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Diarrhea clinical trials

View clinical trials related to Diarrhea.

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NCT ID: NCT06363890 Not yet recruiting - Travelers Diarrhea Clinical Trials

Etiology of Travelers' Diarrhea in Australian Tourists Traveling to Southeast Asia

AusTD
Start date: May 1, 2024
Phase:
Study type: Observational

The study proposed here will determine the frequency and etiology of diarrhea in Australian adult tourists traveling to Southeast Asia, including Cambodia, Indonesia, Laos, Malaysia, Myanmar, the Philippines, Thailand, Timor-Leste, and Vietnam. The results from this study will inform the feasibility and design of subsequent clinical trials of travelers' diarrhea interventions in this population.

NCT ID: NCT06362096 Not yet recruiting - Breast Cancer Clinical Trials

A Multicenter, Prospective Study of Diarrhea Tolerance of Pyrotinib Combined With Trastumab and Taxane in the First-line Treatment of HER2-positive Advanced Breast Cancer

Start date: May 2024
Phase: Phase 2
Study type: Interventional

To explore a reasonable and effective way to reduce the incidence of grade 3 or above diarrhea caused by pyrotinib

NCT ID: NCT06356545 Not yet recruiting - Diarrhea Infantile Clinical Trials

Phenotype and Multi-omics Analysis of Children With Congenital Diarrhea and Enteropathy in China

Start date: April 2024
Phase:
Study type: Observational

This study will establish a clinical cohort of children with congenital diarrhea and enteropathy (CODE), mine biomarkers of CODE through multi-omics technology and construct a clinical risk prediction model.

NCT ID: NCT06346847 Not yet recruiting - Clinical trials for Diarrhea-Predominant Irritable Bowel Syndrome

Study to Assess Effects of Pasteurized Akkermansia Muciniphila vs Placebo in Participants With Diarrhea-predominant IBS

PAM-DIGEST
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The present study is a randomized, double-blind, placebo-controlled, parallel group clinical study that assesses the effect of pasteurized Akkermansia muciniphila on the complaints of subjects with moderate to severe diarrhoea-predominant irritable bowel syndrome (IBS-D). The trial is also evaluating the potential of pAkk on anxiety, low mood and stress of the participants, as well as its safety and tolerability. The intervention duration for all the study participants is 12 weeks (intervention phase). Subsequently, the participants will be invited to return to site for an end of study assessment after 21 days of no intervention (post-intervention phase).

NCT ID: NCT06337695 Not yet recruiting - Cancer Clinical Trials

VERIFY: Vedolizumab for the Prevention of Immune Checkpoint Inhibitor Related Diarrhea or Colitis in Patients With Cancer

Start date: July 1, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to assess the prevention of immune checkpoint inhibitors (ICIs) related diarrhea/colitis using vedolizumab in participants with unresectable stage III or metastatic stage IV cancer, starting standard of care (SOC) immunotherapy

NCT ID: NCT06333795 Not yet recruiting - Diarrhea Clinical Trials

Faecal Microbiota Transplantation Against Chronic Diarrhea in Patients With Systemic Sclerosis

FaeMiCue
Start date: April 1, 2024
Phase: N/A
Study type: Interventional

This clinical trial aims to assess the safety and effectiveness of faecal Microbiota Transplantation (FMT) in improving chronic diarrhea symptoms among patients with systemic sclerosis.

NCT ID: NCT06318078 Recruiting - Malaria Clinical Trials

Buikwe Electronic Community Health Information System Impact Study

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate the impact of the eCHIS intervention on key child health outcomes.

NCT ID: NCT06297421 Not yet recruiting - Clinical trials for Irritable Bowel Syndrome With Diarrhea

A Study to Evaluate the Efficacy and Safety of Homogenized Prescription Enterobacteria Capsule in Patients With IBS-D

Start date: May 2024
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Homogenized Prescription Enterobacteria Capsule compared with placebo in the treatment of participants with irritable bowel syndrome with diarrhea.

NCT ID: NCT06290089 Recruiting - ETEC Diarrhea Clinical Trials

Pre-Study of Wild Type Enterotoxigenic E. Coli (ETEC) Strain for Verification of a Planned Challenge Dose

Start date: February 12, 2024
Phase: N/A
Study type: Interventional

This is an open label study with the aim to estimate the incidence of moderate and severe diarrhea among participants challenged with an enterotoxigenic E. coli (ETEC) strain. This strain is planned to be used in a subsequent challenge study on the efficacy of an oral inactivated ETEC vaccine. The study will be conducted at one site; the Center for Immunization Research, Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland, United States.

NCT ID: NCT06285851 Completed - Constipation Clinical Trials

A Novel Iron Supplement for Athletes: Phase I

Start date: November 23, 2023
Phase: N/A
Study type: Interventional

Female endurance athletes are susceptible to iron deficiency and this can impact their exercise performance. This study is a pilot trial to assess the tolerability of a novel iron supplement prior to conducting a clinical trial on the efficacy of the developed novel iron supplement on iron status and performance.