Study of Children's Activity and Nutrition (SCAN)

Obesity Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00005178
• Other study ID #: 1056
• Secondary ID: R01HL035073
• Status: Completed
• Phase: N/A
• First received: May 25, 2000
• Last updated: December 21, 2015
• Start date: September 1985
• Est. completion date: August 1991

Study information

• Verified date: December 2000
• Source: Georgia Regents University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Observational

Clinical Trial Summary

In the first study, to identify children at high and low risk for cardiovascular disease and study their nutritional and physical activity behaviors as they relate to cardiovascular disease. In the second study, to make yearly assessments over a four year period of diet and physical activity among children and their parents. The initial effort redefined and retested methods to collect data on dietary intake and activity levels of young children.

Description:

BACKGROUND:

In the past several decades, relationships between various lifestyle behaviors and the development of cardiovascular risk factors have been identified. Nutritional status/eating behaviors and physical activity patterns both directly and indirectly are related to the development of coronary heart disease. For example, obesity, which may be a result of both eating and physical activity behaviors, greatly increases the risk of hypertension, hyperlipidemia, and diabetes mellitus, placing the individuals at greater risk for coronary heart disease. Dietary factors such as composition in fatty acids and cholesterol, composition in vegetable protein and complex carbohydrates, caloric excess and a high intake of salt also are related to the development of risk of coronary heart disease.

Physical activity in adults has also been correlated with coronary heart disease. Epidemiological research has demonstrated that increased physical activity is associated with reduced risk of myocardial infarctions. Regular physical exercise has been shown to have beneficial effects on relative weight and obesity and may act indirectly to beneficially affect hypertension, hypertriglyceridemia and glucose intolerance and raise HDL cholesterol levels. However, in 1985 when SCAN was initiated, little information was available concerning the development of nutritional status/eating behaviors and routine physical activity patterns in children.

Various psychosocial factors have been associated with increased risk of coronary heart disease. Among these factors are behavioral characteristics such as type A behaviors and coping styles to stressors. However, relatively little was known in 1985 concerning the development of such characteristics in children and when these characteristics became associated with risk of cardiovascular disease.

SCAN initiated on the recommendations of the Preventive Cardiology Branch Task Force Group in the Five Year Forward Plan 1982-1987, the Conference on School Health Education Research in the Heart, Lung, and Blood Areas, and the Clinical Applications and Prevention Advisory Committee of the National Heart, Lung, and Blood Institute. A Request for Applications was released in October 1984. In 1985, six grants were awarded as part of the Study of Children's Activity and Nutrition (SCAN).

DESIGN NARRATIVE:

There were six projects supported by the SCAN program. They did not follow a common protocol but were basically similar.

Medical College of Georgia: Five hundred and one Black and white children were followed over a four year period for food intake behavior, physical activity and fitness, anthropometric measurements, blood lipids and lipoproteins, heart rate and blood pressure, and psychologic characteristics associated with coronary heart disease.

West Virginia University: Two hundred and eight predominantly white children of adults followed since adolescence in the Bourbon County Study were members of this cohort. Children participated in cardiovascular fitness tests, and underwent blood pressure measurements, and serum lipid determinations. The effects of television-viewing, child-rearing patterns, exercise, and nutrition-related knowledge and attitudes were assessed over a four year period.

Columbia University: Seven hundred and ninety-four primarily Hispanic children and their parents were followed for four years to determine the extent to which diet and physical activity predict coronary heart disease risk. Cross sectional and longitudinal analyses were performed.

Georgetown University: Five hundred and seventy Black children were followed for the influence of the risk status of an older sibling and day care versus home care on nutrient intake and physical activity. Eating events were videotaped, activity levels were recorded, and measurements were obtained on height, weight, cholesterol, blood pressure, and skinfold thickness. Dietary recalls and nutrition knowledge surveys were obtained.

University of Massachusetts: In the Framingham Children's Study, one hundred children who were direct descendents of Framingham Heart Study participants were followed for four years. Measurements included height, weight, skinfold thickness, lipid profiles, heart rate and activity monitoring, and assessment of dietary intake four times per year.

Memphis State University: Six hundred and sixty-three children and their parents were assessed for food intake, physical activity, and parent-child interactions related to food intake and exercise. Anthropometric and cardiovascular data were also collected every four months for four years.

Two of the studies were renewed in FY 1992 and again in FY 1996. See the Framingham Children's Study and the Children's Activity and Nutrition III.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. completion date: August 1991
• Accepts healthy volunteers: No
• Gender: Male
• Age group: N/A to 100 Years
• Eligibility: No eligibility criteria

Study Design

N/A

Related Conditions & MeSH terms

• Cardiovascular Diseases
• Coronary Artery Disease
• Coronary Disease
• Coronary Heart Disease Risk Reduction
• Heart Diseases
• Hypercholesterolemia
• Hypertension
• Myocardial Ischemia
• Obesity

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Georgia Regents University	National Heart, Lung, and Blood Institute (NHLBI)

References & Publications (47)

Arensman FW, Treiber FA, Gruber MP, Strong WB. Exercise-induced differences in cardiac output, blood pressure, and systemic vascular resistance in a healthy biracial population of 10-year-old boys. Am J Dis Child. 1989 Feb;143(2):212-6. — View Citation

Basch CE. Focus group interview: an underutilized research technique for improving theory and practice in health education. Health Educ Q. 1987 Winter;14(4):411-48. Review. — View Citation

Cohen R, Klesges RC, Summerville M, Meyers AW. A developmental analysis of the influence of body weight on the sociometry of children. Addict Behav. 1989;14(4):473-6. — View Citation

DeLozier M, Gutin B, Wang J, Zybert P, Basch C, Rips J, Shea S, Contento I, Irigoyen M, Pierson R: Bio-Impendance Derived Estimates of Body Composition in 4-8 Years Olds. Medicine and Science in Sports and Exercise, 20:S31, 1988

DeLozier M, Rips J, Gutin B, and Basch C: Strategies and Techniques for Conducting Treadmill Tests in Preschool-Age Children, J Phys Educ, Recreat and Dance, forthcoming, 1988

DuRant RH, Baranowski T, Rhodes T, Gutin B, Thompson WO, Carroll R, Puhl J, Greaves KA. Association among serum lipid and lipoprotein concentrations and physical activity, physical fitness, and body composition in young children. J Pediatr. 1993 Aug;123(2):185-92. — View Citation

Eck LH, Klesges RC, Hanson CL. Recall of a child's intake from one meal: are parents accurate? J Am Diet Assoc. 1989 Jun;89(6):784-9. — View Citation

Ellison RC. Give diet a chance in lowering cholesterol levels. Arch Intern Med. 1988 May;148(5):1017-9. — View Citation

Ellison RC: Dangers of Screening for Hyperlipidemia in Children (letter to the editor). N Engl J Med, 314:1579-1580, 1986

Gutin B, Alejandro D, Duni T, Segal K, Phillips GB. Levels of serum sex hormones and risk factors for coronary heart disease in exercise-trained men. Am J Med. 1985 Jul;79(1):79-84. — View Citation

Gutin B, Gutin C: Obesity Prevention and Exercise in Countries Undergoing Technological Development. Physician & Sportsmedicine, 14(10):197-201, 1986

Gutin B, Mayers M, Levy J, Herman M: Physiologic & Echocardiographic Studies of Age-Group Runners. In: Brown E (Ed) Competitive Sports for Children & Youths. Champaign: Human Kinetics, 1987

Gutin B: Basic Principles of Training and Fitness. Contemporary OB/GYN. Special Issue on The Active Women, May 1985

Hulse E, Strong WB. Preparticipation evaluation for athletics. Pediatr Rev. 1987 Dec;9(6):173-82. Review. — View Citation

Klem ML, Klesges RC, Bene CR, Mellon MW. A psychometric study of restraint: the impact of race, gender, weight and marital status. Addict Behav. 1990;15(2):147-52. — View Citation

Klem ML, Klesges RC. Competition in a minimal-contact weight-loss program. J Consult Clin Psychol. 1988 Feb;56(1):142-4. — View Citation

Klesges LM, Klesges RC. The assessment of children's physical activity: a comparison of methods. Med Sci Sports Exerc. 1987 Oct;19(5):511-7. — View Citation

Klesges RC, Eck LH, Hanson CL, Haddock CK, Klesges LM. Effects of obesity, social interactions, and physical environment on physical activity in preschoolers. Health Psychol. 1990;9(4):435-49. — View Citation

Klesges RC, Eck LH, Isbell TR, Fulliton W, Hanson CL. Smoking status: effects on the dietary intake, physical activity, and body fat of adult men. Am J Clin Nutr. 1990 May;51(5):784-9. — View Citation

Klesges RC, Haddock CK, Eck LH. A multimethod approach to the measurement of childhood physical activity and its relationship to blood pressure and body weight. J Pediatr. 1990 Jun;116(6):888-93. — View Citation

Klesges RC, Hanson CL, Eck LH, Durff AC. Accuracy of self-reports of food intake in obese and normal-weight individuals: effects of parental obesity on reports of children's dietary intake. Am J Clin Nutr. 1988 Nov;48(5):1252-6. — View Citation

Klesges RC, Klem ML, Bene CR. Effects of dietary restraint, obesity, and gender on holiday eating behavior and weight gain. J Abnorm Psychol. 1989 Nov;98(4):499-503. — View Citation

Klesges RC, Klem ML, Hanson CL, Eck LH, Ernst J, O'Laughlin D, Garrott A, Rife R. The effects of applicant's health status and qualifications on simulated hiring decisions. Int J Obes. 1990 Jun;14(6):527-35. — View Citation

Klesges RC, Klesges LM, Brown G, Frank GC. Validation of the 24-hour dietary recall in preschool children. J Am Diet Assoc. 1987 Oct;87(10):1383-5. — View Citation

Klesges RC, Meyers AW, Klesges LM, La Vasque ME. Smoking, body weight, and their effects on smoking behavior: a comprehensive review of the literature. Psychol Bull. 1989 Sep;106(2):204-30. Review. — View Citation

Michela JL, Contento IR. Cognitive, motivational, social, and environmental influences on children's food choices. Health Psychol. 1986;5(3):209-30. — View Citation

Mizes JS, Klesges RC. Validity, reliability, and factor structure of the Anorectic Cognitions Questionnaire. Addict Behav. 1989;14(5):589-94. — View Citation

Musante L, Treiber FA, Strong WB, Levy M. Family history of hypertension and cardiovascular reactivity to forehead cold stimulation in black male children. J Psychosom Res. 1990;34(1):111-6. — View Citation

Musante L, Treiber FA, Strong WB, Levy M. Individual and cross-spouse correlations of perceptions of family functioning, blood pressure and dimensions of anger. J Psychosom Res. 1990;34(4):393-9. — View Citation

Myers RJ, Klesges RC, Eck LH, Hanson CL, Klem ML. Accuracy of self-reports of food intake in obese and normal-weight individuals: effects of obesity on self-reports of dietary intake in adult females. Am J Clin Nutr. 1988 Nov;48(5):1248-51. — View Citation

Segal KR, Gutin B, Albu J, Pi-Sunyer FX. Thermic effects of food and exercise in lean and obese men of similar lean body mass. Am J Physiol. 1987 Jan;252(1 Pt 1):E110-7. — View Citation

Segal KR, Gutin B, Nyman AM, Pi-Sunyer FX. Thermic effect of food at rest, during exercise, and after exercise in lean and obese men of similar body weight. J Clin Invest. 1985 Sep;76(3):1107-12. — View Citation

Segal KR, Gutin B, Presta E, Wang J, Van Itallie TB. Estimation of human body composition by electrical impedance methods: a comparative study. J Appl Physiol (1985). 1985 May;58(5):1565-71. — View Citation

Shea S, Basch CE, Irigoyen M, Zybert P, Rips JL, Contento I, Gutin B. Failure of family history to predict high blood cholesterol among hispanic preschool children. Prev Med. 1990 Jul;19(4):443-55. — View Citation

Shea S, Basch CE, Zybert P, Rips J, Contento I, Gutin B, Irigoyen M. Screening using National Cholesterol Education Program guidelines in a population of urban Hispanic mothers. Prev Med. 1989 Nov;18(6):824-32. — View Citation

Strong WB (Ed): In: The Pediatrician of the 90's. Biomedical Information Corporation, 1988

Strong WB, Dennison BA. Pediatric preventive cardiology: atherosclerosis and coronary heart disease. Pediatr Rev. 1988 Apr;9(10):303-14. Review. — View Citation

Strong WB, Wilmore JH: Unfit Kids: An Office-Based Approach to Physical Fitness. Contemp Pediatr, 4:33-48, 1988

Strong WB. Physical activity and children. Circulation. 1990 May;81(5):1697-701. Review. — View Citation

Strong WB. So what's good about sports? Am J Dis Child. 1988 Feb;142(2):143. — View Citation

Treiber FA, Mabe PA 3rd, Riley W, Carr T, Levy M, Thompson W, Strong WB. Assessment of children's Type A behavior: relationship with negative behavioral characteristics and children and teacher demographic characteristics. J Pers Assess. 1989 Winter;53(4):770-82. — View Citation

Treiber FA, Musante L, Braden D, Arensman F, Strong WB, Levy M, Leverett S. Racial differences in hemodynamic responses to the cold face stimulus in children and adults. Psychosom Med. 1990 May-Jun;52(3):286-96. — View Citation

Treiber FA, Musante L, Hartdagan S, Davis H, Levy M, Strong WB. Validation of a heart rate monitor with children in laboratory and field settings. Med Sci Sports Exerc. 1989 Jun;21(3):338-42. — View Citation

Treiber FA, Musante L, Strong WB, Levy M. Racial differences in young children's blood pressure. Responses to dynamic exercise. Am J Dis Child. 1989 Jun;143(6):720-3. — View Citation

Weber JM, Klesges RC, Klesges LM. Dietary restraint and obesity: their effects on dietary intake. J Behav Med. 1988 Apr;11(2):185-99. — View Citation

Williams E, Klesges RC, Hanson CL, Eck LH. A prospective study of the reliability and convergent validity of three physical activity measures in a field research trial. J Clin Epidemiol. 1989;42(12):1161-70. — View Citation

Witschi JC, Capper AL, Hosmer DW Jr, Ellison RC. Sources of sodium, potassium, and energy in the diets of adolescents. J Am Diet Assoc. 1987 Dec;87(12):1651-5. — View Citation

* Note: There are 47 references in all — Click here to view all references