Neurofeedback-enhanced Mindfulness Meditation for the Treatment of Affective and Attentional Disturbances in Patients With Traumatic Brain Injury
Spaulding Rehabilitation Hospital is conducting a research study evaluating the effectiveness of the brain-training product, MUSE, an EEG-guided neurofeedback device designed to assist in cultivating a relaxed, attentive state of mind during meditation. The investigators study aims to evaluate whether such a tool could be useful in treating persistent traumatic brain injury symptoms such as inattention, impulsivity, irritability, or dysregulated mood.
NCT02615535 — Traumatic Brain Injury
Status: Completed
http://inclinicaltrials.com/traumatic-brain-injury/NCT02615535/
Couple-Based Meditation for Metastatic Lung Cancer Patients and Their Partners
Objectives: Our specific aims are to: Aim 1: Examine the feasibility of a couple-based meditation program in 50 patients with metastatic lung cancer and their partners. Aim 2: Establish the initial efficacy of a couple-based meditation program in patients and their partners regarding physical, psychological, and spiritual quality of life outcomes.
NCT02596490 — Lung Cancer
Status: Recruiting
http://inclinicaltrials.com/lung-cancer/NCT02596490/
The Effects of Mindfulness Meditation on Fibromyalgia-Related Pain
The purpose of this study is to examine the effects of a brief mindfulness meditation intervention on clinical and experimental pain in fibromyalgia (FM) patients as compared to a wait-list control condition. Based on prior research, investigators' working hypothesis is that this intervention will decrease the severity of FM-associated clinical pain and experimentally induced pain in comparison to pre-intervention scores and a wait-list control group. Additionally, based on prior work, investigators postulate that mindfulness meditation training will decrease a) depression, b) state anxiety, c) overall disease severity, and d) perceived stress, while increasing e) quality of sleep, and f) mindfulness skills in comparison to pre-intervention scores and the wait-list control group. Investigators will also be testing if decreases in pain ratings during meditation correspond to increases in parasympathetic activity. The relative systemic contributions of the parasympathetic and sympathetic branches of the Autonomic Nervous System (ANS) can be examined by measuring heart rate variability (HRV), or the variability in the beat-to-beat interval. Fast acting, parasympathetically-mediated high frequency (HF) changes in heart rate variability (HF HRV; 0.15-0.40 Hz) provide a reliable indicator of parasympathetic activity. Importantly, decreased HF HRV correlates with increased pain. Investigators therefore will employ psychophysical and physiological methodologies to test the hypothesis that the analgesic effects of mindfulness meditation in FM patients are associated with increases in HF HRV.
NCT02581332 — Fibromyalgia
Status: Withdrawn
http://inclinicaltrials.com/fibromyalgia/NCT02581332/
Mechanisms of Mindfulness Meditation, Cognitive Therapy, and Mindfulness-Based Cognitive Therapy for Low Back Pain
Up to 80% of Australians experience back pain and 10% have significant disability as a result. There is a critical need for the development and evaluation of innovative treatments that have the capacity to target the multidimensional nature of chronic low back pain. This study will compare the effects and mechanisms of Mindfulness Meditation, Cognitive Therapy, and Mindfulness-Based Cognitive Therapy for chronic low back pain. Results will ultimately lead to streamlined interventions designed to efficiently maximise benefit.
NCT02478307 — Low Back Pain
Status: Completed
http://inclinicaltrials.com/low-back-pain/NCT02478307/
Meditation or Health & Wellness Education Via Internet for Adults 50-80 Years Old
1. Telephone Eligibility Screening 2. Baseline Visit, includes online questionnaires, physical measures, cognitive tasks, voice recordings, physical recordings of brain waves, heart rate, breathing rate, and sweat during computer tasks. Collect saliva samples, questionnaire data, and respond to handheld device that rings randomly for the seven days following the visit. 3. Randomized to receive (a) an internet-based Mindfulness Meditation program, (b) an internet-based Health & Wellness Education program, or (c) no training. IF assigned to receive a training program, participants complete weekly one-hour online trainings and daily home practice for 6 weeks 4. Endpoint Visit (same as Baseline), scheduled 8 weeks after Baseline 5. All participants receive Meditation and Education programs after the Endpoint Visit 6. Online questionnaire follow-up 6 months after the Endpoint
NCT02467660 — Stress, Psychological
Status: Completed
http://inclinicaltrials.com/stress-psychological/NCT02467660/
The Effect of Inquiry Based Stress Reduction (IBSR) Meditation Technique on Levels of Burnout and Wellbeing Among Teachers.
The purpose of this study is to investigate the effect of Inquiry based stress reduction (IBSR) meditation technique on levels of burnout and wellbeing among teachers.
NCT02455947 — Burnout, Professional
Status: Completed
http://inclinicaltrials.com/burnout-professional/NCT02455947/
Use of a Functional Neuroimaging Battery for the Evaluation of a Meditation
Over 2 decades scientists have been studying the effect on brain function from meditation practices. The purpose of this study is to measure the effect of a meditation retreat program on serotonin and dopamine transporter binding and changes in cerebral blood flow. The retreat program that will be followed is a week-long retreat called the Ignatian Retreat.
NCT02443766 — Healthy
Status: Completed
http://inclinicaltrials.com/healthy/NCT02443766/
Being Present: Audio-Based Mindfulness Meditation Intervention for Colorectal Cancer Patients and Caregivers
This is a audio based mindfulness meditation intervention for colorectal cancer patients and caregivers. A 8-week single arm study will be conducted among University of California, San Francisco (UCSF) patients with metastatic colorectal cancer undergoing chemotherapy and caregivers of these patients (44 participants total).
NCT02423720 — Colorectal Cancer
Status: Completed
http://inclinicaltrials.com/colorectal-cancer/NCT02423720/
An Examination of Potential Neurochemical and Cognitive Mediators of the Relationship Between Mindfulness and Emotion Regulation in Individuals With Multiple Sclerosis: An Internet Based Self-Guided Pilot Study.
The aim of this study is to examine whether meditation delivered by the internet improves mood and attention as well as increases levels of dopamine in individuals who have been diagnosed with Multiple Sclerosis.
NCT02391298 — Multiple Sclerosis
Status: Completed
http://inclinicaltrials.com/multiple-sclerosis/NCT02391298/
A Proof of Concept and Feasibility Trial of Compassion Meditation for PTSD
The goal of this project is to refine an existing compassion meditation protocol for individuals with posttraumatic stress disorder (PTSD), to examine the safety and feasibility of this approach and to collect data to make initial estimates of efficacy.
NCT02372396 — Posttraumatic Stress Disorder
Status: Completed
http://inclinicaltrials.com/posttraumatic-stress-disorder/NCT02372396/