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NCT ID: NCT06333600 Recruiting - Clinical trials for Female Pattern Baldness

Efficacy and Safety of Topical Vitamin D Analogue in Treatment of Female Pattern Hair Loss

Start date: May 20, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The trial aims to study efficay of topical vitamin D analogue in treatment of female pattern hair loss cases

NCT ID: NCT06332729 Recruiting - Cerebral Palsy Clinical Trials

Universal Exercise Unit Versus Functional Electrical Stimulation On Genu Recurvatum In Diplegic Cerebral Palsy

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

Summary: Inclusion Criteria: - Children aged four to eight years. - Grade of spasticity ranging from 1 to 1+ on the Modified Ashworth scale. - Classified as Level I or II on the Gross Motor Functional Classification System (GMFCS). - Ability to follow verbal commands and instructions. Exclusion Criteria: - Previous neurological or orthopedic surgery in the lower extremities. - Botox injection in the lower extremities within the past six months. - Fixed deformity in the joints of the lower limb. - Genu recarvatum secondary to surgery. - Severe hearing and visual defects. Materials for Subject Selection and Evaluation: - Modified Ashworth Scale for muscle tone assessment. - Gross Motor Functional Classification System (GMFCS) for functional activity classification. - Digital goniometer for measuring the angle of knee hyperextension. - Lafayette Manual Muscle Tester for quantifying muscle strength. Methods: - Assessment of muscle tone using the Modified Ashworth Scale, evaluating spasticity in calf muscles and hip/knee extensors. - Evaluation of gross motor function using the GMFCS. - Assessment of genu recarvatum using a digital goniometer. - Assessment of muscle strength using the Lafayette Manual Muscle Tester, focusing on hamstrings and tibialis anterior muscles. - Assessment of range of motion in the knee joint using Kinovea software. - Treatment procedures involving physical therapy sessions with a combination of exercises and interventions tailored to each group (Group A and Group B). Group A Treatment: - Designed physical therapy program combined with pulley therapy for muscle strengthening. Group B Treatment: - Designed physical therapy program combined with functional electrical stimulation during walking on a treadmill for muscle stimulation. The interventions in both groups aim to improve muscle strength, range of motion, and functional abilities in children with cerebral palsy.

NCT ID: NCT06331325 Recruiting - Clinical trials for High Frenum Attachment

Comparison of Frenotomy and Frenectomy Techniques for Management of High Frenum Attachment in Adults

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to compare frenotomy to frenectomy surgical techniques in the management of high frenum attachment in adults. The main questions it aims to answer are: - Does Frenotomy procedure have a lower relapse rate compared to frenectomy? - Does Frenotomy procedure result in fewer postoperative complications? Participants will be divided into two groups. The intervention group will involve frenotomy procedure for participants and will be compared to the traditional frenectomy procedure in the comparator group. The level of the frenum will be measured at baseline and after 6 months. Pain scores will be recorded by the participants during the first week.

NCT ID: NCT06331182 Recruiting - Dexmedetomidine Clinical Trials

Dexmedetomidine and Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain

Start date: March 26, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to compare the role of dexmedetomidine and ketamine as an adjuvant in external oblique intercostal plane block for post thoracotomy pain.

NCT ID: NCT06331143 Recruiting - Clinical trials for Idiopathic Scoliosis

Analgesic Efficacy of Mid-Transverse Process to Pleura (MTP) Block and Intrathecal Morphine in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion

Start date: March 28, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to compare the analgesic efficacy of mid-transverse process to pleura (MTP) block and intrathecal morphine in idiopathic scoliosis patients undergoing posterior spinal fusion surgery.

NCT ID: NCT06330935 Recruiting - Clinical trials for Traumatic Brain Injury

Evaluating the Effect of Tranexamic Acid on the Clinical Outcomes in Patients With Traumatic Brain Injury

Start date: March 25, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

Evaluate the effect of tranexamic acid on mortality in pediatric patients with traumatic brain injury. This could potentially lead to improved treatment protocols and better outcomes for this vulnerable population.

NCT ID: NCT06330571 Recruiting - Clinical trials for Orthodontic Aligners

The Efficiency of Clear Aligners in Maxillary Molar Distalization: A Randomized Clinical Trial.

Aligner
Start date: April 27, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the accuracy of clear aligners on the amount of the maxillary molar distalization.

NCT ID: NCT06330168 Recruiting - Thoracotomy Clinical Trials

Paravertebral Calcitonin in Thoracotomy

Start date: March 28, 2024
Phase: N/A
Study type: Interventional

This prospective randomized double-blinded controlled study will be conducted to evaluate the effect of adding calcitonin to bupivacaine in thoracic paravertebral block for patients undergoing thoracotomy.

NCT ID: NCT06329362 Recruiting - Alveolar Bone Loss Clinical Trials

Minimally Invasive Ridge Splitting Versus the Conventional Open Flap Technique

Start date: July 31, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare implant stability, and crestal bone loss, when using minimal invasive ridge splitting versus convenient open flap technique. The main question is Does Minimal Invasive Implant ridge splitting ("transmucosal" without flap) influence the implant stability and crystal bone loss, when compared with the conventional open flap techniques? Researchers will compare Group A: Minimal Invasive Implant ridge splitting and Group B: Triangular flap technique is used to see if there is significant difference between the two groups when measuring implant stability, and crestal bone density.

NCT ID: NCT06328322 Recruiting - Clinical trials for Left Main Coronary Artery Disease With Acute Coronary Syndrome

Study of Percutaneous Coronary Intervention in Left Main Coronary Artery Disease in Patients With Acute Coronary Syndrome at Sohag University Hospitals

Start date: April 1, 2024
Phase:
Study type: Observational

Acute coronary syndromes (ACS) encompass a spectrum of cardiovascular disorders characterized by the sudden onset of myocardial ischemia. They are primarily caused by atherosclerotic plaque rupture or erosion, leading to partial or complete occlusion of the coronary arteries. Among the various coronary arteries affected, left main coronary artery disease (LMCAD) is of particular concern due to its high anatomical significance and potential for adverse outcomes The left main coronary artery (LMCA) is responsible for supplying a substantial portion of the left ventricular myocardium, including the interventricular septum and the anterior and lateral walls. Any obstruction or compromise in blood flow within this critical artery can have severe consequences, including myocardial infarction, heart failure, or even sudden cardiac death. The management of LMCAD associated with ACS represents a significant clinical challenge, necessitating prompt and optimal treatment strategies Among the various coronary arteries affected by atherosclerosis, left main coronary artery disease (LMCAD) holds particular clinical significance due to its anatomical location and the vital role it plays in supplying a substantial portion of the left ventricular myocardium. The left main coronary artery (LMCA) typically bifurcates into the left anterior descending artery (LAD) and the left circumflex artery (LCX), which together provide blood supply to the majority of the left ventricle, including the interventricular septum and the anterior and lateral walls The selection of an appropriate treatment strategy for LMCAD associated with ACS is a complex decision that requires careful consideration of multiple factors, including patient characteristics, coronary anatomy, severity of ischemia, and procedural expertise. The emergence of several clinical trials and observational studies exploring the efficacy and safety of different revascularization strategies has further complicated the decision-making process