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Surgery clinical trials

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NCT ID: NCT05286580 Terminated - Surgery Clinical Trials

Standardization of Non-academic Center Surgical Morbidity and Mortality Conference: a Type I Hybrid Implementation Non-clinical Trial.

Start date: March 24, 2022
Phase: N/A
Study type: Interventional

- Specific Aim 1: Determine impact of standardized morbidity and mortality (M&M) toolkit on provider satisfaction with, and perceived impact of, M&M conference. - Specific Aim 2: Identify barriers and facilitators to toolkit implementation.

NCT ID: NCT04990804 Terminated - Surgery Clinical Trials

Opioid Free vs. Standard Perioperative Pain Regimen for Anterior Cervical Discectomy and Fusion (ACDF) Surgery

Start date: August 1, 2021
Phase: Phase 4
Study type: Interventional

Patients undergoing 1-3 level Anterior Cervical Discectomy and Fusion (ACDF) at the levels between C2 and T1 will be enrolled into this randomized prospective study. All patients enrolled in this study will undergo a trial of non-surgical treatment prior to the recommendation for surgery. After enrollment, patients will be randomized utilizing a block randomization strategy to one of two treatment groups - a standard opioid-containing postoperative pain regimen versus a non-opioid postoperative pain regimen. Postoperative outcomes will be assessed.

NCT ID: NCT04879823 Terminated - Surgery Clinical Trials

Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity

Start date: August 5, 2021
Phase: Phase 3
Study type: Interventional

The goal of this study is determine if an oral systemic course of steroids is a safe and effective option in lowering pain and complications following adenotonsillectomy in various pediatric age groups. A double blind, placebo-controlled randomized clinical trial of steroids (dexamethasone) versus placebo postoperatively will be performed. Investigators will determine if there is a difference in post-operative pain and complications between groups.

NCT ID: NCT04812704 Terminated - Cancer Clinical Trials

Protein Supplements in Association With Prehabilitation Program for Cancer Patients Before Surgery

Start date: March 9, 2021
Phase: N/A
Study type: Interventional

The aim of study is to analyse the feasibility of the use of nutritionnal complements after exercices before surgery for cancer. Body composition, muscle function and muscle mass will be analyse too.

NCT ID: NCT04663269 Terminated - Surgery Clinical Trials

Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy

Start date: February 24, 2020
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if adding a spinal block (medicine that will numb parts of the body to block pain) along with standard pain control at the incision site will decrease the need for narcotics for pain management and decrease the percentage of patients requiring hospital admission for pain control during postoperative , in-hospital, care after a percutaneous nephrolithotomy (PCNL) (surgery to remove kidney stones), commonly called PERC.

NCT ID: NCT04610606 Terminated - Lung Cancer Clinical Trials

Pilot Prehabilitation Intervention in Lung Cancer

Start date: October 11, 2019
Phase: N/A
Study type: Interventional

Lung cancer is the second most prevalent cancer in Canada and the leading cause of cancer-related mortality worldwide. Patients diagnosed at earlier (non-metastatic) stages are potential candidates for surgical tumor removal. However, they often present with poor nutritional status and physical function adding to the major catabolic stress imposed by surgery that negatively impacts recovery and survival after surgery. The purpose of this study is to investigate the potential benefits of a prehabilitation program that includes a combined nutritional supplement (whey protein, leucine, vitamin D and omega-3 fatty acids) with exercise and relaxation techniques for 4 weeks before surgery and continued for 8 weeks after surgery on functional pre- and postoperative outcomes, versus standard hospital care (control). Investigators will study whether the prehabilitation program improves physical performance, muscle mass and quality of life in patients undergoing lung cancer resection. The specific objective of this pilot study is to test feasibility and adherence to intervention, and generate pilot data to inform the design of a larger trial.

NCT ID: NCT04559178 Terminated - Surgery Clinical Trials

Fluid Challenges and Microcirculation

FC
Start date: January 25, 2021
Phase:
Study type: Observational

The goal of this prospective observational study is to assess the impact of fluid challenge administration on macro and microcirculation in patients situated in the gray zone during a high risk abdominal surgery

NCT ID: NCT04506372 Terminated - Surgery Clinical Trials

Management of Angiotensin Inhibitors During the Perioperative Period

AIPOP
Start date: September 11, 2020
Phase: N/A
Study type: Interventional

This is a multicenter randomized clinical trial to determine the effect of continuation versus withdrawal of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) in the perioperative period on postoperative complications.

NCT ID: NCT04469881 Terminated - Surgery Clinical Trials

Netflix Streaming Services in the Operating Room During Total Knee Replacement - a Feasibility Study

Start date: November 24, 2020
Phase: N/A
Study type: Interventional

The purpose of this research study is to test the safety, tolerability, and effectiveness of watching streamed videos through virtual reality (VR) goggles during surgery. The results of this study will be used to evaluate whether video-streaming services on VR goggles are worthwhile additions to standard anesthesia care during total knee surgery.

NCT ID: NCT04469205 Terminated - Breast Cancer Clinical Trials

Study to Assess the Impact of Personalized Coaching on the Time Period and Quality of Return to Work After Breast Cancer

OPTICOACH
Start date: October 5, 2020
Phase: N/A
Study type: Interventional

Evaluate the impact of coaching sessions on the return to work rate (number of patients returning at work / total number of patients per arm) 6 months after inclusion in the study for breast cancer in professionnally active patients.