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NCT ID: NCT03257930 Recruiting - Thyroid Nodule Clinical Trials

Percutaneous Ethanol Injection for Benign Cystic Thyroid Nodules

Start date: August 11, 2017
Phase: Phase 1
Study type: Interventional

Use of ethanol injection in treatment of cystic thyroid nodule

NCT ID: NCT03256669 Enrolling by invitation - Neonatal Surgery Clinical Trials

Umblical Incision for Neonatal Surgery

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Abdominal exploration leave an ugly scar that live with the baby forever, laparoscopy can solve the problem to some extent by making a smaller scar but takes more time and need special surgical skills. Umbilical incision can combine the advantage of open and laparoscopy and avoid the drawbacks of both.

NCT ID: NCT03255707 Recruiting - Amblyopia Clinical Trials

A Comparative Study Between Dissociative Treatment and Binocular Interactive Treatment in Amblyopia

Start date: November 24, 2016
Phase: N/A
Study type: Interventional

Amblyopia is a unilateral or, infrequently, a bilateral reduction of best corrected visual acuity which cannot be attributed to coexisting eye or visual pathway disease. Amblyopia can be due to eye-crossing occurring in early childhood or due to error of refraction whether a high difference between the two eyes or very high bilateral refractive errors.Another cause could be visual deprivation like the presence of congenital cataract. The prevalence of amblyopia worldwide is approximately 1%-5% .In Egypt, a study that was held in Upper Egypt, found that the prevalence of amblyopia was 1.49%, which is higher in rural areas than in urban areas. Several modalities of treatment for amblyopia are available, yet occlusion treatment is the gold standard involving covering the good eye with a patch for a prescribed period of time ranging from 10 minutes daily to all waking hours. However, its effectiveness decreases in older children and adults. Disadvantages include prolonged treatment leading to poor compliance, patching related distress, relationship strain and stigma. In extreme cases, non-compliance with patching results in a costly hospital admission to supervise the patching treatment. In addition, wearing a patch eliminates any advantage of binocularity. Not to mention that not all patients respond to patching and of those who do, many have residual amblyopia after treatment is stopped regardless of compliance. More importantly, binocular vision is not automatically restored once the vision in the amblyopic eye has been improved. In fact, once the patch is removed after therapy, the amblyopic eye could be suppressed by the better seeing eye and can lose some of the gains achieved as a result of therapy. Another modality of treatment is atropine eye drops and optical penalisation which are usually secondary treatments to failed patching but carrying the same disadvantages as the ordinary patching. Advances in amblyopia treatment include dichoptic training, perceptual learning, and video gaming. These depend on the fact that the adult brain has been shown to be much more plastic than it was once believed to be and hence have the advantage of expanding the age of response in adults. Perceptual learning approaches have the advantage of being a dichoptic (binocular treatment using both eyes) approach which is independent of age and type of amblyopia. A step further to conventional treatment is the use of a home-based approach allowing remote internet monitoring of treatment between office visits and hence better compliance. In addition a video game version of the treatment is developed to make it more enjoyable for improving compliance. Our goal is to compare the outcome between the gold standard occlusion therapy and one of the dichoptic treatments.

NCT ID: NCT03255044 Recruiting - Heart Failure Clinical Trials

Comparison of Lipophilic Versus Hydrophilic Statins on Patients With Heart Failure

Start date: June 15, 2017
Phase: Phase 4
Study type: Interventional

There is a controversy whether statins are beneficial in patients with heart failure or not. Trials in which lipophilic statins have been used revealed positive results, unlike major studies where hydrophilic statins were administered. This trial is designed to compare the effects of lipophilic versus hydrophilic statin use in patients with heart failure.

NCT ID: NCT03254901 Not yet recruiting - Hepatitis C Clinical Trials

Detection of Hepatitis C Infection by Oraquick Test Among Health Care Workers

Start date: January 1, 2018
Phase: N/A
Study type: Observational

Viral hepatitis is a global health problem affecting hundred millions of people worldwide and considered the main cause of liver cirrhosis, hepatocellular carcinoma and liver transplantation in developing countries.

NCT ID: NCT03254888 Not yet recruiting - Bladder Cancer Clinical Trials

Autophagy Bladder Cancer

Start date: October 1, 2017
Phase: N/A
Study type: Observational

Bladder cancer is the most common malignancy of the urinary tract. It is characterized by multiple growths that tend to recur in a more aggressive form, making it an economic burden due to its high cost per patient in medical treatment . It represents the 7th most commonly diagnosed cancer in male population worldwide and drops to the 11th when both genders are considered

NCT ID: NCT03253562 Completed - Clinical trials for Reducing the Elevated Blood Pressure for Diabetic Hypertensive Patients

Metformin Versus Vildagliptin for Diabetic Hypertensive Patients

Start date: February 1, 2017
Phase: Phase 4
Study type: Interventional

This is a controlled study to measure the efficacy of using metformin or vildagliptin for type 2 diabetic patients who suffers from hypertension to reduce cardiovascular risk resulting from both diabetes and hypertension using different parameters measuring

NCT ID: NCT03253510 Not yet recruiting - Complete Edentulism Clinical Trials

Measuring Biting Force of Poly-amide Complete Dentures

Start date: September 2017
Phase: N/A
Study type: Interventional

Randomized clinical trial to compare between biting force of mandibular complete denture constructed from two different materials; metal reinforced polyamide and conventional PMMA,The null hypothesis of the study that there will not be a difference between biting force of the complete denture constructed from metal reinforced polyamide and PMMA

NCT ID: NCT03253315 Not yet recruiting - Pericarditis Clinical Trials

Management of Pericarditis in Children.

Start date: September 2017
Phase: N/A
Study type: Observational [Patient Registry]

The pericardium is a double-walled sac containing the heart and the roots of the great vessels. The pericardial sac has two layers, a serous visceral l layer (also known as epicardium when it comes into contact with the myocardium) and a fibrous parietal layer. It encloses the pericardial cavity, which contains pericardial fluid. The pericardium fixes the heart to the mediastinum, gives protection against infection and provides lubrication for the heart. Pericardial diseases may be either isolated disease or part of a systemic disease Diseases of the pericardium present clinically in one of several ways - Acute and recurrent pericarditis - Pericardial effusion without major hemodynamic compromise - Cardiac tamponade with cardiac compromise - Constrictive pericarditis

NCT ID: NCT03252496 Recruiting - Cesarean Section Clinical Trials

Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery

Start date: August 19, 2017
Phase: N/A
Study type: Interventional

This study will compare between combination of colloids/crystalloids and crystalloids in women with preeclampsia undergoing elective cesarean delivery under spinal anesthesia