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Pain clinical trials

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NCT ID: NCT04404959 Recruiting - Pain Clinical Trials

Perioperative Pain and Delirium in Geriatric Patients With Hip Fracture

Delirium-Hip
Start date: May 10, 2019
Phase: N/A
Study type: Interventional

The objective of this trial will be to establish whether the ultrasound-guided suprainguinal fascia iliaca compartment block is capable of protecting geriatric patients with hip fracture from delirium as compared to placebo

NCT ID: NCT04399850 Recruiting - Pain Clinical Trials

Impact of Hypnosis During Invasive Procedure in Intensive Care Unit

HYPNOICU
Start date: September 28, 2020
Phase: N/A
Study type: Interventional

Pain during ICU stay remains one of the major complaints for patients. Beside pain intensity, well described by patients' self reports, pain distress, which is an emotional experience, cannot be treated with usual analgesia. The aim of the study is to analyze the impact of hypnosis on pain intensity and distress on short and long term outcomes in non-sedated ICU patients.

NCT ID: NCT04385082 Recruiting - Pain Clinical Trials

Cannabis Effects as a Function of Sex (CanSex)

CanSex
Start date: July 8, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-related effects between men and women

NCT ID: NCT04381104 Recruiting - Pain Clinical Trials

Strategy to Cope Pain and Discomfort in Mammography

Start date: November 21, 2019
Phase: N/A
Study type: Interventional

Most of the women complain about the pain and discomfort during the mammography procedure. It is reported in the literature that most of the time these pain and discomfort are due to anxiety-related causes. During counseling before mammography scan, it was also observed that most of the women had a general belief that mammography is a very painful procedure and they have a negative perception about mammography. Thus, the Majority of pain seems due to anxiety-related issues. Studies also support this evidence and it is reported in the literature that most of the women avoid mammography scans due to this negative perception which causes delay and ultimately a late diagnosis. To validate the exact nature of pain and discomfort during mammography and to find out the strategy to cope with this anxiety-related pain and discomfort, there is a dire need for a study that can address this problem. Additionally, in our setup, most of the women who came for mammography are illiterate and belonged to the low socio-economic status. In these women, due to the negative perception, refusal or withdrawal rate is higher for mammography scans. A thorough literature search has revealed studies on this issue are scarce both nationally and internationally. In the current study, Paracetamol will be used as a possible intervention which is the safest premedication for reducing pain while achieving standard compression which is necessary for good image quality. Thus, this study can help develop a strategy to control mammography discontinuation due to pain and discomfort.

NCT ID: NCT04343807 Recruiting - Breast Cancer Clinical Trials

Effectiveness of Ultrasound Guided PECS Block on Opioid Consumption and Patient Satisfaction Through Adequate Pain Control Following Breast Cancer Surgery.

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Breast cancer is the most common and leading cause of cancer deaths among females worldwide. Patients undergoing modified radical mastectomy (MRM) are associated with moderate to severe acute postoperative pain and shoulder mobility restriction. This study aims to determine the effectiveness of ultrasound-guided PECS block for reducing opioid consumption, providing adequate postoperative pain management and improving patient satisfaction following breast cancer surgery.

NCT ID: NCT04307914 Recruiting - Pain Clinical Trials

Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases

FURTHER
Start date: March 10, 2020
Phase: N/A
Study type: Interventional

The FURTHER study aims to evaluate the effectiveness and cost-effectiveness of MR-HIFU (alone or in combination with EBRT) compared to EBRT alone, the standard-of-care, as a palliative treatment option to relieve CIBP. The FURTHER study consists of a multicenter, three-armed randomized controlled trial (FURTHER RCT) and a patient registry arm (FURTHER Registry), which will be performed in six hospitals in four European countries.

NCT ID: NCT04285112 Recruiting - Pain Clinical Trials

SPRINT: Signature for Pain Recovery IN Teens

SPRINT
Start date: September 28, 2020
Phase:
Study type: Observational

To identify biological and phenotypic prognostic markers of recovery vs. persistence of pain and functional disability in adolescents with chronic musculoskeletal pain.

NCT ID: NCT04278404 Recruiting - Hypertension Clinical Trials

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

POPS or POP02
Start date: March 5, 2020
Phase:
Study type: Observational

The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.

NCT ID: NCT04269239 Recruiting - Pain Clinical Trials

Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation

HH
Start date: April 30, 2021
Phase: N/A
Study type: Interventional

This study aims to evaluate behavioral interventions in conjunction with medical rehabilitation to promote functional health in patients recovering from orthopedic surgery. Half of the subjects in this study will be assigned to an intervention that meets with a study therapist to discuss implementing healthy habits. The other half of subjects will assigned to an intervention group that meets with a study therapists to discuss implementing healthy sleep habits. Both groups will undergo several physical and cognitive assessments.

NCT ID: NCT04268901 Recruiting - Pain Clinical Trials

VR to Reduce Pain/Anxiety During Painful Procedures

Start date: February 19, 2016
Phase: N/A
Study type: Interventional

This study aims to test the effectiveness of virtual reality (VR) as a non-pharmaceutical intervention to reduce pain and anxiety in children undergoing painful procedures in Phlebotomy, Radiology, Infusion, Orthopedics, Gastroenterology, and Immunology, amongst others, at CHLA, as measured by self- and proxy-report. Examples of the painful procedures include IV sticks, cast removals, allergy testing, and anorectal manometries.