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Heart Diseases clinical trials

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NCT ID: NCT04705779 Active, not recruiting - Obesity Clinical Trials

The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women

Start date: May 20, 2021
Phase: N/A
Study type: Interventional

This study will test whether a culturally-tailored nutrition and exercise intervention designed for African-American women will lead to sustained improvements in exercise and healthy eating through improvements in self-management mediators: mindfulness, stress management, positive reappraisal, self-regulation, and self-efficacy.

NCT ID: NCT04704349 Completed - Dementia Clinical Trials

Latest Imaging SPECT System Evaluation Phase 1

LISSE1
Start date: October 5, 2020
Phase: N/A
Study type: Interventional

Monocentric study for the evaluation of a whole body CZT scintigraphy system.

NCT ID: NCT04703439 Completed - Clinical trials for Coronary Heart Disease

An mHealth Intervention to Improve Medication Adherence and Health Outcomes

Start date: May 20, 2018
Phase: N/A
Study type: Interventional

Investigators evaluated the efficacy of a pilot-tested mHealth intervention to improving medication adherence and health outcomes among patients with coronary heart disease.

NCT ID: NCT04702373 Recruiting - Clinical trials for Congenital Heart Disease

Training in Exercise Activities and Motion for Growth (TEAM 4 Growth) RCT

T4G RCT
Start date: February 23, 2021
Phase: Phase 3
Study type: Interventional

This is a Phase III randomized controlled trial of a passive ROM exercise program that will be performed in infants with HLHS and other single right ventricle anomalies following the Norwood procedure at PHN and Auxiliary Centers.

NCT ID: NCT04700397 Recruiting - Clinical trials for Ischemic Heart Disease

A Validation Study of Nitroglycerin Induced Acute Drop of Pd/Pa (NTG-Pd/Pa) in Clinical Practice

Start date: January 2, 2021
Phase:
Study type: Observational [Patient Registry]

Hyperemia with adenosine was an elemental process in FFR examination. Adenosine injection will induce some discomfort, and increase cost expenditure. Nitroglycerine will induce an acute drop of Pd/Pa, and this lowest Pd/Pa was determined as NTG-Pd/Pa. NTG-Pd/Pa has a linear relationship with FFR value and has a good diagnostic accuracy to predict FFR≤0.80 in our recent study. There is only one prospective study report on the relationship between NTG-Pd/Pa and FFR. In this study, we aim to evaluate the safety of NTG-Pd/Pa, the repeatability and dose-response of this novel index. Furthermore, we will investigate the diagnostic accuracy of NTG-Pd/Pa, with FFR≤0.8 and Resting full-cycle ratio≤0.89 as ischemic threshold respectively.

NCT ID: NCT04699422 Completed - Surgery Clinical Trials

Serratus Anterior Plane Block Versus Standard of Care After Totally Endoscopic Aortic Valve Replacement

Start date: December 3, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to assess and compare the efficacy of a serratus anterior plane (SAP) block and our current pain protocol (Patient Controlled Intravenous Analgesia with opioids) in the prevention and treatment of acute postoperative pain after totally endoscopic aortic valve replacement (AVR) surgery.

NCT ID: NCT04699136 Completed - Cardiac Disease Clinical Trials

Cardiovascular Rehabilitation and Reeducation (CVRR) in Patients With Cardiac Pathologies and the 6-minute Stepper Test

STEPPER
Start date: January 13, 2021
Phase: N/A
Study type: Interventional

The objective is to study the validity of the 6-minute stepper test (ST6) in order to determine tolerance to effort in cardiovascular patients

NCT ID: NCT04682977 Completed - Clinical trials for Uncontrolled Diabetes (HBA1c = 10)

Piloting the IPROACTIF Program to Preserve Functioning and Prevent Cognitive Decline

Start date: April 22, 2021
Phase: N/A
Study type: Interventional

Conduct a pilot randomized control to assess the preliminary efficacy of IPROACTIF, an occupational therapist-delivered primary care intervention for aging and chronic disease management.

NCT ID: NCT04682769 Recruiting - Depression Clinical Trials

Cardiac Markers in Depressed Patients With Coronary Heart Disease - R01HL147862

TREND-3
Start date: December 1, 2020
Phase:
Study type: Observational

Depression doubles the risk of death in patients with coronary heart disease (CHD), but so far, there is insufficient evidence that we can reduce the risk of death by treating depression. This study will investigate the cardiac risk markers that are associated with depression symptoms that remain despite treatment, and identify potential targets for their treatment. The results of the study will inform the development of more effective interventions to improve both depression and survival in patients with CHD.

NCT ID: NCT04680338 Enrolling by invitation - Clinical trials for Cardiovascular Diseases

Early Detection of Silent Myocardial Ischemia

EarlySynergy
Start date: May 27, 2019
Phase: N/A
Study type: Interventional

Early-Synergy investigates a diagnostic imaging approach in asymptomatic individuals from the general population for early detection of silent myocardial ischemia and cardiac dysfunction. The diagnostic imaging approach consists of cardiac computed tomography for coronary artery calcium scoring (CT-CAC) and cardiac magnetic resonance (CMR) stress perfusion imaging. Early-Synergy investigates the effect of early detection of silent myocardial ischemia and cardiac dysfunction by CMR in asymptomatic individuals with increased CAC. In addition, the diagnostic yield of CMR for early detection of silent myocardial ischemia and cardiac dysfunction is investigated. Asymptomatic individuals at increased risk (CAC ≥ 300) are therefore randomized 1:1 to either CMR stress perfusion imaging or a control group.