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Fatigue clinical trials

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NCT ID: NCT00884338 Recruiting - Fatigue Clinical Trials

Cognitive Function After Stem Cell Transplantation

Start date: May 2009
Phase: Phase 3
Study type: Interventional

The trial will evaluate the effects of an exercise program on the physical and cognitive performance of patients with hematological neoplastic diseases after high dose chemotherapy with stem cell support.

NCT ID: NCT00883714 Recruiting - Fatigue Clinical Trials

Exercise During the Allogeneic Stem Cell Transplantation

Start date: May 2009
Phase: Phase 3
Study type: Interventional

The study will evaluate the effects of a structured endurance exercise program on the physical performance, the mood and the complications of patients with hematological malignancies undergoing a high-dose chemotherapy followed by an allogeneic peripheral blood stem cell transplantation.

NCT ID: NCT00874510 Completed - Fatigue Clinical Trials

A Randomized Controlled Trial of Mandatory Naps for Physicians in Training

Start date: June 2009
Phase: Phase 3
Study type: Interventional

This study will consist of a randomized controlled trial in which the investigators test the feasibility and effectiveness of mandatory nap programs for physicians in training. One site will be the general medical service of the Philadelphia Veterans Affairs Medical Center. The other will be the oncology service of the Hospital of the University of Pennsylvania. The primary outcome will be the amount slept while on call. The first year will test the efficacy of a 5 hour mandatory nap schedule, the second year will test the efficacy of a 3 hour mandatory nap schedule.

NCT ID: NCT00866970 Completed - Fatigue Clinical Trials

Safety, Efficacy and Pharmacokinetics of ALD518 in Patients With Non-Small Cell Lung Cancer-related Fatigue and Cachexia

Start date: September 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to asses the safety and efficacy of ALD518 in patients with Non-Small Cell Lung Cancer-Related Fatigue and cachexia (weight-loss).

NCT ID: NCT00862186 Completed - Neoplasms Clinical Trials

Self-Management of Cancer-Related Fatigue by Adolescents

Start date: April 2009
Phase: N/A
Study type: Interventional

This study will investigate self-management of cancer-related fatigue by adolescents through pilot study of an evidence based educational resource.

NCT ID: NCT00860236 Completed - Clinical trials for Chronic Fatigue Syndrome

Giardia Induced Fatigue and Functional Gastrointestinal Diseases

GIFF
Start date: March 2009
Phase: Phase 4
Study type: Interventional

A giardiasis outbreak in Bergen has given us the opportunity to approach two basic research questions of national and global importance: - Studying the pathoimmunology of giardiasis in a natural setting, and following the genetic and immunological responses leading to recovery or persistent disease and sequelae. - Studying the two disease entities FGID and CFS when induced by acute giardiasi and their risk factors. - Interventional cognitive behavioural therapy is the only intervention documented to have significant effect on CFS outcome, and conventional cognitive behavioural therapy will be compared to a psycho-educational programme in the format of a randomised controlled trial.

NCT ID: NCT00856453 Terminated - Depression Clinical Trials

Yoga in Relieving Fatigue in Patients Undergoing Chemotherapy for Ovarian Cancer

Start date: May 2009
Phase: N/A
Study type: Interventional

RATIONALE: Yoga may decrease fatigue, distress, and depression, and improve sleep quality in patients undergoing chemotherapy for ovarian cancer. It is not yet known whether practicing yoga in group classes is more effective than practicing yoga at home. PURPOSE: This randomized clinical trial is studying how well yoga works in relieving fatigue in patients undergoing chemotherapy for ovarian cancer.

NCT ID: NCT00852111 Completed - Cancer Clinical Trials

Molecular-Genetic Correlates of Fatigue in Cancer Patients Receiving Localized External Beam Radiation Therapy

Start date: April 23, 2009
Phase:
Study type: Observational

Background: - Researchers have studied the causes of fatigue during treatments for various diseases, but these results have not been conclusive. - More information on the physical changes that affect the body during treatment may help identify biological or chemical factors that contribute to patient fatigue, which may allow physicians to identify individuals who may be more at risk of feeling fatigue before, during, and after treatment for diseases such as cancer. Objectives: - To identify factors contributing to fatigue in men who are undergoing radiation treatment for prostate cancer. Eligibility: - Men 18 years of age and older who are scheduled to receive localized radiation treatment for prostate cancer. Design: - Six outpatient visits to the NIH Clinical Center, approximately on the same day and same time of day: - First visit before beginning radiation treatment. - Once a week for the first 2 weeks of the treatment, once at the midpoint of treatment, once at the end of treatment. - Final visit 4 weeks after completion of radiation treatment. - Initial visit will involve a physical examination and questions about medical history. - Evaluations during the treatment period: - Blood draws to identify cells and chemicals associated with inflammation and fatigue. - Questions about physical activity, fatigue, depression, and quality of life.

NCT ID: NCT00851812 Completed - Fatigue Clinical Trials

Exercise for Breast Cancer Patients (EXCAP)

Start date: May 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to examine if exercise helps improve cancer-related fatigue. Hypothesis: A structured home-based walking and progressive resistance exercise program will be efficacious in relieving cancer-related fatigue, preventing aerobic and anaerobic deconditioning and skeletal muscle wasting, as well as improving inflammatory cytokine profiles in breast cancer survivors as well as those receiving radiation treatment.

NCT ID: NCT00848692 Completed - Clinical trials for Chronic Fatigue Syndrome

Drug Intervention in Chronic Fatigue Syndrome

KTS-1-2008
Start date: June 2008
Phase: Phase 2/Phase 3
Study type: Interventional

Based on pilot patient observations,the investigators anticipate that chronic fatigue syndrome (CFS) patients may benefit from B-cell depletion therapy. The hypothesis is that at least a subset of CFS patients have an activated immune system involving B-lymphocytes, and that B-cell depletion may alleviate symptoms.