utility of Liquid Biopsy in Breast Cancer

Start date: June 2016
Phase: N/A
Study type: Observational

Through this prospective clinical trial,the investigators will focus on the relationship between circulating tumor biomarkers (i.e. circulating tumor cells, circulating tumor DNA and other biomarkers) and the status of primary tumor to discuss its application for assessing prognosis and individualized therapeutic direction. Moreover, the relationship between the circulating tumor cell subpopulations based on epithelial-mesenchymal transition and molecular pathological classification of breast cancer will be determined, which may enable the determination of the value of its application in therapeutic decision making.

NCT ID: NCT02893761 Active, not recruiting - Breast Cancer Clinical Trials

Bergonie Institute Breast Cancer Database

Start date: January 1990
Phase: N/A
Study type: Observational

A database of breast cancer patients was established at Institute Bergonié since the 90s , to assess patients' survival, assess practice, search for prognostic factors.

NCT ID: NCT02883985 Active, not recruiting - Breast Cancer Clinical Trials

Safety Study of the Hypo-fractionated (Large Doses) Radiation Therapy in Post-menopausal Women With Breast Cancers

Start date: May 2000
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine whether high dose of radiation therapy (RT) are effective over standard 6-week radiation treatment in patients with breast cancer

NCT ID: NCT02878057 Active, not recruiting - Breast Cancer Clinical Trials

Multicenter Phase II Study of Apatinib in Patients With Advanced Breast Cancer

Start date: May 2016
Phase: Phase 2
Study type: Interventional

The treatment of the patients with recurrent and metastatic breast cancer remains a major problem. There is still a lack of effective targeted therapy for Her-2 negative breast cancer.Based on the present researches on the anti-angiogenesis drugs in advanced breast cancer, the investigators believe that it is necessary to further explore the efficacy and safety of apatinib in advanced breast cancer.