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NCT ID: NCT06467240 Not yet recruiting - Maxillary Anomaly Clinical Trials

Evaluation of the Hybrid Rapid Maxillary Expander Assisted With Micro-osteo Perforation (MOPs) in Adult.

Start date: July 1, 2024
Phase:
Study type: Observational

This study will be directed for Evaluation of the hybrid rapid maxillary expander assisted with Micro-osteo perforation (MOPs) in adults

NCT ID: NCT06466421 Not yet recruiting - Hemodialysis Clinical Trials

Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis

Start date: July 1, 2024
Phase: Phase 4
Study type: Interventional

Several studies investigated the effectiveness of Gabapentin in Uremic Pruritus (UP). No previous studies investigated the use of fexofenadine in UP. The aim of this trial is to assess the safety and possible efficacy of fexofenadine in patients with UP.

NCT ID: NCT06464380 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

Anti-cancer Potentiality of Saffron Against Hepatocellular Carcinoma

Start date: July 30, 2024
Phase: Phase 4
Study type: Interventional

Saffron has recently gained considerable interest for its capacity to interfere with cancer at initiation and promotion stages as well as for cancer treatment. Although saffron and its constituents have been shown to have antitumorigenic and proapoptotic activities in different cancer cell lines. The aim of the current investigation is to identify the anti-cancer potentiality of saffron on hepatocellular carcinoma patients.

NCT ID: NCT06457672 Not yet recruiting - Gingival Recession Clinical Trials

Assessment of The Accuracy of Complete Crown 3D Superimposition Technique Relative to The Gold Standard Technique for Digital Quantification of Volumetric Soft Tissue Changes in The Esthetic Zone

Start date: June 15, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to assess the precision of the complete crown technique employed for the superimposition of 3D models, specifically in the quantitative volumetric evaluation of gingival tissues. This technique was initially introduced in an in-vitro study by Dritsas et al. (2023) as a means to achieve an accurate, reproducible, and simple method for quantification of gingival recession.

NCT ID: NCT06457373 Not yet recruiting - Alveolar Bone Loss Clinical Trials

Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation

Start date: July 1, 2024
Phase: N/A
Study type: Interventional

This study is designed to evaluate and compare clinically and radiographically the effectiveness of Demineralized Dentin Allograft (DDA) versus Demineralized Dentin Autograft (Auto-DD) for preservation of alveolar ridge dimensions after surgical extraction of the impacted mandibular third molar.

NCT ID: NCT06456944 Not yet recruiting - Plantar Fascitis Clinical Trials

Effect of Selected Rehabilitation Program in Patients With Plantar Fasciitis

Start date: June 15, 2024
Phase: N/A
Study type: Interventional

This study will be done to investigate the effect of the selected rehabilitation program for PF on plantar fascia thickness, clinical outcomes such as pain, foot function, dorsiflexion ROM and pressure pain threshold and alignment such as rearfoot eversion angle and foot posture index in patients with PF.

NCT ID: NCT06453252 Not yet recruiting - Stroke, Ischemic Clinical Trials

Predictors of Intracranial Atherosclerotic Disease in Posterior Circulation: a Cohort Study

Start date: June 15, 2024
Phase:
Study type: Observational

Early identification of intracranial atherosclerotic disease (ICAD) may impact the management of patients undergoing mechanical thrombectomy (MT). The aim of the study is to develop and validate a scoring system for pre-thrombectomy diagnosis of ICAD in posterior circulation large vessel/distal medium vessel occlusion strokes (LVOs/DMVOs).

NCT ID: NCT06452511 Not yet recruiting - PCOS Clinical Trials

Comparing the Effect of Metformin vs. Pep2dia as an Adjunct to Letrozole on Ovulation Induction and Pregnancy Outcomes in Overweight Women With PCOS

Start date: July 1, 2024
Phase: Early Phase 1
Study type: Interventional

The goal of this clinical trial is to compare the effects of Metformin versus Pep2dia as adjunct treatments to Letrozole on ovulation induction and pregnancy outcomes in overweight women with polycystic ovary syndrome (PCOS). The main questions it aims to answer are: Does Metformin improve ovulation rates more effectively than Pep2dia when used alongside Letrozole? Does Pep2dia enhance pregnancy outcomes compared to Metformin in this patient population? Participants will: Receive either Metformin or Pep2dia in addition to Letrozole. Undergo regular monitoring for ovulation and pregnancy outcomes. Researchers will compare the Metformin group to the Pep2dia group to see if there is a significant difference in ovulation and pregnancy rates between the two treatments.

NCT ID: NCT06451276 Not yet recruiting - Clinical trials for Cleft Lip and Palate

The Effectiveness of Adhesive Versus Conventional Nasoalveolar Molding on Children With Unilateral Cleft Lip and Palate

Start date: July 20, 2024
Phase: N/A
Study type: Interventional

The present study will compare the effectiveness of adhesive nasoalveolar molding (GS-NAM) and conventional nasoalveolar molding on the alveolar ridge, nasal, and labial growth in children with unilateral cleft lip and palate. objectives: - 1. Evaluation of the anatomical position of the greater and lesser segments of the maxilla related to a stable midline anatomical point. 2. Evaluation of the nasal symmetry.

NCT ID: NCT06451224 Not yet recruiting - Clinical trials for Infections Joint Prosthetic

Egyptian Arthroplasty Surgeons' Antibiotics Usage Awareness

Start date: June 15, 2024
Phase:
Study type: Observational

Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are procedures successfully applied to manage various end-stage chronic hip and knee diseases, such as osteoarthritis, rheumatoid arthritis, and femoral head avascular necrosis, as well as acute conditions, such as the neck of femur fractures, with excellent long-term functional outcomes. One of the devastating complications after such a procedure is periprosthetic joint infection (PJI). Various precautions are proposed to guard against such complications; one is the administration of perioperative antibiotics. However, injudicious or misuse of antibiotics could lead to the emergence of antimicrobial resistance, further complicating this matter. This is why various scientific and research organizations have proposed guidelines and a consensus for proper antibiotic use in perioperative THA and TKA surgery. Antibiotic prophylaxis during primary THA and TKA can reduce the risk of PJI and surgical site infections. However, there is a lack of consensus on the optimal dosages and duration of prophylaxis, and guidelines vary among institutions. Alternatives such as extended oral antibiotic prophylaxis and different antibiotic regimens are being explored. International research is needed to establish best practices and determine the potential risks of antibiotic prophylaxis during primary THA and TKA. Unfortunately, the investigators are unaware of such guidelines proposed by any Egyptian health authority to guide and control the proper utilization of antibiotics during orthoapedic practice in general and joint replacement surgeries (THA and TKA) in particular.