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NCT ID: NCT05892419 Enrolling by invitation - Memory Clinical Trials

Electrophysiological Signatures of Distinct Working Memory Subprocesses That Predict Long-term Memory Success

WMLTM
Start date: July 1, 2022
Phase:
Study type: Observational

Healthy young adults will view pictures of items while the investigators record electroencephalogram (EEG) brain activity. Then, the investigators will ask the participants to report which items the participants remember seeing. The investigators will examine how the measured brain activity relates to which pictures the participants remember.

NCT ID: NCT05890274 Enrolling by invitation - Atrial Fibrillation Clinical Trials

Atrial Fibrillation (AF) and Electrocardiogram (EKG) Interpretation Project ECHO

Start date: September 4, 2022
Phase: N/A
Study type: Interventional

The goal of this study is to determine the effectiveness of a direct-to-provider virtual education program ("AF and EKG Interpretation Project ECHO") for primary care providers who manage patients with atrial fibrillation (AF). The main questions this study aims to answer are: 1. Will participants have improvement in knowledge and confidence in managing patients with atrial fibrillation after program completion? 2. Will quality and performance metrics improve at the patient level for program participants? Participants will be asked to: - Participate in 12 hours of virtual education sessions over twelve weeks via Zoom. - Complete a knowledge and confidence assessment online before the program starts and after its completion.

NCT ID: NCT05890196 Enrolling by invitation - Breast Cancer Clinical Trials

Autologous Fat Grafting in Radiated Soft Tissue Reconstruction

Start date: March 1, 2023
Phase:
Study type: Observational

The purpose of this study is to observe the effect of autologous fat grafting on soft tissue reconstruction of the breast following radiation treatment. Moving fat from one part of the body to another has been used for reconstruction for hundreds of years. However, it is not fully understood how well this works in reconstruction after radiation is used for cancer treatment.

NCT ID: NCT05890001 Enrolling by invitation - Erosive Esophagitis Clinical Trials

A Study to Evaluate the Long-Term Safety of BLI5100 in Patients With Gastroesophageal Reflux Disease

Start date: April 5, 2023
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the safety of up to 12 months (52 weeks) of once daily oral administration of BLI5100 in patients with non-erosive reflux disease (NERD) or healed erosive esophagitis (EE).

NCT ID: NCT05889806 Enrolling by invitation - Clinical trials for Cardiovascular Diseases

AUD Biomarkers Study (Proteomic and Genomic Analysis of Biospecimens)

Start date: May 10, 2023
Phase:
Study type: Observational

Study purpose: to explore the entire spectrum of proteomic and genomic changes (amongst others) involved in diseases and in healthy/control populations. The Study is designed to discover biomarkers, develop and validate diagnostic assays, instruments and therapeutics as well as other medical research. Specifically, researchers may analyze proteins, RNA, DNA copy number changes, including large and small (1,000-100,000 kb) scale rearrangements, transcription profiles, epigenetic modifications, sequence variation, and sequence in both diseased tissue and case-matched germline DNA from Subjects.

NCT ID: NCT05889273 Enrolling by invitation - Clinical trials for Autism Spectrum Disorder

ML-004 Open-Label Extension Study in Adults and Adolescents With Autism Spectrum Disorders (ASD)

Start date: June 1, 2023
Phase: Phase 2
Study type: Interventional

ML-004-003 is a multi-center, open-label extension study that will enroll approximately 120 adolescent and adult subjects with ASD that have completed study ML-004-002. The primary objective of the study will be to evaluate the safety of ML-004 in subjects with ASD.

NCT ID: NCT05888623 Enrolling by invitation - Clinical trials for Colorectal Neoplasms

Computer Assisted Detection of Neoplasia During Colonoscopy Evaluation

CADeNCE
Start date: October 1, 2022
Phase:
Study type: Observational

The purpose of this study is to evaluate the effect of artificial intelligence systems used during colonoscopy on the detection of precancerous polyps in the colon.

NCT ID: NCT05887934 Enrolling by invitation - Lead Exposure Clinical Trials

Bone-Lead Level Associations With Brain and Mental Health

Start date: August 17, 2023
Phase:
Study type: Observational

The goal of this study is to assess cumulative lead exposure among treatment-seeking patients in the MUSC hospital system receiving experimental transcranial magnetic stimulation (TMS), transcranial direct-current stimulation (tDCS), an electroencephalogram (EEG), and/or transcutaneous auricular vagus nerve stimulation (taVNS) therapies to determine whether lead exposure represents a risk factor for more severe mental illness or a modifier of treatment response. Information will be obtained from patients with a variety of neuropsychiatric disorders recruited to existing hospital studies. This information will include the results of bone-lead testing, brief cognitive tests, and self-reported psychiatric symptoms and behaviors.

NCT ID: NCT05887375 Enrolling by invitation - Spine Surgery Clinical Trials

Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine Surgery

Start date: August 3, 2023
Phase: Phase 4
Study type: Interventional

This is an active-comparator controlled study to evaluate the effect of sugammadex compared to neostigmine/glycopyrrolate for reversal of rocuronium on the incidence of urinary retention after subjects undergo elective ambulatory spine surgery.

NCT ID: NCT05886270 Enrolling by invitation - Home Injury Clinical Trials

Implementation of the Child Housing Assessment for a Safe Environment

CHASE
Start date: June 24, 2022
Phase: N/A
Study type: Interventional

This implementation study uses a multi-method quantitative and qualitative, non-experimental design to estimate the magnitude of home injury risks, identify strategies for addressing those risks and sustaining those interventions, and to calculate the costs of housing-related modifications to prevent childhood home injuries. The study objectives are to: Aim 1. Implement injury prevention measures based on safety hazards identified using the CHASE Tool within 300 low-income households (at or below 80% AMI) in Baltimore City or County; Aim 2. Determine the costs of the injury prevention measures completed by residents and/or professional providers; Aim 3. Conduct a formative evaluation using mixed methods to 3a. determine feasibility of incorporating injury prevention into residential programs from the perspective of installers and residents, including identifying barriers and facilitators, and 3b. understand the consistency of implementing and maintaining the injury prevention measures across referral sources, by residents and staff.