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Pain, Postoperative clinical trials

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NCT ID: NCT06459739 Completed - Anesthesia Clinical Trials

Effect of Sacral Erector Spinae Plane Block on Hemorrhoid and Pilonidal Sinus Surgery

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Introduction: This study investigated the efficacy of sacral erector spinae plane block (ESPB) for managing postoperative pain and reducing opioid consumption in patients undergoing hemorrhoid and pilonidal sinus (PS) surgery.

NCT ID: NCT06457880 Completed - Pain, Postoperative Clinical Trials

PENG Block vs FNB + ONB in Patients Undergoing Hip Fracture Surgery With Contraindications to Neuraxial Anesthesia

PENG/FNB+ONB
Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to demonstrate the efficacy of PENG block as the main anesthetic technique to manage perioperative analgesia for hip fracture surgery compared to femoral and obturator nerve block in patients with contraindications to spinal anesthesia.

NCT ID: NCT06451705 Completed - Pain, Postoperative Clinical Trials

Pecs Block vs Local Infiltration in Mastectomy

PBLIM
Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Studied the comparison between PECS II block and LIA on pain intensity, opioid requirements, RNL, and postoperative IL-6 levels in MRM patients.

NCT ID: NCT06433713 Completed - Postoperative Pain Clinical Trials

Effect of Intraoperative Intravenous Lidocaine on Postoperative Pain and Return of Bowel Function After Cesarean Sections

Start date: December 1, 2023
Phase: Phase 2
Study type: Interventional

Postoperative discomfort is a frequently seen adverse event after to caesarean operation. Early mobilization and bonding of the mother and her infant are typically impacted by this phenomenon. Nevertheless, the current state of postoperative analgesia and recovery remains inadequate in clinical settings. In the context of major abdominal surgery, opioids are often regarded as the preferred postoperative analgesic. Nevertheless, they possess adverse side effects that might impact the process of recuperation after surgery. These symptoms include nausea and vomiting, decreased bowel movement, and shallow breathing. One additional challenging consequence after surgery is the delayed restoration of bowel function, which has the potential to extend the duration of hospitalization and impede the initiation of oral feeding, resulting in gaseous colonic distension. The administration of lidocaine infusion has been shown to possess analgesic, anti-hyperalgesic, and anti-inflammatory characteristics. The use of intravenous lidocaine after surgery is postulated to have the dual effect of mitigating postoperative pain and expediting the resumption of bowel movements. Recent studies have shown that the administration of intravenous lidocaine, either as a single dosage or by continuous infusion, may have potential advantages in maintaining gastrointestinal motility and exerting an impact on biochemical pain mechanisms. However, the literature presents contradictory data about the effectiveness of lidocaine in providing sufficient postoperative pain relief and reducing postoperative ileus. Consequently, this study was conducted and aimed to assess the effect of intravenous intraoperative lidocaine on postoperative pain and early return of bowel function following elective caesarean section. This randomized clinical trial was conducted at Obstetrics and Gynecology Department, Faculty of Medicine, Cairo University Hospitals from August till December 2023. A total of 60 pregnant women underwent elective caesarean section were enrolled and randomized into two groups; experimental group who received IV infusion of lidocaine starting with skin incision, which was maintained until skin closure and control group who received 0.9% normal saline at the same rate as that described in the experimental group. Both groups were compared as regard total operative time, medications given, start-stop time of the study drug infusion, and degree of pain using visual analogue scale, need for analgesics, time for first healing of normal intestinal sounds and time to first flatus and symptoms of lidocaine toxicity were recorded.

NCT ID: NCT06433089 Completed - Nerve Block Clinical Trials

Postoperative Pain for Patients After TA-BSM

Start date: April 1, 2023
Phase:
Study type: Observational

To retrospectively analyze the intraoperative and postoperative status of patients with hypertrophic cardiomyopathy undergoing TA-BSM, and to estimate whether paravertebral nerve block can improve postoperative pain for these patients.

NCT ID: NCT06427551 Completed - Anesthesia Clinical Trials

Volume Effect in Peng Block for Total Hip Replacement

volupeng
Start date: January 1, 2022
Phase:
Study type: Observational

This study is to investigate whether a different volume of ropivacaine, with the same prescribed dosage based on body weight, can affect block efficacy, duration and side effects in the first 24 hours postoperatively.

NCT ID: NCT06425601 Completed - Postoperative Pain Clinical Trials

A Comparison of Silicone Versus Polyvinylchloride (PVC) Drains Following VATS Lobectomy

Start date: September 30, 2020
Phase: N/A
Study type: Interventional

The goal of this prospective randomized clinical trial is to compare the impact of the chest tube type on pain, chest drainage efficacy and early postoperative outcome following VATS lobectomy for lung cancer. The main questions it aims to answer are: - silicone chest drains are less painful compared to standard PVC drains? - is there any difference in chest drainage efficacy and short term outcome between the two groups? Researchers will compare silicone chest drain group with PVC chest drain group to see if there is any difference in postoperative pain, chest drainage efficacy and short term outcome.

NCT ID: NCT06412380 Completed - Postoperative Pain Clinical Trials

Influence of Insertion Torque and Bone Type on Post-operative Pain

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

The objectives of this clinical study were to assess the effect of different ITs and bone types on POP levels and survival rates and to investigate the effect of different patient- and site-related factors on POP levels and survival rates.

NCT ID: NCT06403293 Completed - Post Operative Pain Clinical Trials

Influence of Sonic Activation of Root Sealers on Post-Operative Pain

Start date: January 16, 2023
Phase: N/A
Study type: Interventional

Aim: This clinical study aims to compare post-operative pain after single-visit root canal treatment of teeth with asymptomatic apical periodontitis using epoxy-resin based AH Plus and calcium silicate based Endosequence BC sealers with or without sonic activation. Materials and Methods: The study included 72 individuals having one first or second mandibular premolar tooth with asymptomatic apical periodontitis. They were randomly divided into 4 groups according to the root canal sealer (AH Plus or Endosequence BC) and activation protocol (sonic activation or non-activation) (n=18). Participants were ask to rate their post-operative pain intensity on a NRS scale as none, minimal, moderate, or severe after 24 h, 48 h, 72 h and 7 days following treatment. Patients were also asked to record the number of prescribed analgesic medication tablets (ibuprofen 400 mg) taken. The collected data were statistically analyzed at 0.05 significance level.

NCT ID: NCT06387849 Completed - Post-operative Pain Clinical Trials

Aromatherapy Effect on Pain and Anxiety After C-section

Start date: April 21, 2023
Phase: N/A
Study type: Interventional

A prospective randomized triple blinded study conducted in the obstetrics gynecology department of Ben Arous hospital over a period of four months and 10 days between April 2023 and August 2023. The aim of this study was to evaluate the effectiveness of lavender aromatherapy on postoperative pain and anxiety after cesarean section under spinal anesthesia in Tunisian women.