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Vomiting clinical trials

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NCT ID: NCT04069806 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Preoperative Oral Carbohydrate for Nausea and Vomiting Prevention During Cesarian Section

POC-NaVoP
Start date: September 3, 2019
Phase: N/A
Study type: Interventional

Post-operative nausea and vomiting (PONV) in women undergoing subarachnoid anesthesia for Caesarean section is an important clinical problem. The aim of this study is to compare the effectiveness of oral carbohydrate loading to standard pre-operative fasting in patients undergoing elective cesarean section on the incidence and severity of PONV and biochemical parameters indicating ketosis.

NCT ID: NCT04060771 Recruiting - Anesthesia Clinical Trials

Post-Operative Nausea and Vomiting in Children Submitted to Strabismus Surgery

Start date: August 1, 2018
Phase: Phase 3
Study type: Interventional

Background: Postoperative nausea and vomiting (PONV) is one of the main causes of patient and family dissatisfaction, which may delay the onset of oral intake and postpone discharge. In pediatric patients, the incidence of PONV is high, and in some studies it can reach values of 70%. Strabismus surgery is considered an independent risk factor for PONV. Palonosetron is a second generation antiemetic drug, 5-hydroxytryptamine receptor antagonist, with a long half-life, which allows single dose administration and has been shown to be safe and effective in the treatment of chemotherapy induced nausea and vomiting, and has been used with satisfactory results in the prophylaxis of PONV in adult and pediatric patients. Studies involving palonosetron are still scarce.

NCT ID: NCT04047082 Recruiting - Clinical trials for Heart Valve Diseases

Online Videodensitometric Assessment of Aortic Regurgitation in the Cath-Lab

OVAL
Start date: May 15, 2019
Phase:
Study type: Observational [Patient Registry]

Following the high feasibility of analyses by core laboratory with videodensitometry determined in the ASSESS-REGURGE Registry, this is an early clinical feasibility study of online videodensitometric assessment of aortograms to quantitate aortic regurgitation (AR) in the cath lab, specifically in the setting of transcatheter aortic valve replacement (TAVR)

NCT ID: NCT04046068 Recruiting - Post-operative Pain Clinical Trials

Multimodal Perioperative Pain Management: ComfortSafe Program

Start date: May 11, 2020
Phase:
Study type: Observational

Proposed is a demonstration project to characterize the immediate, short-term and long-term pain and other post-operative outcomes of 60, self-selected breast (n=20), caesarian-section (n=20) and abdominal (n=20) surgical patients who receive opioid-sparing, multimodal anesthesia and pain management care as guided by the ComfortSafe Pyramid.

NCT ID: NCT04038879 Recruiting - Clinical trials for Mitral Regurgitation

Comparison Study of Echocardiography and Cardiovascular Magnetic Resonance Imaging in the Assessment of Mitral and Aortic Regurgitation

Start date: July 2010
Phase:
Study type: Observational

The primary treatment for patients determined to have severe aortic or mitral regurgitation is surgical repair or replacement their valves. The most commonly used tool to quantify the severity mitral and aortic regurgitation is echocardiography. Studies have shown that echocardiography may have significant limitations in quantifying regurgitant volume. MRI has recently been shown to easily and reproducibly quantify regurgitation. To better understand how to accurately quantify severity of regurgitation the investigators propose this study with the following aims: 1) compare MRI to echocardiography in the evaluation of regurgitant volume in patients with aortic or mitral regurgitation and 2) to assess which technique is better at predicting the response of the left ventricle to valve surgery.

NCT ID: NCT03851835 Recruiting - Diarrhea Clinical Trials

Multi-DOSE Oral Ondansetron for Pediatric Acute GastroEnteritis

DOSE-AGE
Start date: September 4, 2019
Phase: Phase 3
Study type: Interventional

A phase III, double-blind, parallel-design, randomized, placebo controlled trial to compare multi-dose oral Ondansetron with placebo as treatment for vomiting secondary to acute gastroenteritis (AGE), after Emergency Department discharge.

NCT ID: NCT03831633 Recruiting - Oncology Clinical Trials

Comparative Effectiveness of AKYNZEO® and Standard of Care (Including EMEND®) for the Prevention of Nausea and Vomiting (CINV) in Cancer Patients

Start date: September 19, 2018
Phase: Phase 4
Study type: Interventional

This pragmatic trial addresses the clinical gap through the generation of evidence on the comparative effectiveness between AKYNZEO® and Standard of Care (SoC, including EMEND®) in the real-life setting

NCT ID: NCT03795766 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Nausea and Vomiting After Gynecologic Surgery

Start date: January 1, 2019
Phase:
Study type: Observational

In this cross-section study, all patients in the gynecologic ward of Peking Union Medical College Hospital will accepted a survey about the prevalence and severity of nausea and vomiting according to visual analogue scale and WHO classification. Epidemiological, surgical, anaesthetic characteristics and post-operative treatment are considered as predictors for the post-operative nausea and vomiting. The primary objective is the incidence of nausea and vomiting. The secondary objective is the possible predictors of nausea and vomiting.

NCT ID: NCT03783182 Recruiting - Pain Clinical Trials

Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy

Start date: September 10, 2019
Phase: Phase 4
Study type: Interventional

Betamethasone is currently given routinely in conjunction with tonsillectomy surgery at the majority of Ear, Nose & Throat clinics in Sweden. The scientific evidence regarding the effects of betamethasone in adults is limited when it comes to postoperative nausea (PONV), pain and postoperative bleeding.

NCT ID: NCT03740672 Recruiting - Gynecologic Cancer Clinical Trials

Adherence to the Antiemesis National Comprehensive Cancer Network (NCCN) Guideline

Start date: November 22, 2018
Phase:
Study type: Observational

This study aims to investigate the adherence to the antiemesis NCCN guideline in Chinese patients of gynecologic malignancies, who are given chemotherapy treatment. The risk of chemotherapy induced nausea and vomiting (CINV) is calculated by the questionnaire supported by the website "CINV Risk Assessment" (http://www.riskcinv.org/).