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NCT ID: NCT05738265 Active, not recruiting - Shock Clinical Trials

Fluid Resuscitation In Trauma: What Are The Best Strategies And Fluids?

Start date: August 1, 2022
Phase:
Study type: Observational [Patient Registry]

Illustration of the differential effects of commonly used resuscitation fluids, including isotonic crystalloids, natural and artificial colloids, hypertonic and hyperoncotic solutions to prevent the cellular injury through wiser resuscitation in traumatic patient . The ideal resuscitation strategy for multiply injured patients.

NCT ID: NCT05735197 Active, not recruiting - Clinical trials for Chronic Kidney Diseases

Effect of Dapagliflozin on Renal Outcomes and Bone Mineral Disease in Non-diabetic Chronic Kidney Disease Patients

Start date: November 10, 2022
Phase: Phase 4
Study type: Interventional

It is a randomized controlled trial in which 100 non diabetic chronic kidney disease (CKD) patient is being participated. Their estimated glomerular filtration rate (eGFR) between 25-75 ml/min/1.73 m2. Participants will be randomized into two groups: - Study group: includes 50 patients, they will receive Sodium glucose co-transporter 2 inhibitor (SGLT2i) as add on drug, Dapagliflozin 10 mg will be used once daily with or without food. - Control group: includes 50 patients, they will receive placebo their medication. The investigators will follow up all patients for 12 months and compare their results. This study aims to: 1. Assess SGLT2i role in delaying the progression of ongoing chronic kidney disease. 2. Study the impact of SGLT2i on bone and mineral metabolism in this patients' population.

NCT ID: NCT05735067 Active, not recruiting - Multiple Sclerosis Clinical Trials

The Impact of Body Weight on Clinical and Immunological Outcomes in Relapse-Remitting Multiple Sclerosis Patients

Start date: February 1, 2022
Phase:
Study type: Observational [Patient Registry]

Our study aimed to investigate the effect of interferon beta 1a on the clinical and immunological parameters in Egyptian relapse-remitting multiple sclerosis patients

NCT ID: NCT05733936 Active, not recruiting - Rehabilitation Clinical Trials

Biomechanical Determinants of Different Rehabilitation Protocols for ACL Reconstruction

Start date: February 20, 2023
Phase: N/A
Study type: Interventional

Purpose of the study is to investigate the effects of the criterion rehabilitation protocol versus accelerated rehabilitation protocol on the biomechanical determinants of the quality of performance and risk of reinjury.

NCT ID: NCT05727423 Active, not recruiting - Heart Failure Clinical Trials

Dapagliflozin in the Treatment of Heart Failure

Start date: September 1, 2021
Phase:
Study type: Observational

prospectively evaluation the safety and efficacy of the Sodium-glucose Cotransporter-2 (SGLT2) inhibitor dapagliflozin in non-diabetic patients with heart failure and a reduced ejection fraction

NCT ID: NCT05727124 Active, not recruiting - Canine Retraction Clinical Trials

Poul Gjessing Versus T Loops for Orthodontic Maxillary Canine Retraction

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

Poul Gjessing versus T loops for orthodontic maxillary canine

NCT ID: NCT05713084 Active, not recruiting - Clinical trials for Maxillofacial Abnormalities

Condylar Position Changes and TMJ Functions After BSSO Mandibular Setback, Low Medial Cut.

Start date: September 28, 2022
Phase: N/A
Study type: Interventional

This study hypotheses that using low medial cut osteotomy BSSO in mandibular setback can be an efficient and effective method to limit the bony segment interferences , decreasing muscles stripping during osteotomy ,decrease condylar torque and so securing preoperative condylar position during BSSO in comparison with using high medial cut BSSO.

NCT ID: NCT05708053 Active, not recruiting - Clinical trials for Ischemic Reperfusion Injury

Cardio-protective Effect of Metformin in Patients Undergoing PCI

Start date: December 9, 2019
Phase: Phase 3
Study type: Interventional

This is a two-arm randomized parallel study. Patients who will be meeting the above-mentioned criteria and agree to take part in the study, were asked to sign an informed consent prior conducting the study. The whole study protocol were presented to the local institutional review board (IRB).

NCT ID: NCT05707169 Active, not recruiting - Venous Leg Ulcer Clinical Trials

Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose Vein

Start date: January 4, 2023
Phase: N/A
Study type: Interventional

EVLA is used in in treating refluxing veins, commonly the GSV. The tip of catheter is usually placed 2-2.5 cm distal to the sapheno-femoral junction. This technique theoretically provides the lowest risk for endothermal heat-induced thrombosis (EHIT). In the present study we aimed to evaluate the zero-distance technique (the kissing technique) compared to 2-cm distance from SFJ valve in ablating incompetent GSV.

NCT ID: NCT05704088 Active, not recruiting - Lupus Nephritis Clinical Trials

SGLT2 Inhibitors Between Reno Protective Effects and Impact on Bone and Mineral Disease Among Lupus Nephritis Patients

Start date: October 8, 2022
Phase: Phase 4
Study type: Interventional

The goal of this Randomized, controlled trial in 100 patients with LN with an estimated glomerular filtration rate (eGFR) of 25-75 ml/min/1.73m2. Diagnosis of LN was performed by renal biopsy, and all of the renal biopsies were carried out at urology and nephrology center. 1. The main questions it aims to answer are: - Assess the role of sodium glucose co transporter 2 inhibitors (SGLT2i) in regression of ongoing kidney and cardiac diseases among diabetic or non-diabetic patients with lupus nephritis (LN) under different immunosuppressive therapies. - Investigate the impact of SGLT2i on bone and mineral metabolism in these patients. Participants will be randomized into two groups : - Study group: will receive SGLT2i as add on drug or replace another drug according to the patient clinical situation, Dapagliflozin 10 mg will be used once daily with or without food. - Control group: will be maintained on their medication.