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Extracellular Vesicles and Dysregulated Coagulation in the Prediction of Stroke — PREDICT-EV  

Stroke, Ischemic Clinical Trial

Official title:
PREDICT-EV; the Association of Extracellular Vesicles and Dysregulated Coagulation in the Prediction of Stroke

Clinical Trial Summary

Annually 100,000 strokes occur, placing stroke as the largest cause of disability in the UK. 90% of strokes are preventable, leading to national focus on programmes including "The National Stroke Programme" to act on preventing, treating, and improving post-stroke care. Importantly, over 25% of ischaemic stroke sufferers have previously had a Transient Ischaemic Attack (TIA), which presents the biggest concern for TIA patients. There are no measures which reliably identify TIA patients most likely to suffer a stroke. Novel biomarkers for predicting stroke are key to addressing this problem. The PREDICT-EV study aims to screen 300 TIA patients and follow them over 12-months. The investigators will determine if a novel biomarker we've identified to increase thrombotic risk (endothelial derived extracellular vesicles) and the resulting increased prothrombin time is associated with patients at highest risk of stroke.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05645081
Study type Observational
Source Cwm Taf University Health Board (NHS)
Contact Jessica Williams, PhD
Phone 02920417077
Email jwilliams3@cardiffmet.ac.uk
Status Recruiting
Phase
Start date October 1, 2021
Completion date September 1, 2027
View Details
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