Paravertebral Calcitonin in Thoracotomy

Status Recruiting

Clinical Trial Summary

This prospective randomized double-blinded controlled study will be conducted to evaluate the effect of adding calcitonin to bupivacaine in thoracic paravertebral block for patients undergoing thoracotomy.

Clinical Trial Description

Single-shot thoracic paravertebral block combined with intravenous analgesia is one of the regional techniques used for controlling pain in patients undergoing thoracic surgery. However, few articles demonstrated its effects on acute pain and chronic pain after thoracotomy and revealed high postoperative opioid consumption and inability to reduce the incidence of chronic pain. Calcitonin has previously been shown to be effective in the management of acute pain following amputation, vertebral fractures and other neuropathic conditions. Using calcitonin as an additive in thoracic paravertebral block was not evaluated in previous studies, we conducted this study as we hypothesize that calcitonin use as an additive in thoracic paravertebral block for patients undergoing thoracotomy may have extended analgesic effects regarding decreasing postoperative pain scores, opioid consumption, and this value may decrease the incidence of chronic post-thoracotomy pain. In both groups, ultrasound-guided thoracic paravertebral block will be performed before anesthetic induction using a high-frequency linear probe after identifying the paravertebral space of the proposed level of intercostal skin incision.General anesthesia in both groups will be similar. ;

Study Design

Related Conditions & MeSH terms

Thoracotomy

Clinical Trial Details

NCT number	NCT06330168
Study type	Interventional
Source	Tanta University
Contact	Osama M Rehab, MD
Phone	01095210806
Email	osamarehab@med.tanta.edu.eg
Status	Recruiting
Phase	N/A
Start date	March 28, 2024
Completion date	April 10, 2025

View Details

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