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NCT ID: NCT00387686 Terminated - Fractures Clinical Trials

A Phase 2/3 Multicenter, Controlled Trial Of rhBMP-2/CPM In Tibial Fractures

Start date: November 2006
Phase: Phase 2/Phase 3
Study type: Interventional

The primary objective of this study is to assess whether a single dose of rhBMP-2/CPM administered at the fracture site via percutaneous injection, in combination with standard of care, accelerates fracture union and return to normal function in subjects who have a closed diaphyseal tibial fracture when compared to standard of care alone.

NCT ID: NCT00381095 Terminated - Cancer Clinical Trials

A Study To Evaluate Pregabalin In The Treatment Of Moderate To Severe Chronic Bone Pain Related To Metastatic Cancer

COPE
Start date: December 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the analgesic efficacy of flexibly-dosed pregabalin in the adjunctive treatment of subjects with cancer-induced bone pain.

NCT ID: NCT00366080 Terminated - Narcolepsy Clinical Trials

Effectiveness Of The Drug GSK189254 In Treating Patients With Narcolepsy

Start date: November 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the effectiveness and safety of the drug GSK189254 in treating patients with narcolepsy.

NCT ID: NCT00364533 Terminated - Arthroplasty Clinical Trials

A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) in the Treatment of Acute Pain After Hip Replacement Surgery Compared With Oxycodone and Placebo Followed by a Voluntary Open-Label Extension For Safety

Start date: October 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to test in patients who have had hip replacement surgery the effectiveness (level of pain control) and the safety of 3 different dose levels of CG5503 compared with placebo and with 10-mg oxycodone during the 72-hour double-blind period and to assess the safety of the drug for 9 days after patients completed the double blind period.

NCT ID: NCT00362765 Terminated - Type 2 Diabetes Clinical Trials

Fenofibrate and Metformin Insulin Sensitivity in Type 2 Diabetics Study

Start date: October 2006
Phase: Phase 2/Phase 3
Study type: Interventional

Double-blind, randomized placebo-controlled study in type 2 diabetes and dyslipidemic patients.Patients will be randomized to one of four treatment arms for 16 weeks: placebo, fenofibrate, metformin, or metformin and fenofibrate combination.

NCT ID: NCT00361868 Terminated - Dyslipidemia Clinical Trials

Fenofibrate and Metformin Fixed Combination vs Rosiglitazone - FAME ROSI

Start date: June 2006
Phase: Phase 3
Study type: Interventional

Under conditions of first-line drug treatment in antidiabetic drug naïve/drug free patients with type 2 diabetes mellitus and dyslipidemia, to show that :- the efficacy of a fixed combination (FC) of fenofibrate and metformin on glycemic control is not inferior to that of rosiglitazone and the efficacy of FC of fenofibrate and metformin on triglyceride control is superior to that of rosiglitazone.

NCT ID: NCT00356421 Terminated - Clinical trials for Diabetes Mellitus, Type 1

A Clinical Trial Comparing Efficacy and Safety of Exubera® and Humalog®

Start date: November 2006
Phase: Phase 4
Study type: Interventional

To compare efficacy and safety of Exubera® vs Humalog in patients with type 1 diabetes mellitus

NCT ID: NCT00348894 Terminated - Pain Clinical Trials

[S,S]-Reboxetine Long Term Safety Study In Chronic Painful Diabetic Peripheral Neuropathy.

Start date: July 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the long-term safety and tolerability of [S,S]-Reboxetine in patients with chronic painful diabetic peripheral neuropathy

NCT ID: NCT00348712 Terminated - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Safety of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes

Start date: October 30, 2006
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe. The aim of this research study is to compare the efficacy of adding inhaled preprandial insulin to metformin compared to adding rosiglitazone to metformin for the treatment of type 2 diabetes and to verify its safety (hypoglycaemia, pulmonary function, body weight, insulin antibodies and side effects).

NCT ID: NCT00327470 Terminated - Clinical trials for Macular Degeneration

An Open Label Trial to Investigate Macugen for the Preservation of Visual Function in Subjects With Neovascular AMD

PERSPECTIVES
Start date: July 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the benefits of treating subjects with neovascular age-related macular degeneration (AMD) at an earlier stage of choroidal neovascularization (CNV) as compared to those with established CNV. Additionally, the study would like to determine the efficacy of Macugen in preserving visual function in those subjects having CNV secondary to neovascular AMD.