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Fatigue clinical trials

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NCT ID: NCT05089071 Recruiting - Fatigue Clinical Trials

Effect of Colonoscopy AI System for Colon Polyp Detection According to the Workload of Endoscopy Units

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

Computer-aided detection (CADe) systems have been actively researched for polyp detection in colonoscopy. We aim to identify the effect of CADe system according to the workload of endoscopy units

NCT ID: NCT05077046 Recruiting - Muscle Fatigue Clinical Trials

Efficacy of an Ergonomic Handwriting Pen - The AWP Pen Study

Start date: September 27, 2021
Phase: N/A
Study type: Interventional

This clinical investigation is a monocenter, prospective, randomized, controlled, counter-balanced, two-arm study investigating the effect of a novel ergonomic handwriting pen.

NCT ID: NCT05075694 Not yet recruiting - Fatigue Clinical Trials

Cukurova University Faculty of Medicine Non-interventional Clinical Research Institutional Ethics Committe

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

This study will be conducted as a single-blind randomized placebo-controlled experimental study to determine the effect of therapeutic touch sleep quality and fatigue in women in the menopausal period. The research is planned to be carried out between 15 November 2021 and 15 March 2022 in the Bornova gynecology oncology polyclinic of the İzmir Health Sciences University Tepecik Training and Research Hospital affiliated to the Ministry of Health. The population of the research consists of women application in the Gynecology Oncology Polyclinic of the İzmir Health Sciences University Tepecik Training and Research Hospital affiliated to the Ministry of Health. The number of samples was calculated in G*power 3.1.9.6 program. Accordingly, 21 women were calculated for each group, with effect size (d=1.37), 5% margin of error (α=0.05), and 99 % power (1-β=0.99). However, considering the possible losses, the number of samples was increased by 15 % and the study was planned to be conducted with 48 women, 24 in the intervention group and 24 in the placebo group. Data will be collected through the Personal Information Form, the Piper Fatigue Scale (PFS) and the Pittsburg Sleep Quality Index (PSQI). Data analysis will be performed using the IBM SPSS Statistics 24.0 program. Statistical significance will be taken 0.05. Therapeutic touch is thought to be one of the applications that can be used in improving women's health, as it is a non-drug application that is easy to apply, has no side effects and can be applied independently by midwives/nurses.

NCT ID: NCT05073848 Not yet recruiting - Cancer Remission Clinical Trials

Relationships Between Physical Activity and Different Measures of Fatigue in Cancer Survivors

Start date: December 1, 2021
Phase:
Study type: Observational

This is an investigation of possible relationships between daily physical activity (PA) and different measurements of fatigue in cancer survivors participating in a cancer exercise program.

NCT ID: NCT05067777 Not yet recruiting - Prostate Carcinoma Clinical Trials

Massage for Prostate Cancer-Related Fatigue, mPROSTATE Study

mPROSTATE
Start date: October 30, 2021
Phase: Phase 2
Study type: Interventional

This phase II trial investigates the effect of massage in decreasing prostate cancer-related fatigue. Massage therapy has well known health benefits. This trial aims to find out if massage and touch therapies reduce fatigue due to cancer, and to learn if these therapies are better than traditional medicine or psychology for cancer related fatigue.

NCT ID: NCT05061056 Not yet recruiting - Fatigue Clinical Trials

Effects of Neuromuscular Electrical Stimulation Parameters on Torque, Fatigue, and Oxygen Extraction

NMES
Start date: November 2, 2021
Phase: N/A
Study type: Interventional

Neuromuscular Electrical Stimulation (NMES) can minimize muscle atrophy, complications related to muscle disuse and improved neuromuscular performance. However, it is still unclear the influence of specific physical parameters, including carrier frequency, burst duration, and duty cycle regarding the greater generation of evoked torque, sensory discomfort, muscle fatigue, and peripheral oxygen extraction. Thus, the aim of this study is to compare the effects of different NMES protocols applied to the triceps surae muscle for evoked torque, muscle fatigue, sensory discomfort, and peripheral oxygen extraction in healthy individuals. This is a crossover, experimental, randomized, double-blind trial composed of apparently healthy participants. All NMES protocols will be tested on the same individual with randomization of the sequence of intervention protocols. There will be a total of 6 encounters with seven days between them. Session 1 will evaluate the anthropometric measures, the maximum intensity for each intervention protocol, and the sequence of intervention protocols for each individual will be randomized. Sessions 2, 3, 4, and 5 will be composed equally with the assessment of the maximum voluntary and evoked joint torque of the triceps surae muscle through the isokinetic dynamometer, evaluation of muscle fatigue through the H-reflex, M-wave, fatigue index, time-torque-integral, and recruitment curve, evaluation of peripheral oxygen extraction through NIRS (Near Infrared Spectroscopy), electromyographic signals to assessed the RMS (root mean square) and the median frequency, evaluation of the level of sensory discomfort through the Visual Analog Pain Scale and finally by the NMES protocol. The 6th session will be the replication of the 2nd session of each individual. The EENM protocols will be as follows: CR10% (Russian Current with 2500 Hz, modulated in bursts of 50 Hz, 200 µs and 10% duty cycle - 2 ms bursts and 18 ms interbusrts), CR20% (Russian Current with 2500 Hz, modulated in bursts of 50 Hz, 200 µs and 20% of duty cycle - 4 ms bursts and 16 ms interbusrts), CA10% (Aussie current with 1000 Hz, modulated in bursts of 50 Hz, 500 µs and 10% duty cycle - 2 ms of bursts and 18 ms interbusrts), CA20% (Aussie current with 1000 Hz, modulated in bursts of 50 Hz, 500 µs and 20% of duty cycle - 4 ms of bursts and 16 ms interbusrts) all protocols will be performed on the triceps surae muscle.

NCT ID: NCT05047952 Recruiting - Fatigue Clinical Trials

Vortioxetine for Post-Covid-19 Syndrome

Start date: September 16, 2021
Phase: Phase 2
Study type: Interventional

A randomized, double-blinded, placebo-controlled trial will be conducted to evaluate vortioxetine, an antidepressant with established pro-cognitive properties, for the treatment of cognitive deficits which develop during or after an infection consistent with COVID-19, continue for more than 12 weeks and are not explained by an alternative diagnosis (i.e., post-COVID-19 syndrome). Participants will receive vortioxetine (10-20 mg) or placebo for 8 weeks. Changes in cognitive functioning from baseline to endpoint (week 8) will be assessed via the Digit Symbol Substitution Test (DSST).

NCT ID: NCT05043038 Enrolling by invitation - Fatigue Clinical Trials

Effect of Night Float Call on Sleep and Activity Patterns Among Anesthesia Residents

Start date: August 1, 2019
Phase:
Study type: Observational

With increasing awareness about physician fatigue and its effect on patient safety, residency programs are increasingly transitioning to a night float call system. In other industries, multiple night shifts in a row can cause a disruption in the circadian rhythm, sleep debt, shift work disorder, that is related to chronic medical conditions such as obesity and cardiovascular disease. We will evaluate the effect of different call structures on resident activity, sleep and self reported measures of wellness using a commercially available Fitbit device.

NCT ID: NCT05041946 Active, not recruiting - Cancer Clinical Trials

Patient Controlled Methylphenidate for Cancer Related Fatigue: A Double Blind, Randomized, Placebo Controlled Trial

Start date: July 16, 2003
Phase: Phase 3
Study type: Interventional

To determine the effectiveness of patient controlled methylphenidate as compared to placebo for the management of cancer related fatigue as determined by the Functional Assessment of Chronic Illness Therapy (FACIT)-F Fatigue score.

NCT ID: NCT05037071 Recruiting - Clinical trials for Muscle; Fatigue, Heart

Arm Compression on Muscle Oxygen Saturation

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

This study is designed to observe muscle oxygen saturation during intense video game using gridlock training with and without upper arm compression sleeves.