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Vomiting clinical trials

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NCT ID: NCT04430361 Recruiting - Tumor Clinical Trials

the Efficacy and Safety of 5-HT3 Receptor Antagonist, Dexamethasone or Megestrol Acetate Dispersible Tablets in the Control of Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy

Start date: September 7, 2018
Phase: Phase 2
Study type: Interventional

To compare the efficacy and safety of megestrol acetate dispersible tablets combined with 5-HT3 receptor antagonist and dexamethasone triple antiemetic regimen and 5-HT3 receptor antagonist and dexamethasone combined antiemetic regimen in the control of CINV induced by hyperemetic chemotherapy.

NCT ID: NCT04297293 Recruiting - Day Surgery Clinical Trials

Ramosetron OD Tablet and Postdischarge Nausea and Vomiting

Start date: May 12, 2020
Phase: Phase 4
Study type: Interventional

Postoperative nausea and vomiting after general anesthesia is one of the common anesthetic complications. If the patient is discharged from the hospital after surgery, proper treatment may be delayed or impossible if nausea and vomiting occurred. Thus, it is necessary to prevent these symptoms beforehand. Patients who underwent day-surgery will be treated with prophylactic ramosetron orally disintegrating tablets to determine whether the frequency of nausea and vomiting is decreased when the patient returned home after discharge.

NCT ID: NCT04250844 Recruiting - Vomiting Clinical Trials

Use of Intrapyloric Botulinum Injections in Children

Start date: March 10, 2020
Phase:
Study type: Observational

This study aims to evaluate the effect of intrapyloric botulinum toxin in children with feeding disorders.

NCT ID: NCT04191694 Recruiting - PONV Clinical Trials

Chewing Gum to Prevent Nausea and Vomiting After Caesarean Section Under Spinal Anaesthesia

Start date: October 28, 2019
Phase: N/A
Study type: Interventional

Our study aims to determine if there is a difference in a self-reported incidence of nausea and vomiting in women who are given chewing gum following elective caesarean section under spinal anaesthesia compared to those who do not receive chewing gum

NCT ID: NCT04182828 Recruiting - Post-operative Pain Clinical Trials

Effect of Intravenous Lidocaine on Immediate Post-operative Pain, Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Placebo Controlled Trial

Start date: November 25, 2019
Phase: Phase 4
Study type: Interventional

Lidocaine is a drug that has multiple uses. One of these is that when intravenously administered it is effective in reducing post-operative pain. The aim of this study is to investigate the beneficial effects of intravenous lignocaine on reducing pain, nausea and vomiting after laparoscopic cholecystectomy. Also, by this research, we are aiming to find a suitable alternative analgesic.

NCT ID: NCT04181346 Recruiting - Nausea Clinical Trials

Pregabalin for the Prevention of Chemotherapy Induced Nausea and Vomiting

Start date: September 1, 2019
Phase: Phase 2
Study type: Interventional

phase II randomized, double-blind, placebo-controlled trial to investigate whether pregabalin can improve the complete control of nausea and vomiting (primary end point)

NCT ID: NCT04150614 Recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron

Start date: May 14, 2020
Phase: Phase 4
Study type: Interventional

Patients undergoing either an autologous or allogeneic hematopoietic stem cell transplant (HSCT) and receiving preparative chemotherapy experience a considerable amount of chemotherapy-induced nausea and vomiting (CINV). Current strategies at reducing CINV in this patient population are suboptimal due to lack of efficacy and supportive evidence, potential for increased adverse events, and drug-drug and drug-disease contraindications.

NCT ID: NCT04141514 Recruiting - Vomiting Clinical Trials

Effects of Short-term Therapeutic Fasting on Nausea and Vomiting Due to Chemotherapy

CHEMO-FAST
Start date: January 20, 2022
Phase: N/A
Study type: Interventional

This study aims to estimate the effect of the practice of a short-term partial fasting compared to a usual alimentation on nausea and vomiting within 5 days after the start of a chemotherapy session on 2 successive chemotherapy courses (4 sessions of chemotherapy) in patients starting treatment with highly emetogenic chemotherapy (ABVD or AVD protocol).

NCT ID: NCT04116697 Recruiting - Anxiety Clinical Trials

A Randomized Controlled Trial to Evaluate the Efficacy of Acupuncture Versus Aromatherapy as Treatments to Lessen Nausea, Vomiting and Anxiety Associated With Adriamycin and Cytoxan

Start date: October 23, 2019
Phase: N/A
Study type: Interventional

The overall goal of this study is to explore the effectiveness of using acupuncture versus aromatherapy, in conjunction with standard of care anti-emetics, to decrease chemotherapy induced nausea, vomiting, and anxiety in breast cancer patients undergoing Adriamycin and Cytoxan. This study also aims to determine if aromatherapy and anti-emetics is more effective than acupuncture and anti-emetics in treating nausea, vomiting, and anxiety in patients receiving Adriamycin and Cytoxan and if acupuncture and anti-emetics is more effective than aromatherapy and anti-emetics in treating nausea, vomiting, and anxiety in patients receiving Adriamycin and Cytoxan.

NCT ID: NCT04110080 Recruiting - Pain, Postoperative Clinical Trials

Enhanced Recovery After Surgery in Kidney Transplant Donors

Start date: September 12, 2019
Phase: N/A
Study type: Interventional

Enhanced recovery after surgery (ERAS) pathways are designed to optimize perioperative management, improving patient outcomes and satisfaction through multimodal techniques. Living kidney transplant donors are typically healthy individuals who undergo laparoscopic nephrectomy. The most significant hindrance to discharge to return to activities of daily living is frequently return of bowel function and postoperative pain. Through a randomized controlled trial design, we will evaluate the effectiveness of implementing an ERAS pathway. We hypothesize that preoperative patient optimization through exercise, carbohydrate loading, and counseling on expectations, in addition to multimodal pain management strategies which limit opioids would allow faster recovery, early bowel function, decreased postoperative pain, increased patient satisfaction and shorter length of stay. The study population will include a total of 42 patients (age 18-80) who are American Society of Anesthesiologists (ASA) Physical Status (PS) 1-3, undergoing living donor nephrectomy. Our primary outcome measures will be postoperative opioid consumption. Secondary outcome measures are: postoperative pain score, time to return of bowel function, ambulation, first oral intake postoperatively, and patient satisfaction scores. Other objectives include reducing readmissions, shorter hospital length of stay and decreased operative complications, including nausea, vomiting and wound infection.