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Lung Cancer clinical trials

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NCT ID: NCT04846985 Not yet recruiting - Lung Cancer Clinical Trials

Nutritional Problems in Pallative Cancer

Start date: April 26, 2021
Phase:
Study type: Observational

The aim of this study is to investigate those nutritional problems contributing to loss of lean body mass in lung and pancreas cancer patients in chemotherapy. Furthermore to investigate alterations in taste and how they correlates with changes in following factors: nutritional intake, physical activity, appetite, food preferences, side effects, fatique and meal perception.

NCT ID: NCT04844736 Not yet recruiting - Lung Cancer Clinical Trials

Testing the Feasibility of a Simplified Workflow for Lung Cancer

Start date: July 2021
Phase: N/A
Study type: Interventional

The purpose of this research study is to see if adding an "extra" check by formal radiology review is possible without disrupting the normal processes that take place to develop and prepare a safe radiation treatment plan for patients.

NCT ID: NCT04842812 Recruiting - Breast Cancer Clinical Trials

Engineered TILs/CAR-TILs to Treat Advanced Solid Tumors

Start date: January 1, 2021
Phase: Phase 1
Study type: Interventional

Tumor infiltration lymphocytes (TILs) have been harvested from advanced cancer patients and constructed to knockout PD1 gene and express scFvs against both PD1 and CTALA4 and CARs against various antigens, followed by transfusion into the patients. The safety, tolerance, and preliminary clinical efficacy of the TILs will be evaluated.

NCT ID: NCT04841811 Not yet recruiting - Lung Cancer Clinical Trials

ctDNA Guiding Treatment After Almonertinib Induction Therapy for EGFRm+ NSCLC in the MDT Diagnostic Model

APPROACH
Start date: August 15, 2021
Phase: Phase 2
Study type: Interventional

This is a multi-center, open phase II clinical study, in patients with unresectable stage III non-small cell lung cancer,to evaluate the effectiveness and safety of Almonertinib induction therapy, and ,to evaluate the effectiveness and safety of different treatment decisions guided by ctDNA dynamic monitoring after local treatments (surgical or radical radiotherapy) evaluated by MDT. The study includes a screening period (not more than 28 days after the subject signs informed consent to before the first medication), treatment period (including induction\MDT+topical therapy\adjuvant or consolidation therapy) and follow-up period (including safety and survival) .

NCT ID: NCT04837677 Not yet recruiting - Breast Cancer Clinical Trials

A Study of PRT1419 in Patients With Advanced Solid Tumors

Start date: April 15, 2021
Phase: Phase 1
Study type: Interventional

This is a Phase 1 dose-escalation study of PRT1419, a myeloid cell leukemia 1 (MCL1) inhibitor, in patients with advanced solid tumors. The purpose of this study is to define the dosing schedule, maximally tolerated dose and/or estimate the optimal biological dose to be used in subsequent development of PRT1419.

NCT ID: NCT04836975 Not yet recruiting - Lung Cancer Clinical Trials

Reveal the Patterns of Presentation, Management and Outcome of Patients With SCLC and Stage III NSCLC in Saudi Arabia:

REVEAL
Start date: April 30, 2021
Phase:
Study type: Observational

A retrospective, multi-centre, observational study to describe the treatment patterns, the demographic, clinical outcomes, treatment effectiveness, and healthcare resource utilization (HCRU) for patients diagnosed with primary Small Cell Lung Cancer SCLC (Extensive stage & Limited Stage)and stage III NSCLC in a real-world setting

NCT ID: NCT04833205 Recruiting - Lung Cancer Clinical Trials

Clinical Efficacy and Safety of EGFR-TKI Combined With Nimotuzumab in the Treatment of Leptomeningeal Metastases From Lung Cancer

Start date: April 19, 2021
Phase: Phase 2
Study type: Interventional

Clinical Efficacy and Safety of EGFR-TKI Combined With Nimotuzumab in the Treatment of Leptomeningeal Metastases From Lung Cancer.

NCT ID: NCT04829422 Available - Lung Cancer Clinical Trials

Early Access Program of Lazertinib in Republic of Korea

Start date: n/a
Phase:
Study type: Expanded Access

This early access program will be conducted to provide access to Lazertinib for adult patients with locally advanced or metastatic Non-small Cell Lung Cancer (NSCLC) with T790M mutation-positive after 1st/2nd generation EGFR TKIs Therapy.

NCT ID: NCT04827667 Recruiting - Lung Cancer Clinical Trials

Impact of PD1-lymphocytes in Bronchoalveolar Lavage of Patients With Lung Cancer

Start date: March 18, 2021
Phase:
Study type: Observational

The aim of this trial is to assess PD1-lymphocytes in bronchoalveolar lavage in patients with lung cancer, ILD and asthma.

NCT ID: NCT04826835 Not yet recruiting - Lung Cancer Clinical Trials

A Prehabilitation Program to Boost Postoperative Functional Capacity in Surgical Lung Cancer Patients

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

This research study is evaluating a prehabiliation intervention designed to improve postoperative functional capacity (measured by 6-minure walking distance) in individuals undergoing lung resection for cancer.