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Neuropathic Pain clinical trials

View clinical trials related to Neuropathic Pain.

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NCT ID: NCT06071936 Recruiting - Pain Clinical Trials

Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy

Start date: November 2, 2023
Phase: Phase 3
Study type: Interventional

Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates the efficacy and tolerability of the THC-focused nano endocannabinoid system modulator AP707 in patients with chronic pain disorders due to traumatic or post-operative peripheral neuropathy. Patients receive AP707 or placebo over the course of 14 weeks as an add-on to the standard of care. Changes in pain intensity, quality of life and sleep and others measures are monitored through different scales to assess the efficacy of AP707 in patients with chronic pain due to traumatic or post-operative peripheral neuropathy.

NCT ID: NCT06044584 Recruiting - Neuropathic Pain Clinical Trials

Unveiling Physiological and Psychosocial Pain Components With an Artificial Intelligence Based Telemonitoring Tool

pAIn-sense
Start date: August 29, 2023
Phase:
Study type: Observational

The pAIn-sense study aims to revolutionize the monitoring and treatment of chronic pain, a major health concern that significantly impacts psychological well-being and quality of life. Traditional approaches to pain management face challenges like unspecific drug use and high healthcare costs, and they often leave patients dissatisfied. PAIn-sense aims at comprehensively understanding pain from both physical and emotional perspectives. To accomplish this, the study will employ advanced Artificial Intelligence (AI) techniques and wearable sensing technology. The study aims to monitor patients continuously, during both day and night activities, to gather a multidimensional set of data on their physiological, psychosocial, and pain conditions.

NCT ID: NCT06023706 Recruiting - Neuropathic Pain Clinical Trials

Study Evaluating the Analgesic Efficacy of Capsaicin 8% Patches in Chronic Coccygodynia.

CAPSACOX
Start date: November 8, 2023
Phase: Phase 3
Study type: Interventional

The primary objective is to demonstrate the analgesic effect at day 60 of 8% capsaicin patch (Qutenza) for the treatment of patients with coccygodyinia.

NCT ID: NCT06019325 Recruiting - Breast Cancer Clinical Trials

Rhomboid Intercostal Plane Block on Chronic Pain Incidence and Acute Pain Scores After Mastectomy

Start date: September 7, 2023
Phase: N/A
Study type: Interventional

Rhomboid intercostal block is used to block lateral cutaneous branches of intercostal nerves between T3 and T9 dermatomes. RIB has been reported to be successful in attenuating acute pain following breast surgeries. However, it's effect on chronic pain has not been evaluated yet. The primary hypothesis of the study is that the incidence of chronic pain of the patients who will receive Rhomboid intercostal block (RIB) following breast cancer surgery will be lower than the patients who will receive no block intervention at the postoperative 3rd month. The secondary hypothesis is that the incidence ofchronic pain of the patients who will receive Rhomboid intercostal block (RIB) following breast cancer surgery will be lower than the patients who will receive no block intervention at the postoperative 6th month. An other secondary hypothesis is that the total BPI-SF scores will be lower in the RIB group than control group at the postoperative 3rd and the 6th months.

NCT ID: NCT06010251 Recruiting - Clinical trials for Spinal Cord Injuries

Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain

Start date: October 17, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effectiveness of bodily illusions combined with transcranial direct current stimulation (tDCS) on neuropathic pain symptoms and sensory functions in participants with spinal cord injury (SCI) and neuropathic pain.

NCT ID: NCT05998369 Recruiting - Chronic Pain Clinical Trials

Empowered Relief for Youth

ER-Y
Start date: August 9, 2023
Phase: N/A
Study type: Interventional

The purpose of this pilot study is to examine the feasibility and preliminary efficacy of Empowered Relief for Youth with chronic pain (ER-Y). ER-Y is a single-session pain management class for youth focused on pain science education and teaching self-regulatory skills for pain management based on the evidence-based adult ER class. Feasibility and acceptability of ER-Y will be assessed post-class. Preliminary efficacy will be assessed by administering surveys at baseline, 4-weeks, 8-weeks, and 12-weeks post class.

NCT ID: NCT05997979 Recruiting - Chronic Pain Clinical Trials

Analgesic Effectiveness of Capsaicin 8% Cutaneous Patch in Children

CAPSAPED
Start date: March 5, 2024
Phase: Phase 2
Study type: Interventional

This study concerns children aged to 12 to 17-years with local chronic neuropathic pain after trauma or surgery. It is a multicentric randomized controlled superiority trial in parallel arms : - experimental arm: Capsaicin 8% cutaneous patch - controlled arm : Hydrocolloid dressing Treatment with capsaicin application is realized at baseline, and repeated 3 months after the first patch application if needed. Tolerance is assessed during each application and by phone call in following days until stop of cold need. Efficacy is assessed monthly by clinical consultation until the end of the study (month 4).

NCT ID: NCT05984329 Recruiting - Neuropathic Pain Clinical Trials

Tonic Versus Burst DR(TM) Epidural Motor Cortex Stimulation for Neuropathic Pain

Start date: July 15, 2022
Phase:
Study type: Observational

Epidural stimulation of the primary motor cortex (PMC) is indicated for the relief of neuropathic pain refractory to pharmacological treatment.

NCT ID: NCT05975281 Not yet recruiting - Neuropathic Pain Clinical Trials

Neuropathic Pain Symptoms in Arthritis

Start date: July 27, 2023
Phase:
Study type: Observational

It was aimed to compare neuropathic pain symptoms in hand osteoarthritis and rheumatoid arthritis.

NCT ID: NCT05968664 Not yet recruiting - Chronic Pain Clinical Trials

Novel Stimulation Patterns to Improve the Effectiveness of Spinal Cord Stimulation

Start date: January 2024
Phase: N/A
Study type: Interventional

The goal of this study is to compare pain outcomes achieved by spinal cord stimulation (SCS) using time varying stimulation patterns with pain outcomes achieved by current standard of care SCS.