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Surgery clinical trials

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NCT ID: NCT04817813 Not yet recruiting - Breast Cancer Clinical Trials

Long-term Outcomes After Breast Cancer Liver Metastasis Surgery: an European, Retrospective, Snapshot Study

LIBREAST
Start date: March 15, 2021
Phase:
Study type: Observational

Breast cancer ranks as the top leading malignant tumors among females, and also accounts for the most common cause of tumor related mortality in females worldwide. Approximately, 20-30% of breast cancer cases develop metastasis, while 50% of patients will suffer from breast cancer liver metastasis. The proper indication for surgical treatment of breast cancer liver metastasis is still a matter of discussion. Surgery is becoming more practical and effective than conservative treatment in improving the outcomes of patients with breast cancer liver metastasis and liver metastasis surgery is included in an onco- surgical strategy.

NCT ID: NCT04791410 Not yet recruiting - Hypertension Clinical Trials

Clinical Study on the Efficacy of Microvascular Decompression in the Treatment of Neurogenic Hypertension

Start date: March 2021
Phase:
Study type: Observational [Patient Registry]

Hypertension has always been a threat to human health, so the prevention and treatment is of great significance. At present, the treatment of primary hypertension is mainly drug treatment, but many patients can not control their blood pressure in the normal range. Therefore, it is urgent to explore new and effective treatment methods. Microvascular compression type of neurogenic hypertension is mainly due to abnormal tortuous vascular pulsatile compression of blood pressure center - rostral ventrolateral medulla (RVLM), resulting in the release of sympathetic active substances, leading to hypertension. The purpose of this study is to explore the efficacy and safety of microvascular decompression for hypertension in patients of hemifacial spasm complicated with hypertension, and to explore the common characteristics of patients with effective decompression. The type of study design was prospective cohort study. According to certain inclusion and exclusion criteria, patients with RVLM compression were treated with RVLM decompression at the same time of facial nerve decompression. Patients who were followed up for 3 months were taken as control group, and the blood pressure of the two groups were measured after 3 months. The main outcome measure was 24-hour ambulatory systolic blood pressure change from baseline to 3 months.

NCT ID: NCT04774965 Not yet recruiting - Surgery Clinical Trials

The Effects of SlumberCurve™ Following Rotator Cuff Surgery: A Randomized Control Trial

Start date: June 30, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effects of a novel sleep aid known as SlumberCurve™, which serves as an adjustable form of a wedge pillow, on sleep quality and pain management following rotator cuff repair. The researchers hypothesize that SlumberCurve™ will significantly improve sleep quality and reduce night-time pain.

NCT ID: NCT04749472 Not yet recruiting - Surgery Clinical Trials

Biomechanical Analysis of Scapula and Humerus With Different Shoulder Slings

Start date: February 15, 2021
Phase: N/A
Study type: Interventional

Participants will be measured with motion monitor system while using 6 different slings. Measurement order will be randomized, and 5 minutes resting period will be given prior measurement. Scapula, humerus and thorax positions will be recorded in resting position and then with slings.

NCT ID: NCT04719767 Not yet recruiting - Surgery Clinical Trials

Application of Visual Laryngeal Mask Airway Combined With Endotracheal Intubation in General Anesthesia

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

To study the advantages of visual laryngeal mask combined with endotracheal intubation in general anesthesia surgery, we compared intubation time, intubation times and intubation success rate of endotracheal intubation through laryngeal mask airway under visual and non-visual conditions, at the same time, the laryngeal mask displacement rate, volume of secretion in airway, the incidence of laryngeal spasm, the incidence and severity of postoperative oropharyngeal pain were also compared between two groups.

NCT ID: NCT04677673 Not yet recruiting - Gastric Cancer Clinical Trials

Neoadjuvant Chemotherapy Plus Surgery Versus Surgery First For Elderly Gastric Cancer Patients

RJGC-Senile
Start date: January 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The main purpose of this study is to compare the feasibility and efficacy of neoadjuvant chemotherapy (modified SOX) for elderly patients with locally advanced gastric cancer.

NCT ID: NCT04670887 Not yet recruiting - Surgery Clinical Trials

Comparison of Surgery and Active Surveillance in the Treatment of Bosniak III Renal Cysts

Start date: March 15, 2021
Phase: N/A
Study type: Interventional

The incidence of renal cysts is rising due to increased abdominal imaging. Renal complicated cysts have been traditionally classified according to the Bosniak classification, which distinguishes cystic masses by specific features of walls and septa. The categories I and II are benign and class IIF most probably benign but needs a short radiological follow-up. Categories III and IV have been traditionally operated due to the increased risk of renal cell carcinoma. However, recently published studies show that approximately 50% of the operated Bosniak III cystic masses are benign, which means that half of the cases are overtreated by surgery. It has also been shown that surgical pathology of stable Bosniak IIF cysts is malignant in less than 1%, while the cysts, which are upgraded to higher Bosniak classes will show malignant surgical pathology in 85%. So far, there is lack of prospective data on active surveillance in Bosniak III cystic masses. The aim of the study is to compare active surveillance and surgery in patients with Bosniak III renal cystic masses. Patients will be randomized in active surveillance or immediate surgical excision of a cystic mass. In the active surveillance group, patients are followed according to the study protocol for 10 years and treated with delayed surgery if the cystic mass upgrades into Bosniak IV/solid, becomes symptomatic or grows over a preclassified threshold. The primary objective is to compare surgical pathology between patients treated with immediate surgery versus delayed surgery. According to recent retrospective data, active surveillance of Bosniak III cystic masses is reasonable and oncologically safe. Therefore a prospective randomized controlled trial is needed to get high level evidence to support a change in the treatment strategy. The study may significantly reduce unnecessary operations performed in patients with Bosniak III cystic masses.

NCT ID: NCT04616092 Not yet recruiting - Surgery Clinical Trials

Effect of Preoperative Intravenous Ferric Carboxymaltose for Clipping Surgery

PICASA
Start date: November 2020
Phase: Phase 4
Study type: Interventional

Hypothesis: Correction of preoperative anemia can reduce the need for intra-/postoperative RBC transfusions and can improve surgical outcomes.

NCT ID: NCT04514718 Not yet recruiting - Quality of Life Clinical Trials

Low Energy HoLEP on IPSS

Start date: August 24, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to prove that low-energy (30W) Holmium laser prostatectomy (Holeb) is not inferior to high-energy (100W) Holmium laser prostatectomy (safety and effectiveness)

NCT ID: NCT04509986 Not yet recruiting - Covid19 Clinical Trials

GlobalSurg-CovidSurg Week

Start date: October 1, 2020
Phase:
Study type: Observational

Observational study to determine the optimal timing for surgery following SARS-CoV-2 infection and assess key global surgery indicators.