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Pain clinical trials

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NCT ID: NCT05708586 Terminated - Pain Clinical Trials

Virtual Reality Decreases Child Anxiety and Pain as Well as Caregiver Anxiety and Pain Perception During Orthopaedic Clinic Office Procedures

Start date: December 8, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to demonstrate that the use of a virtual reality experience can decrease child and caregiver anxiety and pain for simple orthopaedic office procedures.

NCT ID: NCT05050123 Terminated - Pain Clinical Trials

Smartphone-based Virtual Reality Exposure and Standard Relaxation Training for Anxiety on an Inpatient Psychiatric Unit

Start date: October 5, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to compare a smartphone-based virtual reality exposure with standard relaxation training for anxiety and associated symptoms (including pain) on an inpatient psychiatric unit, and whether patients find it usable and beneficial.

NCT ID: NCT04941443 Terminated - Pain Clinical Trials

Methadone and Medication Abortion

Start date: October 4, 2021
Phase: Phase 4
Study type: Interventional

Pain has been recognized to be the most common and predictable side effect of medication abortion, causing significant distress associated with the process. Yet there is little known about the appropriate management of pain during this process, with no current evidence based recommendations for optimal analgesic regimens during the first trimester. The goal of this study is to evaluate the efficacy of oral methadone for pain control during medication abortion. The current medication regimen used to perform medication abortion is a dose of mifepristone (antiprogesterone) orally, followed by a dose of misoprostol (prostaglandin analogue) 24 to 72 hours later. Patients are prescribed a standard dose of ibuprofen 600-800mg tabs for pain control during the process. The investigators will conduct a non-randomized, pilot study with 25 patients evaluated at the Boston Medical Center family planning clinic at 10 weeks of gestation or less for medication abortion.

NCT ID: NCT04783532 Terminated - Pain Clinical Trials

Feasibility of Telehealth Mindfulness for Back Pain in the Emergency Department

Start date: March 5, 2021
Phase: N/A
Study type: Interventional

While guideline-directed nonpharmacological strategies for chronic low back pain are well established, optimal chronic pain management for emergency department patients has yet to be defined. Mindfulness interventions can be used for management of chronic conditions, yet are understudied as a primary approach for patients with chronic pain discharged from the emergency department. Currently, there is limited evidence examining whether an individual telehealth mindfulness intervention is a feasible and acceptable for these patients. This study will develop, pilot, and evaluate the feasibility and effects of an 8-session (12-week) telehealth mindfulness intervention for patients with an acute exacerbation of chronic low back pain

NCT ID: NCT04558840 Terminated - Pain Clinical Trials

Enhanced Recovery After Bilateral Reduction Mammaplasty

Start date: October 15, 2021
Phase: N/A
Study type: Interventional

This single-center, clinical trial is being conducted to determine whether non-narcotic pain regiments are as effective as narcotic-based regiments in reducing post-operative pain in patients undergoing breast reduction in the outpatient setting.

NCT ID: NCT04378062 Terminated - Pain Clinical Trials

Pain After Proximal Digital Amputation Prevention

PAPDAP
Start date: March 1, 2020
Phase: N/A
Study type: Interventional

Finger amputations are common and may be complicated by debilitating nerve pain. This study seeks to determine if nerve pain after digital amputation can be more effectively prevented with either of two new surgical techniques-targeted muscle reinnervation (TMR) or regenerative peripheral nerve interfaces (RPNI)-compared to standard treatment by traction neurectomy (TN).

NCT ID: NCT04356352 Terminated - Pain Clinical Trials

Lidocaine, Esmolol, or Placebo to Relieve IV Propofol Pain

Start date: September 9, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The primary hypothesis is that esmolol and lidocaine, when given without the use of a tourniquet, provide relief of propofol injection pain that is superior to placebo when assessed using the propofol pain scoring tool

NCT ID: NCT04319679 Terminated - Pain Clinical Trials

ESWT for UE Pain in Patients With Cervical Spinal Cord Injury

Start date: June 5, 2020
Phase: N/A
Study type: Interventional

This study aimed to investigate the efficacy and safety of extracorporeal shockwave therapy (ESWT) for upper extremity pain related to spasticity in patients with spinal cord injury.

NCT ID: NCT04313179 Terminated - Pain Clinical Trials

Music Therapy for Pain Management for Minor Procedures in Neonates.

Start date: April 9, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to assess the effectiveness and safety of music therapy as adjuvant therapy for pain management in newborns undergoing minor painful procedures. It is a prospective study and we plan to enroll 200 healthy full term newborns undergoing minor procedures (heel pricks). They will be randomly assigned to either control or music group. Those in music group will receive recorded Mozart lullaby music. Pain will be assessed using NIPS (Neonatal Infant Pain Scale) scoring tool. The potential benefit of the study would be identifying music a safe and efficient adjuvant therapy for pain management in newborns.

NCT ID: NCT04268810 Terminated - Clinical trials for Interstitial Cystitis

Prospective Trial Comparing Intravesical Chondroitin Sulphate 2% and DMSO in the Treatment of PBS/Interstitial Cystitis

Start date: March 2010
Phase: Phase 4
Study type: Interventional

Painful bladder syndrome/interstitial cystitis (PBS/IC)is a disease of unknown origin with a significant impact on the quality of life. Next to oral treatment with tricyclic antidepressants or pentosan polysulphate, intravesical treatment can be used as well. The purpose of this treatment is to restore the protective lining of the bladder that consists of glycan structures (GAG). Currently only dimethylsulfoxide (DMSO) is FDA approved for this. Several other compounds have been introduced. We want to compare a solution of chondroitin sulphate 2% with the standard DMSO solution. We will compare the patient perception of benefit,but also pain scores, quality of life and micturition diaries.