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Fatigue clinical trials

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NCT ID: NCT05112380 Completed - Fatigue Clinical Trials

Fatigue Test With an XCo

Start date: November 22, 2021
Phase:
Study type: Observational

The reliability of the Xco endurance test will be assessed in sedentary adults and in overhead athletes. The experimentation will be divided into two sessions. During the sessions, the impact of the test on rotators strength and throwing performance will be explored.

NCT ID: NCT05107947 Suspended - Inflammation Clinical Trials

Light in Frail Elderly - the Effect of a Dynamic Light for Sleep and Circadian Rhythm

LIFE
Start date: October 31, 2022
Phase: N/A
Study type: Interventional

The aim of this project is to evaluate the effect of a dynamic light in order to improve the circadian rhythm, provide a better sleep and well-being, and in the long run an improved recovery. The primary question is whether dynamic artificial light with circadian stimulus can affect the circadian rhythm. The secondary question is whether this also provides better sleep and well-being. The group that is particularly interesting to study is a geriatric population that is more sensitive to circadian rhythm disorders, sleep disorders and confusion in connection with hospitalization and that can be of particular benefit from this intervention.

NCT ID: NCT05107791 Withdrawn - Clinical trials for Accommodation Disorder

Effects of Stulln and Accommodative Training

Start date: March 15, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

The present study tests the hypothesis that Stulln eyedrops improve accommodative functions by improving the short term facility of ciliary muscles that can be transferred into long-term adaptation. To test this, the investigators propose to conduct a prospective randomized control trials where participants with accommodative dysfunctions are randomly assigned to four groups: control, Stulln only and Stulln plus vision training. The investigators' theory predicts that the efficacy of Stulln will be augmented by vision training.

NCT ID: NCT05100667 Recruiting - Hypoxia Clinical Trials

A Potential Role for Oxygen in the Development of Mental Fatigue and the Subsequent Decline in Cognitive Performance

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Introduction Both Mental Fatigue (MF) and hypoxia impair multiple aspects of cognitive functioning. The decline in cognitive functioning in hypoxic conditions is associated with alterations in brain oxygenation and hemodynamic responses. These hemodynamic responses are preferably measured at the prefrontal cortex, an area of the brain that is known for its executive function and role in decision making, planning, attention and (short-term) memory. This study will investigate the role of prefrontal cortex oxygenation during the development of mental fatigue and during cognitive performances by altering the ambient oxygen availability through normobaric hypoxia (3800m; 12,9% O2) and normoxia. Methods Subjects will perform four trials in a sound-insulated climate chamber (20°C and 40% RH). Upon entry in the climatic chamber participants will adapt to the environment for 30 minutes. Next, they will perform a modified cognitive test battery "cognition", a fine motor task "Motor Performance Series" and a visuomotor-fitlight task before and after a 60-minute individualized Stroop task or control task (randomized. blinded, placebo controlled, counter-balanced, cross-over design). Nearinfrared spectroscopy (NIRS) will be used to assess hemodynamic changes (oxygenated hemoglobin (O2Hb), deoxygenated-hemoglobin (HHb) and total hemoglobin (tHb)) at the PFC. Hypotheses 1) MF will lead to earlier changes in the prefrontal NIRS-parameters (O2Hb, HHb, tHb) with lower oxygen availability. 2) The effects of MF on cognitive performance manifest itself to a greater extent with lower oxygen availability.3) Visuomotor performance declines to a greater extent due to MF with lower oxygen availability.

NCT ID: NCT05096130 Withdrawn - Fatigue Clinical Trials

Lifestyle Medicine Strategies for Combating Sleepiness and Fatigue in Professional Drivers

HighWay2Health
Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Sleep has a number of health benefits, including memory and learning, vitality and energy as well as high quality of life levels. Lack of sleep impairs judgment, impacts longevity and safety, and increases the risk of a number of diseases including obesity, hypertension, heart disease, diabetes, mood disorders, and impaired immune function. In addition lack of sleep or disturbance of normal sleep cycle could have a major impact on people's lives and working performance such as driving. Daily sleepiness is a problem concerning professions with a non-fixed schedule. Specifically, professional long-haul drivers confront sleepiness problems and in combination with fatigue, they are prone to driving accidents and other incidents. Sleep quality and quantity are closed related to fatigue which is one of the most common reasons for driving and working accidents. In recent years, car accidents involving professional drives have increased significantly. The main reasons for those accidents were fatigue and sleepiness due to long hours of driving or difficult working conditions according to the recent European report (Driver Fatigue in European Road Transport - etf-europe.org). Lifestyle Medicine addresses health risk factors in primary, secondary, and tertiary prevention of developing disease rather than on acute care and reacting to illness, injury, and disease. Lifestyle Medicine strategies targeting modifiable risk factors, such as diet, sleep, stress, and physical activity. By applying those regimes the investigators could improve physical and mental health levels that can affect the quality of sleep, reducing daily sleepiness and fatigue, in professional drivers operating coaches and trucks. Any intervention that could improve alertness and reduce fatigue and sleepiness in those people, will automatically improve safety, reduce driving accidents and save lives and resources.

NCT ID: NCT05094310 Recruiting - Breast Cancer Clinical Trials

Genetic Predictors of Response to Acupuncture for Cancer-related Fatigue Among Breast Cancer Patients After Chemotherapy

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Genetic predictors of response to acupuncture for cancer-related fatigue among breast cancer patients after chemotherapy.

NCT ID: NCT05094297 Recruiting - Depression Clinical Trials

Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

This research study is being done to investigate if the GH Method exercise program positively affects body composition, improves physical abilities and can improve the overall sense of wellbeing (e.g. depression, PTSD, etc.) in U.S. Veterans. Subjects will be asked to complete 94 total visits (four (4) study testing visits and 90 exercise visits). Enrolled subjects will be tested for fitness, strength, and health risk factors at UIC 4 times and will complete 90 exercise training visits at the GH FITLab over the next 18 months. Subjects will also be asked to complete questionnaires about depression, post-traumatic stress symptoms and thoughts about harming oneself.

NCT ID: NCT05077046 Completed - Muscle Fatigue Clinical Trials

Efficacy of an Ergonomic Handwriting Pen - The AWP Pen Study

Start date: September 27, 2021
Phase: N/A
Study type: Interventional

This clinical investigation is a monocenter, prospective, randomized, controlled, counter-balanced, two-arm study investigating the effect of a novel ergonomic handwriting pen.

NCT ID: NCT05075694 Completed - Fatigue Clinical Trials

Cukurova University Faculty of Medicine Non-interventional Clinical Research Institutional Ethics Committe

Start date: December 15, 2021
Phase: N/A
Study type: Interventional

This research was carried out to determine the effect of therapeutic touch on sleep quality and fatigue in menopausal women.

NCT ID: NCT05073848 Recruiting - Cancer Remission Clinical Trials

Relationships Between Physical Activity and Different Measures of Fatigue in Cancer Survivors

Start date: October 20, 2021
Phase:
Study type: Observational

This is an investigation of possible relationships between daily physical activity (PA) and different measurements of fatigue in cancer survivors participating in a cancer exercise program.