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NCT ID: NCT05206994 Enrolling by invitation - Adolescent Behavior Clinical Trials

Evaluation of the Close to Home Program in California

Start date: October 4, 2021
Phase: N/A
Study type: Interventional

Investigators propose to rigorously evaluate the Close to Home (C2H) model via a cluster-matched control trial across 18 diverse communities (9 C2H, 9 control) in California via collection and analyses of social network, school-based and social media data. Close to Home is a primary prevention community mobilization model implemented in 10 communities across California that engages community members across multiple sectors and social networks to strengthen community connections and shift social norms regarding sexual violence (SV), but has never been rigorously evaluated. C2H moves beyond criminal justice, lobbying, or school-based curricular approaches, taking a true community-level and community-led approach. This is a five-year project, funded by the Centers for Disease Control and Prevention (CDC) for 3 years with competitive awards for years 4 and 5, and is conducted in partnership with the California Department of Public Health (CDPH) and ValorUs (formerly CALCASA). The University of California, San Diego (UCSD) and CDPH partnership is uniquely poised to conduct the first rigorous evaluation of C2H in California at this time.

NCT ID: NCT05206981 Recruiting - Traumatic Fracture Clinical Trials

Device Global Registry for the IlluminOss Bone Stabilization System

Start date: June 11, 2021
Phase:
Study type: Observational [Patient Registry]

This is a multi-center, observational patient registry. The primary objective of the study is to collect safety and performance data on the IlluminOss Device when used to provide stabilization and alignment for the treatment of traumatic or impending and pathologic fractures.

NCT ID: NCT05206955 Recruiting - Fontan Palliation Clinical Trials

Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan Physiology

Start date: February 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to find out more about the effectiveness of Tadalafil in improving hemodynamic capabilities, endothelial function, and end-organ function in patients who have previously undergone a Fontan Palliation.

NCT ID: NCT05206942 Not yet recruiting - Clinical trials for Renal Cell Carcinoma

Serial Ultrasound to Detect Early Response to Immunotherapy in Advanced Renal Cell Carcinoma

Start date: February 2022
Phase: N/A
Study type: Interventional

Primary objective is to assess whether changes in quantitative tumor perfusion parameters 3 weeks after start of treatment of renal cell carcinoma (RCC) patients with immune checkpoint inhibitor (ICI) therapy. Secondary objectives are to evaluate if there is an optimal ultrasound imaging modality (conventional power Doppler or LEAD ultrasound or CEUS) or optimal time point to predict initial objective response

NCT ID: NCT05206929 Not yet recruiting - Heart Failure Clinical Trials

Cardiac Surgery Sternal Precautions

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

Our study aims to compare postoperative outcomes, postoperative pain and postoperative quality of lives in patients who receive the standard sternal precautions to those in patients who received self-managed sternal precautions following sternotomy for cardiac surgeries. The purpose of the study is to see if self-managed sternal precautions following sternotomy for cardiac surgeries lead to better quality of lives while maintaining same postoperative pain and rate of postoperative adverse events than standard sternal precautions. Postoperative pain and postoperative quality of lives will be assessed by phone call surveys. Postoperative outcomes will be measured by following the patients for up to a year using electronic medical record.

NCT ID: NCT05206877 Not yet recruiting - Glaucoma Clinical Trials

TOPICAL INSULIN FOR GLAUCOMA, Phase 1

TING1
Start date: February 1, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this Phase 1 trial is to determine the safety over 1-2 months of topic sterile human recombinant insulin on subjects with optic neuropathies (glaucoma, ischecmic optic neuropathy, and optic disc drusen).

NCT ID: NCT05206864 Active, not recruiting - Healthy Clinical Trials

Food Trial to Evaluate the Safety and Tolerability of SBD111 in Health Adults

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The aim of the trial is to determine if the synbiotic (prebiotic and probiotic), provided twice daily (capsule) is safe and tolerable in healthy adults.

NCT ID: NCT05206630 Recruiting - Low Back Pain Clinical Trials

ED Physical Therapy for Chronic Low Back Pain

Start date: January 11, 2022
Phase: N/A
Study type: Interventional

Emergency department (ED)-initiated physical therapy is a rapidly growing resource and represents a promising treatment approach to low back pain. This clinical trial will evaluate an innovative model of an emergency department "embedded" physical therapist to treat patients with chronic low back pain, with a focus on improving patient functioning and reducing opioid use.

NCT ID: NCT05206513 Recruiting - Cerebral Palsy Clinical Trials

Study to Assess the Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Dyskinesia Due to Cerebral Palsy

Start date: January 2022
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the efficacy of valbenazine versus placebo in participants aged 6 to 70 years for the treatment of dyskinesia due to cerebral palsy (DCP).

NCT ID: NCT05206500 Not yet recruiting - Clinical trials for Urinary Tract Infections

NextGen - Clinical Implication of Next Generation Sequencing

Start date: March 2022
Phase: Phase 4
Study type: Interventional

Recently more advanced techniques, including Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) are available to detect bacteria in urine based on bacterial genomes. Comparing to traditional culture, these techniques have more sensitivity and could potentially be of a great help in patients with Colony Count of less than 10,000 and more than zero.