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Breast Cancer clinical trials

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NCT ID: NCT05608252 Recruiting - Breast Cancer Clinical Trials

VS-6766+Abema+Fulv in Met HR+/HER- BC

Start date: February 23, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This research is being done to evaluate the safety and effectiveness of a drug currently known as VS-6766 in combination with the drugs abemaciclib and fulvestrant in HR+/HER2-negative breast cancer. The names of the study drugs involved in this study are: - VS-6766 - Abemaciclib - Fulvestrant

NCT ID: NCT05607849 Not yet recruiting - Breast Cancer Clinical Trials

Breast Cancer Screening Uptake: a Randomized Controlled Trial Assessing the Effect of a Decisional Aid

DEDICACES2
Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Shared decision-making for organised breast cancer screening could be improved by fostering interaction and exchanges of information between women and GPs, for instance by including an assistance tool in the dispatch of the invitation letter for Organised Screening (OS) for breast cancer. In 2018 the national cancer Institute funded the development of a decisional aid (DA) on the theme of whether or not to take part in breast cancer screening, specific to the French setting. It is the website Discutons-mammo.fr DEDICACES project 1. DEDICACES 2 is a pragmatic, non-inferiority, population-based trial with a cluster design. The aim is to assess the impact of the dispatch of a leaflet informing women of the existence of the DA Discutons-mammo.fr on the uptake by eligible women of breast cancer screening in an organised setting in usual practical conditions and in the general population

NCT ID: NCT05607017 Recruiting - Breast Cancer Clinical Trials

Losartan in Prevention of Radiation-Induced Heart Failure

Start date: January 1, 2024
Phase: Early Phase 1
Study type: Interventional

This study is being done to see if losartan affects the chances of developing radiation-induced heart failure in patients who are receiving radiation therapy as part of standard of care treatment for breast cancer. The interventions involved in this study are: - Losartan - Radiation Therapy (standard of care)

NCT ID: NCT05605808 Recruiting - Breast Cancer Clinical Trials

Aerobic Training and Diet on the Immune System in Postmastectomy Patients Receiving Chemotherapy

Start date: May 20, 2022
Phase: N/A
Study type: Interventional

The purpose of the study was to investigate the impact of aerobic exercise combined with diet protocol on the immune system in post-mastectomy patients receiving chemotherapy.

NCT ID: NCT05602792 Recruiting - Breast Cancer Clinical Trials

A Study of T3011 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumors

Start date: April 21, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

A Phase I/IIa Study of the Safety and Tolerability of T3011 Administered via Intratumoral Injection in Patients with Advanced Solid Tumors

NCT ID: NCT05601440 Recruiting - Breast Cancer Clinical Trials

Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer

Start date: June 13, 2023
Phase: Phase 2
Study type: Interventional

This study is being done to answer the following question: Can testing breast cancer for DNA abnormalities or "biomarkers" help predict which patients are most likely to be helped by certain treatments? The pre-study screening is being done to test a sample of blood (or tumour tissue) for biomarkers to see if patients can participate in the study

NCT ID: NCT05600257 Completed - Breast Cancer Clinical Trials

The Effect of Digital Breast Tomosynthesis in Breast Cancer Long-term Survival: a Single Institution Study

Start date: September 1, 2011
Phase:
Study type: Observational

To investigate whether digital breast tomosynthesis (DBT) benefits survival improvement.

NCT ID: NCT05599334 Recruiting - Breast Cancer Clinical Trials

A Retrospective Observational Study of Patients With Early-stage HER2-positive Breast Cancer, Treated With Neratinib

NEAR
Start date: July 8, 2022
Phase:
Study type: Observational

The purpose of this study is to describe the demographic and clinical profiles of patients with early-stage HER2+ breast cancer treated with neratinib as an extended adjuvant therapy as part of the Early Access Program (EAP) in Europe.

NCT ID: NCT05598879 Recruiting - Breast Cancer Clinical Trials

Global Cardio Oncology Registry

G-COR
Start date: July 1, 2022
Phase:
Study type: Observational [Patient Registry]

G-COR is the first Global Prospective Cardio-Oncology Registry. It is a multinational, multicenter prospective observational cohort registry, with the goal of collecting clinical, laboratory, imaging, demographic, and socioeconomic data to identify risk factors associated with increased incidence of cancer therapy related cardiovascular toxicity (CTR-CVT) in different settings and to derive and validate risk scores for cardio oncology patients treated in different geographic locations throughout the world.

NCT ID: NCT05595330 Completed - Clinical trials for Breast Cancer Lymphedema

Effect of Lymphedema Prevention Program Based on Theory of Knowledge-attitude-practice on Postoperative Breast Cancer Patients

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

According to the inclusion and exclusion criteria, a total of 108 patients were enrolled and randomly divided into control group (n = 56) and intervention group (n = 52). The control group received routine nursing, while the intervention group received upper limb lymphedema prevention program for breast cancer patients after surgery. Before surgery, at the third chemotherapy (about 2.1 months after surgery) and the sixth chemotherapy (about 4.2 months after surgery), the self-designed general information questionnaire was used to investigate the patient's basic situation, and the corresponding tools were used to measure the volume of the patient's upper arm, the grip strength of the affected arm, and the range of motion of the affected shoulder joint.