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Lung Neoplasm clinical trials

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NCT ID: NCT05596760 Recruiting - Quality of Life Clinical Trials

Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers

PICSI-M
Start date: September 11, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to improve communication among clinicians, patients with memory problems, and their family members. We are testing a way to help clinicians have better conversations to address patients' goals for their healthcare. To do this, we created a simple, short guide called the "Jumpstart Guide." The goal of this research study is to show that using this kind of guide is possible and can be helpful for patients and their families. Patients' clinicians may receive a Jumpstart Guide before the patient's clinic visit. Researchers will compare patients whose clinician received a Jumpstart Guide to patients whose clinician did not receive a guide to see if more patients in the Jumpstart Guide group had conversations about the patient's goals for their healthcare. Patients and their family members will also be asked to complete surveys after the visit with their clinician.

NCT ID: NCT05592626 Recruiting - Neoplasms Clinical Trials

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

START-001
Start date: January 4, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent administered intravenously in participants with advanced solid tumors that are antigen-rich.

NCT ID: NCT05319886 Recruiting - Lung Cancer Clinical Trials

Observational Study of the Efficacy and Safety of Anlotinib Combined With Penpulimab in Elderly Lung Cancer Patients

AP
Start date: May 16, 2022
Phase:
Study type: Observational [Patient Registry]

This prospective observational study will evaluate the efficacy and safety of anlotinib in combination with Penpulimab in elderly patients with lung cancer. Data will be collected from each patient at baseline and after 4-6 cycles of therapy.

NCT ID: NCT05078918 Recruiting - Lung Cancer Clinical Trials

Comprehensive Care Program for Their Return to Normal Life Among Lung Cancer Survivors

Start date: September 8, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to develop a comprehensive care program for their return to normal life and community among lung cancer survivors and evaluate the effectiveness of the program.

NCT ID: NCT05046067 Recruiting - Lung Neoplasm Clinical Trials

Feasibility Study of Anatomical Modeling for Image Guided Thoracic Surgery

Start date: September 16, 2020
Phase: N/A
Study type: Interventional

This clinical trial assesses the feasibility of creating a 3 dimensional (D) model of the lung and lung nodule(s) from computed tomography (CT) scan images performed during lung surgery. Unlike solid organs (like the kidney, brain, and liver), the lung changes shape (they inflate when a person breathe in and collapse when they breathe out). This makes it difficult to predict where, exactly, the tumor(s) will be on the lungs during surgery. A 3D model may help surgeons better predict where the location of the tumor(s) will be during surgery.

NCT ID: NCT04755478 Recruiting - Lung Cancer Clinical Trials

LUS to Assess Lung Injury After Lung Lobectomy

OPEN THORUS
Start date: January 28, 2021
Phase:
Study type: Observational

The purpose of the study is to assess whether lung ultrasound is able to detect lung injury after lung resection surgery.

NCT ID: NCT04677309 Recruiting - Lung Cancer Clinical Trials

LUS to Assess Lung Injury After Lung Resection

THORUS
Start date: December 20, 2020
Phase:
Study type: Observational

The purpose of the study is to assess whether lung ultrasound is able to detect lung injury after lung resection surgery.

NCT ID: NCT04490421 Recruiting - Clinical trials for Small Cell Lung Cancer

Camrelizumab Combined With Apatinib, Etoposide and Cisplatin Treat Small-cell Lung Cancer.

Start date: August 1, 2020
Phase: Phase 3
Study type: Interventional

Small cell lung cancer is a highly malignant tumor, and its first-line treatment has not broken through platinum-containing dual-drug chemotherapy in the past 30 years. Because small cell lung cancer has the characteristics of easy resistance after first-line chemotherapy, increased difficulty in treatment after resistance, and poor efficacy of second-line treatment, how to formulate a plan that can control tumor progression to the greatest extent has become a hot issue in recent research. Recently, immunotherapy and targeted therapy have made breakthrough progress in small cell lung cancer, but its efficacy still needs to be further improved. As immune combined chemotherapy combined with targeted therapy first achieved good results in other tumors, this study aims to explore a longer disease-free survival time and higher overall survival rate of patients with small cell lung cancer through immunotherapy combined with targeted therapy combined with chemotherapy. Program to bring new hope to patients. At the same time, this study will evaluate the safety of the program, explore the prognostic indicators that may exist in the treatment, and provide new inspiration for subsequent patient selection.

NCT ID: NCT04075305 Recruiting - Breast Cancer Clinical Trials

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

MOMENTUM
Start date: February 1, 2019
Phase:
Study type: Observational [Patient Registry]

The Multi-OutcoMe EvaluatioN of radiation Therapy Using the Unity MR-Linac Study (MOMENTUM) is a multi-institutional, international registry facilitating evidenced based implementation of the Unity MR-Linac technology and further technical development of the MR-Linac system with the ultimate purpose to improve patients' survival, local, and regional tumor control and quality of life.

NCT ID: NCT03765775 Recruiting - Clinical trials for Non-small Cell Lung Cancer

Anlotinib Plus Sintilimab for NSCLC Patients With First-generation EGFR-TKIs Drug Resistance Along With T790M Negative

Start date: November 20, 2018
Phase: Phase 2
Study type: Interventional

This is an efficacy and safety study of Anlotinib combined with Sintilimab (IBI 308) in participants with advanced or metastatic non-small cell lung cancer (NSCLC) who have received first-generation EGFR-TKIs resistance along with T790M negative.