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Hyperlipidemias clinical trials

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NCT ID: NCT03643705 Completed - Hypertension Clinical Trials

A Nurse-led Intervention to Extend the HIV Treatment Cascade for Cardiovascular Disease Prevention

EXTRA-CVD
Start date: September 20, 2019
Phase: N/A
Study type: Interventional

Strategies to improve uptake of cardiovascular disease preventive therapies among people living with HIV (PLHIV) are urgently needed. This study tests an innovative prevention nurse intervention to extend the HIV/AIDS treatment cascade for the treatment of hypertension and hyperlipidemia among PLHIV on suppressive antiretroviral therapy. This intervention may be scalable as an extension of ongoing HIV/AIDS treatment cascade initiatives in HIV specialty clinics nationwide.

NCT ID: NCT03643094 Completed - Hyperglycemia Clinical Trials

Golden Black Seed: Support of Metabolic Health and General Wellness.

Start date: March 14, 2018
Phase: N/A
Study type: Interventional

To document effects of consuming Golden Black Seed (brand: New Chapter Inc.) on metabolic health and wellness in human subjects. Golden Black Seed contains extracts from the turmeric root (Curcuma longa) and black cumin seeds (Nigella sativa). Both botanicals have been used traditionally in Asian cooking, and also in herbal medicine for reducing inflammation.

NCT ID: NCT03639480 Enrolling by invitation - Hypertension Clinical Trials

Study to Evaluate the Safety and Efficacy of CJ-30061 in Hypertensive Patients With Hyperlipidemia

Start date: October 13, 2017
Phase: Phase 3
Study type: Interventional

To evaluate the safety and efficacy of CJ-30061 compared with amlodipine/valsartan combination therapy and valsartan/atorvastatin combination therapy in hypertensive patients with hyperlipidemia

NCT ID: NCT03632668 Completed - Hypertension Clinical Trials

Evaluating the Pharmacokinetic Interaction Between AD-2071 and AD-2072

Start date: September 28, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the Pharmacokinetic Interaction Between AD-2071 and AD-2072 in healthy male volunteers.

NCT ID: NCT03607383 Recruiting - Dyslipidemias Clinical Trials

Red Rice Yeast in Low-density Lipoprotein (LDL) Lowering: an Efficacy Study

Start date: February 7, 2018
Phase: Phase 2
Study type: Interventional

Red yeast rice is a source of active compounds in reducing LDL levels with practically no side effects. Molval Fort is a natural product available in the Lebanese market with a combination of red yeast rice extracts, EPA/DHA and coenzyme Q10. The investigators are conducting this study to explore the effect of red yest rice extracts based product on LDL and its side effects in a sample of primary care Lebanese patients.

NCT ID: NCT03592355 Terminated - Stroke Clinical Trials

Virtual Visits at Brigham and Women's Hospital

Start date: April 13, 2018
Phase: N/A
Study type: Interventional

Clinicians slated for virtual visit rollout will be randomized (stratified by department) to either receive immediate virtual visit on-boarding (intervention arm) or delayed (3-months later) virtual visit on-boarding (control arm). The investigators plan to enroll no more than 200 clinicians. Any clinician in a department selected by the Brigham Health Virtual Care team for access to virtual visits is eligible, unless s/he saw less than 20 patients monthly over the last 6 months. The Brigham Health Virtual Care team will onboard all clinicians and provide virtual visit support as per their usual protocol. The primary study endpoint is third-available appointment, a well-adopted measure of access. Other secondary endpoints revolve around continuity, efficiency, utilization, safety, cost, and patient experience.

NCT ID: NCT03586037 Completed - Hypertension Clinical Trials

Evaluating the Pharmacokinetic Interaction Between AD-2011 and AD-2012

Start date: June 12, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the Pharmacokinetic Interaction Between AD-2011 and AD-2012 in healthy male volunteers.

NCT ID: NCT03571802 Recruiting - Obesity Clinical Trials

Pharmacokinetics of Simvastatin Post Laparoscopic Sleeve Gastrectomy (LSG)

Start date: June 13, 2018
Phase: Phase 4
Study type: Interventional

This study aims to investigate the change in systemic exposure of simvastatin post LSG.

NCT ID: NCT03566316 Completed - Clinical trials for Hypertension With Hyperlipidemia

Efficacy/Safety of Telmisartan/Amlodipine/Rosuvastatin in Hypertensive Patients With Hyperlipidemia

Start date: November 24, 2015
Phase: Phase 3
Study type: Interventional

A Randomized, Double-blind, Multi-center Phase III Clinical Trial to Evaluate the Efficacy and Safety of Telmisartan/Amlodipine and Rosuvastatin Co-administration in Hypertensive Patients with Hyperlipidemia

NCT ID: NCT03559309 Terminated - Clinical trials for Cardiovascular Diseases

Investigating the Effects of Lipid-therapy Intensification With Alirocumab on Endothelial Function, Carotid Arteries, Lipoprotein Particle Subfractions, Inflammation and Post-prandial Lipemia

ALIROCKS
Start date: June 20, 2018
Phase: Phase 4
Study type: Interventional

A prospective, open-label, pilot study with 24 cardiovascular high risk patients (N=24) having insufficient Low density lipoprotein cholesterin (LDL-C) reduction despite standard of care lipid-modifying therapies (LMTs), to evaluate the effects of potent lipid-therapy intensification via the recently approved monoclonal, human anti-PCSK9 antibody Alirocumab on endothelial function, inflammation, lipoprotein particle subfractions, carotid arteries and post-prandial lipemia in clinical routine at the Medical University of Graz.