Stroke, Ischemic Clinical Trial
Official title:
Moderate-intensity Rosuvastatin Plus Ezetimibe Versus High-intensity Rosuvastatin for Target LDL-C Goal Achievement in Patients With Recent Ischemic Stroke: a Randomized Clinical Trial
A randomized clinical trial for the comparison of the efficacy and safety of moderate-intensity rosuvastatin plus ezetimibe versus high-intensity rosuvastatin for target LDL-C goal achievement in patients with recent ischemic stroke
The purpose of this study is to compare the efficiency and safety on the target LDL-C goal
achievement between rosuvastatin 10 mg plus ezetimibe 10 mg (rosuvastatin/ezetimibe 10/10 mg)
once daily versus rosuvastatin 20 mg once daily in patients with recent ischemic stroke.
The target LDL-C goal achievement rate in patients with recent ischemic stroke has not been
well studied. In particular, no clinical studies have been conducted comparing the efficacy
and safety of low-dose rosuvastatin plus ezetimibe with high-dose rosuvastatin single agent
for achieving target LDL-C levels.
In this trial, the investigators aim to compare the efficacy of the target LDL-C achievement
between rosuvastatin 10 mg plus ezetimibe 10 mg (rosuvastatin/ezetimibe 10/10 mg) and
rosuvastatin 20 mg in patients with recent ischemic stroke.
For this trial, more than 292 patients (584 total) per group will be enrolled.
Subjects who were satisfied with the inclusion/exclusion criteria of this trial and who
agreed to participate in the clinical trial in writing were randomly assigned to a 1:1 ratio
in the experimental group (the low-dose combination of rosuvastatin plus ezetimibe) and
comparator group (high-dose rosuvastatin).
The duration of administration of the drug for clinical trials is 90 days (±14 days), and the
efficacy and safety evaluation parameters are compared with baseline.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04069767 -
Innovative Physiotherapy in Stroke Rehabilitation
|
N/A | |
| Recruiting |
NCT06342206 -
The Assessment of Acute /Chronic Phase in Patients With Ischemic Cerebral Stroke Using TCM Diagnostic Tools
|
||
| Recruiting |
NCT03605381 -
MORbidity PRevalence Estimate In StrokE
|
||
| Enrolling by invitation |
NCT04956211 -
Periodontal Treatment and Ischemic Stroke
|
N/A | |
| Active, not recruiting |
NCT05098236 -
Effect of Visual Retraining on Visual Loss Following Visual Cortical Damage
|
N/A | |
| Completed |
NCT03942588 -
High-intensity Interval Training After Stroke
|
N/A | |
| Recruiting |
NCT04949334 -
Effects of Respiratory Muscle Training in Patients With Acute Ischemic Stroke
|
N/A | |
| Terminated |
NCT04095767 -
Assessing Safety and Performance of the ANA Catheter System, Combined With a Stent Retriever in Acute Ischemic Stroke
|
N/A | |
| Not yet recruiting |
NCT06352086 -
Understanding Visual Processing After Occipital Stroke
|
||
| Withdrawn |
NCT04991038 -
Clinical Investigation to Compare Safety and Efficacy of DAISE and Stent Retrievers for Thrombectomy In Acute Ischemic Stroke Patients
|
N/A | |
| Completed |
NCT01937182 -
The Efficacy of Citalopram Treatment in Acute Stroke
|
Phase 2 | |
| Completed |
NCT03649295 -
Combined Conventional Speech Therapy and Functional Electrical Stimulation in Dysphagia Following Stroke
|
N/A | |
| Recruiting |
NCT05303649 -
Effects of Neuronavigated Theta Burst Stimulation in Therapy of Post-stroke Aphasia
|
N/A | |
| Completed |
NCT04233515 -
Use of Oral Anticoagulants and Symptoms in Patients With Atrial Fibrillation in Örebro County
|
||
| Completed |
NCT05102877 -
Sensory Versus Motor Level Neuromuscular Electrical Stimulation
|
N/A | |
| Completed |
NCT04089917 -
A Study of the Use of the Q Aspiration Catheter to Remove Clot in Stroke Patients
|
||
| Completed |
NCT05221112 -
Effects of PNF Patterns Training on Trunk Balance, and Gait in Chronic Stroke Patients
|
N/A | |
| Not yet recruiting |
NCT05035953 -
Thrombolysis Combined With Edaravone Dexborneol on Hemorrhagic Transformation for Acute Ischemic Stroke
|
Phase 2 | |
| Not yet recruiting |
NCT05210088 -
PLAsticity, Security and Tolerance to Intermittent Hypoxic Conditioning Following Stroke
|
Phase 1/Phase 2 | |
| Completed |
NCT06326801 -
Resistive Diaphragmatic Breathing Exercise With Pursed Lips Breathing Exercise in Sub-acute Stroke Patients
|
N/A |