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Pain, Postoperative clinical trials

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NCT ID: NCT05145153 Recruiting - Postoperative Pain Clinical Trials

Incidence of Chronic Pain After Thoracic Surgery

Start date: September 28, 2021
Phase:
Study type: Observational

Thoracotomy and video-assisted thoracic surgery procedures are frequently performed in thoracic surgery. It is widely accepted that thoracotomy causes severe acute pain. This prolongs the discharge time of the patients, and increases the frequency of postoperative pulmonary complications and postoperative morbidity. Postoperative acute pain may cause chronic thoracotomy pain in the later period, and may adversely affect the quality of life of the patients. Video-assisted thoracic surgery (VATS) has become the standard procedure in minor and major lung surgeries. Postoperative pain is seen in patients undergoing VATS, although it is not as severe as after thoracotomy. As in thoracotomy, this affects the postoperative pulmonary complications and the discharge time of the patients. Likewise, this pain can cause chronic pain. In this study, it was aimed to analyze the symptoms of chronic pain in the 3rd and 6th months postoperatively in patients who had undergone thoracic surgery.

NCT ID: NCT05144828 Recruiting - Pain, Postoperative Clinical Trials

Efficacy of Intercostal CryoAnalgesia in Robotic Lung Resection

Start date: February 15, 2022
Phase: Phase 4
Study type: Interventional

This is a single center, single surgeon, prospective, randomized trial examining the addition of Cryo Nerve Block during robot assisted thoracoscopic anatomic lung resection surgery

NCT ID: NCT05141591 Recruiting - Anxiety Clinical Trials

Gender-specific Preoperative Anxiety Level and Postoperative Opioid Requirement After ENT Surgery.

Start date: November 11, 2021
Phase:
Study type: Observational

The study will be designed to investigate the impact of the preoperative anxiety level on postoperative opioid requirement during the PACU stay, in order to improve postoperative pain treatment in the long term after ENT surgery. The present study can contribute to improve postoperative pain management in patients in the field of ENT surgery, as new influencing parameters and risk factors may be discovered.

NCT ID: NCT05140499 Recruiting - Pain, Postoperative Clinical Trials

Liposomal Bupivacaine vs Continuous Nerve Catheters for Below the Knee Amputations

Start date: August 15, 2022
Phase: Phase 4
Study type: Interventional

Through this pilot prospective trial, we aim to obtain preliminary data investigating the effectiveness of perineural catheters and liposomal bupivacaine, both currently accepted as standard care at Maine Medical Center, for the management of post-limb amputation pain. We will use the data that we collect to inform the design of a larger, appropriately powered study.

NCT ID: NCT05136625 Recruiting - Post Operative Pain Clinical Trials

Sphenopalatine Ganglion Block and Pain Management in Neurosurgery

SpheNoPain
Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Post craniotomy pain is defined as headache developed up to 7 days from a craniotomy, not otherwise explained. A moderate to severe pain affects from 60 to 84% of patients. Sphenopalatine ganglion block has been successfully used in patients with chronic or acute headache, facial pain and for transsphenoidal pituitary and endoscopic sinus surgeries. There are evidences that sphenopalatine ganglion block reduces vegetative responses to skull pin closure. This study aim to investigate feasibility and efficacy of sphenopalatine ganglion block in reducing pain after a neurosurgical supratentorial craniotomy.

NCT ID: NCT05132595 Recruiting - Postoperative Pain Clinical Trials

Esketamine vs. Ketorolac for Prevention of Postoperative Pain and Cognitive Dysfunction After Total Knee Arthroplasty

Start date: November 30, 2021
Phase: N/A
Study type: Interventional

Purpose: To compare esketamine and ketorolac separately and in combination to prevent postoperative pain and cognitive dysfunction after total knee arthroplasty

NCT ID: NCT05131178 Recruiting - Cesarean Section Clinical Trials

Post-operative Cesarean Trial of Pain Control

Start date: November 7, 2021
Phase: N/A
Study type: Interventional

This study plans to learn more about postoperative pain management after cesarean deliveries (C-sections). As a part of standard of care, the Children's Hospital Colorado's Colorado Fetal Care Center (CFCC) follows the standard Enhanced Recovery After Cesarean (ERAC) guidelines to manage pain following C-section delivery. In addition, the CFCC uses an FDA approved medical device called the ON-Q ® Pump, which continuously delivers local anesthetic medication to control pain in the area of your procedure. The local anesthetic used is bupivacaine, which is FDA approved for use to control local pain after C-sections. The CFCC has found a significant reduction in opioid use after adopting both of these procedures. The study aims to determine if the ERAC protocol or ON-Q ® Pump continuous infusion is responsible for lower opioid use by comparing bupivacaine (treatment) versus saline (placebo) groups.

NCT ID: NCT05120076 Recruiting - Pain Clinical Trials

Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Periacetabular Osteotomy

Start date: July 16, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the effect of Dexamethasone on postoperative pain and nausea after periacetabular osteotomy.

NCT ID: NCT05117307 Recruiting - Pain Clinical Trials

Comparison of Transversalis Fascia Plane Block and Erector Spinae Plane Blocks in Cesarean Section

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Cesarean section is one of the most common major surgical procedures performed worldwide,, Post-cesarean analgesia should provide adequate pain control while allowing the mother to remain active to meet the needs of the baby. Insufficient analgesia after cesarean section may be associated with acute postoperative pain, chronic pain, higher opioid consumption, delayed functional capacity, and postpartum depression. Techniques such as neuraxial techniques, oral and intravenous agents, wound infiltration, and behavioral therapy can be used in the treatment of post-cesarean pain pain. In addition, Transversus abdominis plane block (TAP), Quadratus Lumborum block (QLB), Erector Spina block (ESP), Transversalis Fascia plane block (TFP) are used safely under ultrasound guidance. In this study, it was aimed primarily to examine the effects of TFP and ESP blocks on pain scores, and secondarily to evaluate analgesic consumption.

NCT ID: NCT05117034 Recruiting - Anesthesia Clinical Trials

Pre-emptive Intravenous Morphine for Acute Post-craniotomy Pain.

Start date: February 16, 2022
Phase: N/A
Study type: Interventional

We propose a double-blind randomized controlled trial to evaluate the effect of intravenously administered morphine at surgery conclusion on acute postoperative pain in patients recovering from craniotomy surgery. Participating adults having craniotomy surgery will be randomized in a 1:1 ratio to intraoperative intravenous administration of 0.08 mg/kg morphine at dura closure, or a matching placebo.