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Breast Cancer clinical trials

View clinical trials related to Breast Cancer.

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NCT ID: NCT05389605 Completed - Breast Cancer Clinical Trials

Outcomes of Local Perforator Flaps in Oncoplastic Surgery

Start date: April 18, 2020
Phase:
Study type: Observational

This is a single center experience of using local perforator flaps in partial breast reconstruction for breast tumors while evaluating cosmetic outcomes, patient satisfaction and well-being using a validated self-administered questionnaire.

NCT ID: NCT05388734 Recruiting - Breast Cancer Clinical Trials

Shared Decision Making on Care Pathways and CAMs: A Pilot Study

Start date: September 28, 2022
Phase: N/A
Study type: Interventional

Shared Decision Making on Care Pathways and alternative and complementary medicine (CAMs) : A Pilot Study. Study whose aim is to evaluate the feasibility of a study proposing a therapeutic education consultation leaning on the usual care pathway by estimating the recruitment capacity over 4 months as well as the acceptance rate of the study among patients diagnosed with breast cancer.

NCT ID: NCT05388149 Recruiting - Breast Cancer Clinical Trials

Kadcyla And Neratinib for Interception of HER2+ Breast Cancer With Molecular Residual Disease

Start date: December 6, 2022
Phase: Phase 2
Study type: Interventional

This is a Phase 2 study for patients with resected Stage I-III HER2+ breast cancer with detected molecular residual disease (MRD+) following standard neoadjuvant and locoregional therapy delivered with curative intent. In this study Patients will be treated with neratinib in addition to their standard T-DM1 adjuvant therapy. Neratinib will be administered orally at a dose of 160 mg daily for up to 12 months, or until the time of clinical recurrence, discontinuation due to toxicity, or withdrawal of consent. This study will have two stages, stage 1 would enroll up to 8 participants to clear the Minimal Residual Disease (MRD) and Stage 2 will enroll up to 5 participants. The purpose of this study is to determine if this study population would have a better outcome from adding neratinib to their standard T-DM1 adjuvant therapy.

NCT ID: NCT05386719 Recruiting - Breast Cancer Clinical Trials

Cardiometabolic Screening Program

Start date: June 3, 2022
Phase: N/A
Study type: Interventional

This research study is being done to implement a screening program for prediabetes, diabetes, dyslipidemia and/or hyperlipidemia, and higher risk of cardiovascular disease in breast cancer survivors. This program will also help to direct individuals with risk factors to community and institutional resources for management.

NCT ID: NCT05386641 Not yet recruiting - Clinical trials for Breast Cancer Survivors

Risk Factors for Shoulder Joint Motion Restriction

Start date: August 15, 2022
Phase:
Study type: Observational

In breast cancer patients, limitation of shoulder joint movement may occur following cancer treatment. Shoulder limitation causes a significant decrease in the patient's participation in activities of daily living. The aim of the study is to define these limitations, to evaluate in detail all the structures that cause the problem, and to determine the causes of the limitations in patients with shoulder joint movement limitation developed after breast cancer survivors.

NCT ID: NCT05386628 Not yet recruiting - Clinical trials for Breast Cancer Survivors

The Effect of Myofascial Chain Release Techniques on Shoulder Joint Range of Motion in Breast Cancer Survivors

Start date: August 15, 2022
Phase: N/A
Study type: Interventional

In breast cancer patients, limitation of shoulder joint movement occurs following mastectomy surgery. Studies have reported that damage to the fascia on the pectoralis major muscle during mastectomy surgery contributes to the development of the limitation. The aim of this study is to investigate the effect of release techniques applied to the fascia on the pectoralis major muscle and the fascial chain on the incerasing of shoulder joint range of motion.

NCT ID: NCT05386524 Recruiting - Breast Cancer Clinical Trials

Sintilimab and Bevacizumab Biosimilar Combined With PLD in mTNBC

Start date: June 15, 2022
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy and safety of sintilimab and bevacizumab biosimilar combined with pegylated liposomal doxorubicin in pretreated metastatic triple-negative breast cancer

NCT ID: NCT05386511 Completed - Breast Cancer Clinical Trials

Real-world Study of UTD1 in Chinese Advanced Breast Cancer

Start date: April 1, 2022
Phase:
Study type: Observational

To evaluate the efficacy and safety of UTD1 in patients with advanced breast cancer.

NCT ID: NCT05385146 Completed - Breast Cancer Clinical Trials

Effect of Chan-Chuang Qigong With Breathing Meditation on Quality of Life in Patients With Breast Cancer

Start date: December 25, 2017
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the effect of the 15 weeks Chan-Chuang qigong program with breathing meditation on quality of life and interoceptive awareness in patients with breast cancer during chemotherapy.

NCT ID: NCT05384119 Completed - Breast Cancer Clinical Trials

Phase 1b/2 Study of TTI-101 in Combination for Patients With Metastatic Hormone Receptor-Positive and HER2-Negative Breast Cancer

Start date: January 9, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The primary objective of Phase 1b will be to evaluate the safety and tolerability of TTI-101 when added to palbociclib and AI or fulvestrant administered orally to participants with hormone receptor-positive (HR+) human epidermal receptor 2-negative (HER2)- palbociclib-resistant breast cancer, and to determine the recommended Phase 2 dose (RP2D) for TTI-101 when added to palbociclib and AI or fulvestrant. The primary objective of Phase 2 will be to evaluate anti-tumor activity in participants who receive TTI-101 added to palbociclib or ribociclib and AI or fulvestrant.