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NCT ID: NCT04774861 Recruiting - Clinical trials for Coronary Artery Disease

Correlation of Cardiac Computed Tomography Angiography Dimensions and Ethnicity in Trinidad

CADET
Start date: August 1, 2020
Phase:
Study type: Observational

The aim of this study is to compare coronary artery dimensions on Cardiac CT angiography amongst different ethnicities in Trinidad.

NCT ID: NCT04554901 Recruiting - Clinical trials for Platelet Dysfunction

The Effect of Cocoa on Platelet Function Profiles in Patients

ECLAIR
Start date: September 1, 2020
Phase: N/A
Study type: Interventional

The effects of chocolate on cardiovascular health are still a matter of debate. It can potentially favor cardiovascular health through the antioxidative effects of cocoa ingredients, such as polyphenols (present in dark but not white chocolate).

NCT ID: NCT04400760 Recruiting - Clinical trials for Platelet Dysfunction

The Effect of Dapagliflozin on Platelet Function testinG Profiles in Diabetic PatiEnts.

EDGE
Start date: May 1, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

Sodium GLucose Transport 2 inhibitors (SGLT2I), including dapagliflozin, reduce the likelihood of hospitalization for heart failure and death in persons with type 2 diabetes, of which the mechanism has not been fully elucidated. The mechanistic effects of dapagliflozin on platelet function profiles have not yet been ascertained. It remains unclear if this reduction in cardiovascular death is mediated by decreased platelet reactivity.

NCT ID: NCT04388540 Completed - Iodine Deficiency Clinical Trials

Caribbean Island Urinary Iodine Survey 2018

CRUISE
Start date: January 1, 2018
Phase:
Study type: Observational

Many of the Caribbean island nations have no data on iodine status in their populations. Iodine deficiency in children can reduce IQ but can be easily corrected through a program of salt iodization. The study will be located at 11 islands of the Caribbean region. At each of the 11 study sites, we will measure the iodine status in school-age children by collecting morning spot urine samples for measurement of urinary iodine concentration (UIC). We will also measure height and weight in all children. We will collect a repeat, next-day spot urine sample in 1/3rd of children to adjust for intra-individual variation in spot UIC and calculate the distribution of population intake.

NCT ID: NCT04342819 Recruiting - Clinical trials for Platelet Dysfunction Due to Drugs

The Effect of empagliFlozin on Platelet Function profilEs in diabetiC patienTs - The EFFECT Study.

EFFECT
Start date: January 1, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The mechanistic effects of empagliflozin on platelet function profiles have not yet been ascertained.

NCT ID: NCT04336137 Recruiting - Psychotic Disorders Clinical Trials

INTernational REsearch Programme on Psychosis In Diverse Settings

INTREPID II
Start date: May 1, 2018
Phase:
Study type: Observational

INTREPID II aims to investigate variability in incidence, presentation, outcome, and impact of untreated psychotic disorders in three countries - India, Nigeria, and Trinidad - through four interconnected observational studies: 1. Study 1 on Incidence, Presentation, and Risk has the objective to investigate the incidence and presentation of untreated psychotic disorders in each setting and associated risk factors. 2. Study 2 on Course and Outcome has the objective to investigate two-year course and outcome of psychotic disorders and associated factors. 3. Study 3 on Help-seeking and Impact has the objective to investigate (a) help-seeking; and (b) the impact of psychotic disorders on individuals and families, using a combination of quantitative and qualitative approaches. 4. Study 4 on Physical Health has the objective to investigate the types and prevalence of physical health problems and related biological markers.

NCT ID: NCT04233619 Recruiting - Retinal Disease Clinical Trials

Correlation of Microvascular Ophthalmic Disease With Macrovascular Coronary Artery Disease in Trinidad

EYE-MI TNT
Start date: May 1, 2019
Phase:
Study type: Observational

Coronary artery disease (CAD) is the leading cause of death in Trinidad and Tobago. Early detection and management can help improve morbidity and mortality. Retinal artery microvascular disease has been shown to directly correlate with coronary artery disease. Retinal artery calibre screening via the Optic Coherence Tomography (OCT) will provide a non-invasive method of diagnosing CAD.

NCT ID: NCT04206176 Completed - Clinical trials for Platelet Dysfunction Due to Drugs

The Effects of loW Dose tIcagrelor on Platelet Function Testing in Patients With Stable Coronary arTery Disease

TWIST
Start date: October 1, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This study aims to assess the effects of low dose ticagrelor on platelet function testing in patients with stable coronary artery disease.

NCT ID: NCT04001816 Recruiting - Clinical trials for Bimaxillary Proclination

A Randomized Clinical Trial to Investigate Whether Self Ligating Brackets or Conventional Brackets Are Better for Treating Bimaxillary Proclination

Start date: January 4, 2017
Phase: N/A
Study type: Interventional

The study is a single blind randomised control trial.The patients will be randomly assigned to have conventional brackets placed or self ligating brackets placed. All patients will undergo full Orthodontic records. This will include an Orthodontic assesment, study models relevant xrays (orthopantogram and a cephalomgram) and clinical photos. After records analysis, patients will be given a prophylaxis and oral hygiene instructions. Either 3m Victory Series™ Metal Braces or 3m SmartClip™ SL3 Self-Ligating Braces both bracket types will carry the MBT prescription 0.022 slot height, will be bonded using Transbond™ XT (3M Unitek, Monrovia, California, USA) composite resin according to the manufactuer's instruction. These patients will be recalled at monthly intervals for the duration of treatment time which will be 3 years. A cephalogram will be taken at the end of treatment

NCT ID: NCT03863262 Completed - Depression Clinical Trials

Screening for Depression in cADiovasCular pAtients at a Tertiary Center in Trinidad.

SAD-CAT
Start date: November 8, 2018
Phase:
Study type: Observational

This was an observational study aimed to screen patients with cardiovascular disease for depression in Trinidad and Tobago in a tertiary center and to determine if there is a significant association between patients with symptoms of depression and other comorbidities. Patients (N=1203) were randomly selected from the outpatient cardiology clinics at the Eric Williams Medical Sciences Complex. After fulfilling the inclusion criteria and informed consent were obtained, they were given the case report form which included the Patient Health Questionnaire 9.