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Idiopathic Scoliosis clinical trials

View clinical trials related to Idiopathic Scoliosis.

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NCT ID: NCT06331143 Not yet recruiting - Clinical trials for Idiopathic Scoliosis

Multiple Mid-Transverse Process to Pleura (MTP) Block and PCA in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion

Start date: March 30, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to compare the analgesic efficacy of mid-transverse to pleura (MTP) block and patient-controlled analgesia (PCA ) in idiopathic scoliosis patients undergoing posterior spinal fusion surgery.

NCT ID: NCT06298812 Not yet recruiting - Clinical trials for Idiopathic Scoliosis

REFLECT Scoliosis System Post Approval Study

Start date: March 31, 2024
Phase: N/A
Study type: Interventional

The purpose of this multi-center, prospective, single-arm registry Post-Approval Study (PAS) is to evaluate the radiographic and clinical outcomes of 100 patients with idiopathic scoliosis treated with the REFLECTâ„¢ Scoliosis Correction System, as a condition of HDE approval

NCT ID: NCT06290843 Not yet recruiting - Clinical trials for Idiopathic Scoliosis

Analysis of Body Balance Parameters in Children With Idiopathic Scoliosis

Start date: March 15, 2024
Phase:
Study type: Observational

The aim of the study is to compare body balance parameters assessed using the AMTI dynamometric platform in children with idiopathic scoliosis (with and without Schroth therapy) compared to control group.

NCT ID: NCT06219772 Not yet recruiting - Clinical trials for Idiopathic Scoliosis

Assessment of Dynamic Balance in Idiopathic Scoliosis Compared to Normal Subjects

Start date: February 2024
Phase:
Study type: Observational

The purpose of this study is to assess dynamic balance in females with adolescent idiopathic scoliosis compared to normal subjects.

NCT ID: NCT06194279 Recruiting - Clinical trials for Idiopathic Scoliosis

Analysis of Different Postoperative Analgesia Strategies Following Scoliosis Surgery

SAPOS
Start date: June 19, 2023
Phase:
Study type: Observational

Idiopathic scoliosis surgery is a major surgery, causing significant post-operative pain which can have a significant impact, both for the patient and for society. Different analgesic strategies have emerged in recent years, within the framework of multimodal analgesia including systemic analgesics, but also axial or peripheral loco-regional anesthesia (LRA). These techniques are integrated into the recommendations of learned societies, aimed at optimizing the post-operative rehabilitation of patients. If intrathecal morphine injection (ITM) and spinal erector block (ESPB) have already shown their effectiveness in reducing postoperative pain, the combination of these techniques can have a real benefit in major spinal surgery. , and has not yet been studied.

NCT ID: NCT06161038 Recruiting - Rehabilitation Clinical Trials

Precision Medicine for Nociception, Sngception and Proprioception.

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Precision medicine is defined as "an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person" by the Precision Medicine Initiative. Patients have different response to different treatment modalities, and sore/pain medicine is no exception. In our experience, low-level laser (LLL), ultrasound, and prolotherapy can reduce sore /pain through different genetic pathway. Whether the therapeutic effect is controlled by the genetic variants of those sore /pain related genes or not, is still in debate. The aims of this study are (1) To set up next generation sequencing (NGS)-based approach to find genetic variants which can determine the response of sng/pain treatment modalities and the phenotype of idiopathic scoliosis. (2) To find possible metabolomics and proteomic markers of sng/pain. (3) To determine the algorithm of precision medicine for sng/pain control via the genetic markers. Investigators will recruit 80 myofascial pain participant and 80 idiopathic scoliosis participant from Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital Bei-Hu Branch in 2023 and 2025. The myofascial pain participant participants will receive LLL, ultrasound, and prolotherapy, and the therapeutic effect will be recorded. The clinical trial will evaluate the Sng / pain (VAS) and muscle tone of the idiopathic scoliosis participant. The blood and urine samples from the first, the second, and the third visits will be analyzed by next generation sequencing, and mass spectrometry to find the possible biomarker in 2024 and 2025. Investigators expect to develop the individualized treatment plan by means of these biomarkers. Hopefully, the results will be widely applied in the field of sore /pain medicine.

NCT ID: NCT06152601 Recruiting - Clinical trials for Idiopathic Scoliosis

Early Standing in Minors Operated on for Idiopathic Scoliosis

LevPOS
Start date: March 19, 2024
Phase: N/A
Study type: Interventional

The implementation of an enhanced rehabilitation after surgery (ERAS) program in major orthopedic surgery and in scoliosis surgery in children and adolescents has become a marker of good practice. Investigators are already applying anesthetic, surgical, peri-operative medicine and rehabilitation techniques allowing accelerated and improved rehabilitation for scoliosis operated patients in the establishment. To improve patient care, the Investigators want to develop the ERAS program. The objective of this research will be to validate the feasibility of getting up early on D0 in post-anesthesia care unit (PACU) or ICU in children who have just had surgery for idiopathic scoliosis.

NCT ID: NCT06055140 Not yet recruiting - Pain Clinical Trials

Evaluation of Thoracolumbar Fascia and Relationship With Low Back Pain in Individuals With Idiopathic Scoliosis

Start date: October 1, 2023
Phase:
Study type: Observational

This observational study seeks to explore the potential association between thoracolumbar fascia characteristics and low back pain in individuals diagnosed with idiopathic scoliosis.

NCT ID: NCT06006897 Recruiting - Clinical trials for COVID-19 Respiratory Infection

Pain, Physical Activity, Posture and Quality of Life in Post-COVID-19 Individuals With Idiopathic Scoliosis

Start date: June 16, 2023
Phase:
Study type: Observational [Patient Registry]

It is not known to what extent the COVID-19 virus affects individuals with scoliosis during the prolonged COVID-19 pandemic. Therefore, in this study it was aimed to comparatively investigate pain severity, posture disorders that can be assessed by artificial intelligence, physical activity levels and quality of life in individuals with idiopathic scoliosis with and without COVID-19.

NCT ID: NCT05956899 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Palonosetron vs Ondansetron In PONV Prophylaxis Among Idiopathic Scoliosis Patients

PONV
Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to compare the effectiveness of two antiemetic drugs, palonosetron and ondansetron, when given alongside dexamethasone as a preventive measure against early and delayed postoperative nausea and vomiting (PONV) in adult and adolescent patients with idiopathic scoliosis undergoing posterior spinal fusion surgery under total intravenous anesthesia (TIVA). The main questions the study aims to answer are: - How effective is palonosetron compared to ondansetron, both combined with dexamethasone, in preventing PONV after scoliosis surgery? - Are there any differences in the need for rescue antiemetics, occurrence of adverse effects related to the study drugs, and patient satisfaction between the two treatment groups? Participants in the study will be randomly assigned to receive either palonosetron or ondansetron in addition to dexamethasone as part of their anesthesia and antiemetic regimen. The incidence and/ or severity of nausea, vomiting and retching will be assessed at 1 hour, 4 hours, 12 hours, 24 hours and 48 hours after surgery.