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NCT ID: NCT03922295 Completed - Clinical trials for Tympanic Membrane Perforation

Endoscopic Tympanoplasty: Single Versus Double Flap Technique

Start date: August 24, 2017
Phase: N/A
Study type: Interventional

Aim of this study is to compare results of double and single flap techniques for tympanoplasty in chronic suppurative otitis media patients. Inclusion criteria include total or subtotal tympanic membrane perforations with limited anterior remnant and should be dry for at least 3 months. Patients with persistent discharge, cholesteatoma, ossicular affection or those with recurrent perforations after previous myringoplasty were excluded. Also, patients with uncontrolled diabetes, chronic liver and kidney diseases and immuno-compromised patients are not included in this study. Patients are divided into two groups, endoscopic double flap group and endoscopic single flap group. Healing and hearing outcomes were evaluated 3 months postoperative. Also, post-operative pain scores and complications were assessed.

NCT ID: NCT03921125 Recruiting - Fluid Response Clinical Trials

Pleth Variability Index for Directed Fluid Optimization in Donors in Living Donor Liver Transplantation

Start date: October 9, 2018
Study type: Observational

In this Study we are trying to validate the accuracy of Plethogram variability index in predicting fluid responsiveness compared to pulse pressure variation in donors of liver transplantation

NCT ID: NCT03921112 Active, not recruiting - Clinical trials for Intensive Care (ICU)

Role of Lung Ultrasound in Weaning From Mechanical Ventilation in Postoperative Neurosurgical ICU Patients

Start date: April 3, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to demonstrate the role of lung ultrasound in weaning from mechanical ventilation in neurosurgical ICU patients compared to the ordinary tools as chest X-ray , ABG, rapid shallow breathing index, ventilator parameters.

NCT ID: NCT03921099 Recruiting - Acute Kidney Injury Clinical Trials

Impact of Ascorbic Acid in the Prevention of Vancomycin Induced Nephrotoxicty

Start date: January 17, 2019
Phase: Phase 4
Study type: Interventional

A Randomized controlled trial aiming to investigate whether ascorbic acid has a role in preventing vancomycin induced nephrotoxicity or not in critically ill patients.

NCT ID: NCT03920449 Recruiting - Clinical trials for Chronic Anal Fissure

Postero-lateral Internal Sphincterotomy vs Botulinum Toxin Injection in the Treatment of Chronic Anal Fissure: A Randomized Controlled Trial

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

We hypothesized that optimization of the dose of the Botulinum toxin injection (BT) and standardization of the technique of lateral internal sphincterotomy to posterolateral internal sphincterotomy (PIAS) could, in turn, report a conclusive result which helps to provide better care to patients with chronic anal fissure. So, we will conduct this trial as a prospective randomized, controlled, intervention, open-label trial with two parallel groups, and a primary endpoint of fissure healing during 6 months after the initial intervention, with the randomization, will be performed by an online software with a 1:1 allocation. Eligible patients will be randomized in equal proportions between BT injection and PIAS.

NCT ID: NCT03918200 Completed - Infertility Clinical Trials

Serum Amyloid A in Women With Unexplained Infertility

Start date: October 1, 2018
Study type: Observational

High follicular fluid amyloid A level is associated with reduced pregnancy rate. The aim of this study was to find an association between serum level of amyloid A and unexplained infertility.

NCT ID: NCT03918187 Active, not recruiting - Clinical trials for Cesarean Section Pain

Nalbuphine Versus Midazolam as an Adjuvant to Intrathecal Bupivacaine for Postoperative Analgesia in Patients Undergoing Cesarean Section

Start date: March 17, 2019
Phase: Phase 1
Study type: Interventional

Adequate pain management is important to facilitate the functional recovery and enable the patients for rapid rehabilitation of normal activity . Various adjuvants were being used with intrathecal bupivacain to prolong & improve postoperative pain relief in patients undergoing cesarean section . In this study the investigator will compare the duration of postoperative analgesia and side effects of adding nalbuphine or midazolam as adjuvants to intrathecal bupivacain in patients undergoing cesarean section .

NCT ID: NCT03917940 Recruiting - Diabetic Patients Clinical Trials

Omega 3 Fatty Acids on Serum Irisin and Sirtuin-1 in Type 2 Diabetic Mellitus Patients Treated With Glimepiride

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

study the effect of omega 3 fatty acids on blood glucose, lipids profile, serum Irisin and sirtuin-1 in type 2 diabetic mellitus patients treated with glimepiride.

NCT ID: NCT03916536 Recruiting - Holmium Laser Clinical Trials

Holmium Laser Versus Thulium Laser Versus Bipolar Enucleation of the Prostate.

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Because of the diversity of the studies and deficiency of those comparing various techniques of EEP for treatment of LUTs secondary to BPO in patients with large sized prostate, we aim in this study at testing the non-inferiority of PKEP and ThuLEP to HoLEP in relieving LUTs secondary to BPO in patients prostate size >80ml. Our hypothesis is to present an evidence that enucleation is a technique rather than a power dependent procedure through a RCT.

NCT ID: NCT03915990 Not yet recruiting - Clinical trials for Diabetes Mellitus, Type 1

Middle Cerebral and Umbilical Arteries Doppler Indices in the Prediction of Adverse Neonatal Outcome Among Diabetic Pregnant Women

Start date: May 2019
Phase: N/A
Study type: Interventional

120 patients will be included and divided into two groups; Control group that will include 60 healthy pregnant women and Study group that will include 60 pregestational diabetic pregnant patients which furtherly will be subdivided into two groups according to HbA1C levels namely; controlled diabetics ( will include 30 diabetic pregnant women with controlled DM - HbA1C < 6.5 %) and uncontrolled diabetics (will include 30 diabetic pregnant women with uncontrolled DM - HbA1C ≥ 6.5 %). Umbilical and middle cerebral arteries Doppler indices (resistance index and pulsatility index) and Cerebroplacental Doppler ratio will be measured for every patient. The recorded neonatal outcomes will include neonatal birth weight, neonatal blood sugar, Apgar score at 1 & 5 min and neonatal intensive care unit admission.