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NCT04607070 Clinical Trial

Ischemic Strokes While on NOAC - How Compliance Matters

Atherosclerosis Clinical Trial

Official title:
Ischemic Strokes While on NOAC - How Compliance Matters

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04607070
Other study ID # Crec 2020.427
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date October 1, 2020
Est. completion date March 31, 2025

Study information
Verified date January 2024
Source Chinese University of Hong Kong
Contact Yiu Ming Bonaventure IP, MRCP
Phone 852-35053856
Email iym984@ha.org.hk
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study is aimed to depict the epidemiological trend, aetiologies, clinical characteristics, treatment options of IS-NOAC in face of the rapidly increasing NOAC usage. Knowledge on this ischaemic stroke entity will define clinical characteristics, identify preventable causes and inform resource allocation on the evaluation modalities, reperfusion strategies and forecast future burden of IS-NOAC.

Description:

Data will be retrieved from the stroke registry of Prince of Wales Hospital which recorded all in- and out-patients with stroke or transient ischaemic attack (TIA). All consecutive adult patients with known AF who developed ischaemic stroke or TIA in 2010, 2012, 2014, 2016 and 2018 (i.e. 5 full yearly time-points) and categorize the patients according to their anticoagulation status (elaborated below) with the inclusion and exclusion criteria stated will be recruited. All demographic data, blood results, imaging and assessment data will be retrieved from electronic patient record (CMS system) and stroke registry. All-cause mortality at 1 year will be verified via CMS system too.

Recruitment information / eligibility
Status Recruiting
Enrollment 870
Est. completion date March 31, 2025
Est. primary completion date September 30, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: 1. Patients who were ethnic Chinese 2. Patients with known AF 3. Patient who suffered from ischaemic stroke Exclusion Criteria: 1. Patient who are non-ethnic Chinese 2. Patient who suffered from haemorrhagic stroke

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Hong Kong Chinese University of Hong Kong Hong Kong

Sponsors (1)
Lead Sponsor Collaborator
Chinese University of Hong Kong

Country where clinical trial is conducted

Hong Kong, 

Outcome
Type Measure Description Time frame Safety issue
Primary Compliance affects the outcomes of ischemic stroke during NOAC usage. To depict epidemiological trend and aetiologies on different dosage of NOAC in stroke patients. 30 Sept 2021
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