Clinical Trials Logo

Pain clinical trials

View clinical trials related to Pain.

Filter by:
  • Withdrawn  
  • Page 1 ·  Next »

NCT ID: NCT05671913 Withdrawn - Pain Clinical Trials

Scheduled Intranasal Ketamine

SINK
Start date: January 1, 2023
Phase: Early Phase 1
Study type: Interventional

The purpose of this research is to determine if scheduled intranasal ketamine effects opioid requirements in adult trauma patients with moderate to severe pain in the inpatient setting.

NCT ID: NCT05054595 Withdrawn - Pain Clinical Trials

Audio-Recorded vs. Nurse-Led Brief Mindfulness-Based Intervention

Start date: September 20, 2021
Phase: N/A
Study type: Interventional

This is a single-site, three-arm, parallel-group randomized clinical trial (RCT). The clinical effects of a nurse-led, very brief, preoperative mindfulness-based intervention for hip and knee replacement patients will be investigated relative to an audio-recorded very brief, preoperative mindfulness-based intervention delivered during the standard nurse consult and a nurse-led preoperative pain psychoeducation intervention during the standard nurse consult.

NCT ID: NCT05017584 Withdrawn - Pain Clinical Trials

ED90 of 0.75% Bupivacaine for Bilateral Tubal Ligation (BTL)

Start date: January 2023
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the dose of bupivacaine that provides effective pain management in 90% (ED90) of patients undergoing bilateral tubal ligation. This will guide anesthesiologists on the most effective dose to minimize intraoperative pain during this procedure. The goal is to make women as comfortable as possible when they undergo this procedure while also minimizing the amount of time they are required to remain in the hospital afterwards for monitoring.

NCT ID: NCT04991597 Withdrawn - Pain Clinical Trials

The Effects of Injection Site Cooling and Solution Buffering on Perceived Pain During Local Anesthesia Administration

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Participants will have local anesthesia administered to the palmar aspect of both forearms using 4 different injection methods in order to determine which method provides the best results in terms of perceived pain, overall comfort, and participant preference. Injection site cooling and solution buffering using a 3:1 ratio will be compared to the current standard, no injection site cooling and 9:1 solution buffering.

NCT ID: NCT04692389 Withdrawn - Pain Clinical Trials

Jalosome® Soothing Gel Efficacy Grade 2 or 3 Radiodermatitis.

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Testing the efficacy of the Jalosome® Soothing gel in 2 or 3 grade radiodermatitis healing in oncological patients. The investigators would like to know also the efficacy of the device on quality of life and pain.

NCT ID: NCT04662450 Withdrawn - Labor Pain Clinical Trials

Evaluation and Management of Parturients' Pain Intensity

Start date: September 2024
Phase: N/A
Study type: Interventional

The primary objective of this study is to examine the effects of Attentional Bias Modification (ABM) on the labor pain in parturients. One-third of the participants will undergo ABM training away from affective pain stimuli. One-third of the participants will undergo ABM training away from sensory pain stimuli. The rest of participants will be the control group.

NCT ID: NCT04613102 Withdrawn - Pain Clinical Trials

The Efficacy and Safety of 3% Cannabidiol (CBD) Cream in Patients With Epidermolysis Bullosa: A Phase II/III Trial

Start date: August 1, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

Epidermolysis bullosa (EB) is rare, devastating, and currently incurable genetic blistering disorders characterized by fragility of skin and mucosal membranes. Therapeutic options for EB are limited. Acute and chronic wounds cause pain, itching and infection, altering quality of life and impair wound healing. In absence of a cure, wound care is paramount to alleviate suffering. Anecdotal experience suggest that CBD application alleviates the pain and itching and improves wound healing by controlling the inflammatory process. We propose to undertake a phase II/III study exploring the safety, tolerability and efficacy of topical application of 3% Cannabidiol cream (CBD) on acute and chronic wounds affecting patients with EB. We are doing this trial to determine safety and tolerability of topical CBD cream in a cohort of RDEB patients with chronic wounds (phase II trial), and to evaluate the efficacy and safety of CBD cream in EB with acute and chronic wounds in promoting wound healing, decrease blister formation, pain, itching and improve overall quality of life (phase III trial)

NCT ID: NCT04595721 Withdrawn - Pain Clinical Trials

Comparison of Physical Versus Visual Distraction in the Reduction of Pain During Local Anesthesia

Start date: March 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to compare physical versus visual distractions to determine which technique reduces perceived pain better during local anesthesia injections.

NCT ID: NCT04530162 Withdrawn - Pain Clinical Trials

Prevention of Post Herpetic Neuralgia by Ultrasound Guided Single Nerve Block in the ED

Start date: October 1, 2021
Phase:
Study type: Observational

Herpes zoster causes significant morbidity on over 1 million Americans every year. Although the majority of herpes zoster pain will self-resolve within one week, a significant proportion of patients will develop postherpetic neuralgia (PHN), which is characterized by debilitating pain that persists more than three months after the initial symptoms. Nerve blocks have been previously studied as a method to control herpes zoster pain in outpatient pain clinics and inpatient settings. This study aims to investigate whether emergency department ultrasound guided nerve blocks can prevent PHN and effectively treat acute herpes zoster pain.

NCT ID: NCT04292808 Withdrawn - Pain Clinical Trials

Low Dose Methoxyflurane and Out-Patient Aesthetic Surgery and Facial Filler

Start date: July 2020
Phase: N/A
Study type: Interventional

The aim of the study is to generate real-world evidence on the effectiveness, safety and additional parameters of low dose methoxyflurane (PENTHROX®) in: aesthetic surgeries (eg. hair transplant, upper blepharoplasty, otoplasty, upper brow lift, and mentoplasty) and facial filler injections [eg. hyaluronic acid (HA) and Sculptra®] in an outpatient aesthetic practice. This will be an open-label study, with a total of 60 patients undergoing a planned outpatient aesthetic surgery or filler injection (30 patients in each group).