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Chronic Pain clinical trials

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NCT ID: NCT05722587 Completed - Pain, Chronic Clinical Trials

Students' Understanding and Beliefs About Pain Before and After a One-day Pain Science Education Conference: an Intervention

Start date: March 2, 2023
Phase: N/A
Study type: Interventional

The beliefs held by students lead to behaviours in response to their pain which can be both helpful or a hindrance to how they manage their pain. The one-day education event aims to educate the cohort on the contemporary scientific understanding of persistent pain using a mixture of methods. It is hoped this event will result in an improvement in the alignment of beliefs and behaviours to contemporary understanding of persistent pain. The principal aim is to evaluate the pre-post knowledge and beliefs about pain following a one-day pain education event in year 12 students, aged 16 or above.

NCT ID: NCT05714254 Completed - Chronic Pain Clinical Trials

Multiple Dose Study of Safety and Pharmacokinetics of MEDI0618 in Healthy Volunteers

Start date: December 12, 2022
Phase: Phase 1
Study type: Interventional

This is a single centre, randomised, double-blind, placebo-controlled, multiple ascending dose study of MEDI0618 in healthy male and female volunteers. Subjects will receive MEDI0618 or placebo administered by intravenous infusion or subcutaneous injection. Safety, tolerability and pharmacokinetics of multiple ascending doses of MEDI0618 will be assessed.

NCT ID: NCT05713786 Completed - Chronic Pain Clinical Trials

Physical Exercise, Motor Activity and Post-mastectomy Pain Syndrome.

Start date: September 1, 2021
Phase:
Study type: Observational

Pain is an unpleasant sensation common to all those who undergo surgery. Several studies indicate that 40-60% of patients experience the post-operative experience and can be caused by both internal and external stimuli. The most patients define the post-operative experience as a very painful condition that interferes with normal daily activities. Chronic post mastectomy pain is a condition characterized by pain in the anterior chest, armpit, and/or upper arm, usually ipsilateral to surgery, which begins after mastectomy or quadrantectomy and persists for longer. three months after surgery. It can become chronic in a broad spectrum of conditions. In fact, it is estimated that between 10 and 50% of elective interventions can generate persistent post-surgical pain. Aim of this prospective observational study is to evaluate the effects of motor and/or sports activity on the intensity and interference of chronic pain in quality of life of women underwent mastectomy.

NCT ID: NCT05713500 Completed - Parkinson Disease Clinical Trials

Comparative Study of Personality in Parkinson's Disease Patients With Other Chronic Pain

PSYCHO-PAIN
Start date: February 16, 2023
Phase:
Study type: Observational

The present study compare personality of Parkinson's Disease (PD) patients with chronic, PD patients without pain and non-parkinsonian patients with other chronic pain condition.

NCT ID: NCT05707546 Completed - Chronic Pain Clinical Trials

Knowledge, Beliefs and Attitudes of Greek Physiotherapists About Communication With Chronic Musculoskeletal Patients

Start date: January 28, 2023
Phase:
Study type: Observational

The purpose of current research study is to assess physiotherapists's knowledge, beliefs and attitudes about empathy, motivational interviewing and shared decision making in chronic musculoskeletal patients. An e-survey study will be conducted based on Checklist for Reporting Results of 52 Internet E-Surveys (CHERRIES)

NCT ID: NCT05698069 Completed - Chronic Pain Clinical Trials

Turkish Version of Pain Modulation Index

Start date: February 1, 2022
Phase:
Study type: Observational

In order to assess the validity and reliability of the Turkish version of Pain Modulation Index, 125 volunteers with chronic pain were enrolled in the study. Test and re-test method was used to assess reliability and correlation analyses with Pain Detect, visual analog scale pain and central sensitization inventory scores were used to assess validity of the questionnaire. Turkish version of the Pain Modulation Index was found to be a valid and reliable tool for evaluating chronic pain.

NCT ID: NCT05695209 Completed - Depression Clinical Trials

Equity Using Interventions for Pain and Depression - Pilot Study

EQUIPD-Pilot
Start date: June 22, 2023
Phase: N/A
Study type: Interventional

This project is part of the NIH Helping to End Addiction Long-term (HEAL) initiative (https://heal.nih.gov/). This pilot randomized controlled trial (RCT) is part of phase 1 of a two-phase, 5-year project with the overarching goal of testing a decision aid (DA)/coaching intervention, tailored to Black patients with comorbid chronic pain and depression, to encourage use of and adherence to nonpharmacological pain treatments (NPTs). This 2-arm pilot trial will aim to enroll up to 40 Black patients with comorbid chronic musculoskeletal pain and depression in primary care from an urban safety-net health system with the end goal of at least 30 patients completing the trial. After the baseline assessment, patients randomized to the intervention will be asked to participate in 4 coaching sessions over approximately 12 weeks. Sessions will use Motivational Interviewing principles to foster openness to NPTs and self-efficacy by helping patients identify their goals and priorities, understand their NPT options, prepare them to discuss and choose options with their primary care providers (PCPs), and reinforce these choices to foster maintenance of these changes. DA contents will be integrated into these sessions, which will facilitate discussion of these options with their PCP. The first 3 sessions take place prior to the patient's next scheduled PCP visit; the final session occurs after this visit. Assessments will be conducted at baseline, 3 months (i.e., after completing the final coaching session), and 6 months. Patients randomized to the wait-list control group will receive usual care (in addition to study assessments at baseline, 3 months, and 6 months). After completing the final assessment, they will then be given the DA along with a 20-minute coaching session to walk them through it (patients may decline the coaching session or schedule for a future time).

NCT ID: NCT05672394 Completed - Lung Cancer Clinical Trials

US-Guided Serratus Anterior Plane Block Versus Thoracic Epidural in Patients Undergoing Thoracotomy

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

Thoracic surgeries is known to be one of the most painful surgeries . Multiple analgesic techniques have been used for post operative analgesia including Thoracic epidural , Patient Controlled Analgesia and systemic opioids. Opioids are associated with multiple sied effects including : PONV , Respiratory depression and ileus while thoracic epidural has its own complications such as hemodynamic instability , injury of spinal cord, pneumothorax and epidural hematoma. Peripheral nerve blocks provide good alternative for perioperative analgesia. The purpose of our study is to compare the effectiveness of perioperative continuous serratus anterior plane block versus continuous thoracic epidural in pain management during thoracic surgeries for malignancy resection.

NCT ID: NCT05659836 Completed - Chronic Pain Clinical Trials

Spinal Cord Stimulation Trial to Permanent Prediction

SCS T2P
Start date: May 27, 2021
Phase:
Study type: Observational

Spinal Cord Stimulation Trial to Permanent Prediction is a prospective, longitudinal, multi-center, non-randomized, multi-arm, open-label, clinical feasibility study designed to investigate whether objective data collected from chronic pain patients is predictive of subjective patient-reported outcomes and of adjustments to patient programming parameters.

NCT ID: NCT05647031 Completed - Chronic Pain Clinical Trials

Pain in Competitive Athletes With Physical Disabilities and Techniques for Its Management

Start date: December 18, 2020
Phase:
Study type: Observational

There are psychosocial factors that affect pain, and therefore, psychological intervention techniques have been added to its usual pharmacological and physiotherapeutic treatment. Despite the abundant evidence that addresses psychosocial factors as clear mediators in the perception of pain, the use of psychological techniques for pain management in competitive athletes, and more especially in competitive athletes with physical disabilities, is scarce. The purpose of this study was to ascertain the perception of high-level competitive athletes with physical disability and sports agents (coaches, physiotherapists and psychologists).