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NCT ID: NCT04850859 Not yet recruiting - Glenoid Cavity Clinical Trials

Study on Human Glenoid Cavity and Acetabulum

Start date: June 1, 2021
Phase:
Study type: Observational

1 - study morphological and morphometric features of the glenoid cavity in human scapulae bone and its function. 2- study morphological and morphometric features of the acetabulum in human hip bone and its function.

NCT ID: NCT04850365 Recruiting - Clinical trials for Pelvic Organ Prolapse

Abdominal Sacral Hysteropexy Versus Vaginal Sacrospinous Hysteropexy

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The aim of the current study is to compare abdominal sacral cervicopexy with vaginal sacrospinous cervicopexy in women with apical prolapse in terms of operative time, procedures safety and efficacy.

NCT ID: NCT04849663 Completed - Gingival Recession Clinical Trials

Comparative Evaluation of Buccal Fat Pad and Subepithelial Connective Tissue Graft

RCT
Start date: June 24, 2018
Phase: Early Phase 1
Study type: Interventional

Compare between Buccal fat pad and subepithelial connective tissue graft in treatment of localized recession. Primary objective: to evaluate root coverage in terms of gingival thickness and esthetic. Secondary objective: to evaluate patient satisfaction and postoperative pain.

NCT ID: NCT04849442 Completed - Clinical trials for Musculoskeletal Pain

Association of Jaw Dysfunction With Neck Disability in Subjects With Chronic Cervical Spine Disorders

Start date: June 1, 2019
Phase:
Study type: Observational

Since TMJ and cervical pain incidence are rising and both structures are highly interrelated anatomically and functionally. And yet no standard protocol for TMD therapy The objective of this study is to state if there is a correlation between TMD and cervical dysfunction. To help reach a better diagnosis and a more holistic treatment. Forty volunteers (15 male and 25 female) between the ages of 20 to 40 were recruited. Cervical ROM was measured in all directions (rotation, flexion and extension, and sidebending) by CROM device, and a 10 cm plastic ruler marked in both centimeters and millimeters was used to measure TMJ vertical opening.

NCT ID: NCT04849338 Recruiting - Clinical trials for Von Willebrand's Diseased Children, Bleeding Questionnaire is Done

The Role of Standardized Bleeding Score in Diagnosis of Pediatric Von Willebrand's Disease

Start date: April 15, 2021
Phase:
Study type: Observational

Von Willebrand's disease (VWD) is the most common inherited bleeding disorder. It arises from a deficiency in the quality or quantity of von Willebrand factor (VWF), a multimeric protein that is required for platelet adhesion. Typical patients present with mucocutaneous bleeding symptoms because of reduced circulating von Willebrand factor (VWF) In this study we will use the ISTH/SSC BLEEDING assessment tool as a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders

NCT ID: NCT04848987 Completed - Dental Leakage Clinical Trials

Indirect Resin Composite Inlays Cemented With a Self-adhesive, Self-etch or a Conventional Resin Cement

Start date: October 10, 2016
Phase: N/A
Study type: Interventional

The present study was designed to provide further evidence in this particular research prospective, and this study hence aimed to clinically evaluate the 5-years adhesion durability of indirect resin composite inlays luted with three different resin cement strategies in MOD Class II restorations. The formulated null hypothesis was that there is no significant difference in the clinical performances of the three different resin cement strategies for luting indirect resin composite inlays in MOD Class II restorations for 5-years. The research question was as follows: Do self-adhesive resin cements in class II restorations present better clinical performances than conventional etch-and-rinse and self-etch resin cements according to the USPHS criteria?

NCT ID: NCT04848181 Not yet recruiting - Clinical trials for Prostate Hyperplasia

The Effect of Pre-operative Use of Finasteride Versus Cyproterone Acetate on Blood Loss With Transurethral Resection of Prostate

Start date: May 1, 2021
Phase: Early Phase 1
Study type: Interventional

Perioperative bleeding is the most common complication related to transurethral resection of prostate, the aim of the study is to compare the effect of pre-operative use of finasteride versus Cyproterone acetate on blood loss with mono polar TURP

NCT ID: NCT04847661 Recruiting - Covid19 Clinical Trials

Efficacy of Mefloquine as Prophylaxis Against COVID-19: A Placebo-control, Randomized Clinical Trial

Start date: March 28, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this study is to evaluate the efficacy and safety of Mefloquine as a prophylaxis against SARS-Cov-2 infection in household contacts of COVID 19 confirmed. This study is an open-label, randomized, placebo controlled trial. A total of 1500 household contacts of COVID-19 confirmed cases who will attend triaging clinic of 5 Egyptian university centers (Helwan university hospital, Ain Shams university hospital, Assiut University Hospital, Fayoum university hospital and Tanta university hospital). The household contacts of COVID-19 confirmed subjects with a decision for home-isolation will be recruited to participate into this study. The recruited subjects from each center will be randomly assigned (locally in that center) into 2 groups (750 volunteer in each group). The 1st group will receive Mefloquine (1100-1650 mg according to body weight), orally, while the other group will receive the same number of placebo tablets (control group). Previous infection will be excluded for all recruited subjects by testing for the presence of anti-bodies against COVID-19 to exclude previous infection. Subjects who are tested negative will be allocated into one of the 2 study groups after randomization, and treatment will be started immediately (either mefloquine or placebo). In addition, a nasopharyngeal swap will be taken from each recruited subject and tested by PCR for COVID-19 to exclude current infection. After having the PCR results, positive cases will be analyzed separately to test for the disease severity. Neurological and cardiac assessment will be done for all volunteers before recruitment to exclude the presence of any contraindication for Mefloquine intake. Both groups will be followed up clinically to detect any symptom or sign of COVID-19 infection for 2 weeks (during the period of home isolation). Nasopharyngeal swap with PCR for COVID-19 will be done for all included subjects at the end of the follow-up period (14 days), or at the appearance of symptoms or signs suggesting COVID-19 infection. Primary end points of the study are either: - End of follow up period (2 weeks) - Confirmed diagnosis of COVID-19 infection during the study time Initial severity assessment of COVID-19 infection will be done in all infected subjects in both groups to compare severity, in addition to following up of the fate of the infected subjects.

NCT ID: NCT04847414 Active, not recruiting - Clinical trials for Diabetes Mellitus, Type 2

Novel Classification of Adult-onset Diabetes and Its Association With Common Microvascular Complications in Upper Egypt

Start date: April 10, 2021
Phase:
Study type: Observational

Aim of our work: First aim: Classify patients with adult-onset diabetes according to the novel classification into new subgroups, depending on multiple variables related clinically to those patients. Second aim: To identify the association between the new classification subgroups and the presence of common microvascular complications (retinopathy, nephropathy, and neuropathy), which can help in the early prediction of these complications and their early management.

NCT ID: NCT04846699 Not yet recruiting - Endourology Clinical Trials

Triangulation Bulls Eye and Stone Direct Targeting Pcnl

Start date: April 20, 2021
Phase:
Study type: Observational

To assess the impact of percutaneous renal access technique on outcomes of percutaneous nephrolithotomy in management of renal stones by comparing the Triangulation and ''eye of the needle'' (or bull's eye) and the stone targeted techniques in the following:- 1. Stone free rate (SFR) (primary outcome). 2. Complicatins of surgery (primary outcome). 3. Change in haematocrit pre and postoperative (secondary outcome). 4. Operative time (secondary outcome). 5. Duration of hospitalization (secondary outcome). . 7-Fluroscpic screening time (FST) (secondary outcome). . 8- Change in haematocrit pre and postoperative (secondary outcome).