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Cardiovascular Disease clinical trials

View clinical trials related to Cardiovascular Disease.

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NCT ID: NCT02898467 Not yet recruiting - Diabetes Clinical Trials

Atherothrombosis Markers in Diabetics

MADI
Start date: October 2016
Phase: N/A
Study type: Observational

Intraplaque hemorrhage is the driving force of atherothrombotic plaque vulnerability to rupture and associated clinical complications. Polymorphonuclear neutrophils (PMNs) represent about 70% of leukocytes and may constitute a source of proteases and oxidants that favour plaque rupture. Our objective is to evaluate PMN activation in atherosclerotic plaque of non-diabetic versus type 2 diabetic patients. For this purpose, investigators will quantify the presence of cell-free DNA, that reflect the formation of neutrophil extracellular traps (NETs) in carotid endarterectomy samples.

NCT ID: NCT02720809 Not yet recruiting - Clinical trials for Cardiovascular Disease

Health2016: Monitoring Chronic Disease and Risk Factors in the General Population

Start date: May 2016
Phase: N/A
Study type: Observational

Health2016 is a general population cross-sectional study aimed at completing af monitoring program for monitoring chronic disease and risk factors in the period 2006 to 2016. Similar studies have been performed in 2006, 2010, and 2013.

NCT ID: NCT02677467 Not yet recruiting - Clinical trials for Cardiovascular Disease

Correlation Between Epistaxis and Cardiovascular Disease

CBECD
Start date: March 2016
Phase: N/A
Study type: Observational [Patient Registry]

Investigators examine blood-pressure variance, several cardiovascular risk factors of patient with epistaxis. As a result of collected data, investigators look into correlation between epistaxis and hypertensive cardiovascular disorder.

NCT ID: NCT02578355 Not yet recruiting - Clinical trials for Coronary Artery Disease

National Plaque Registry and Database

OPeRA
Start date: September 2016
Phase: N/A
Study type: Observational [Patient Registry]

The ultimate goal of this project is to develop a risk score to identify patients with vulnerable coronary atherosclerotic plaques, who are prone to suffer acute coronary syndrome. Early identification of vulnerable plaques may have an enormous impact on public health through primary and secondary prevention of acute myocardial infarction. Investigators hypothesize that a risk score that incorporates non-invasive coronary CT imaging (calcium score and/or coronary CTA) in combination with clinical characteristics (classical risk prediction models) will improve the identification of patients who are at highest risk to suffer myocardial infarction or sudden cardiac death. The overall goal of the OPeRA project is to develop, implement and validate a novel risk assessment tool based on image markers and clinical characteristics to identify patients who are at increased risk to suffer myocardial infarction or sudden cardiac death.

NCT ID: NCT02315313 Not yet recruiting - Clinical trials for Cardiovascular Disease

The Link Between the Clinical Resting Heart Rate and Sympathetic Overactivation

Start date: December 2014
Phase: N/A
Study type: Observational

It is a retrospective study with no products limitation to investigate the link between clinical resting HR and SOA. Use HR≤60bpm as control group, compare other three groups with the control group and find out the correlation between HR and SOA indexes.

NCT ID: NCT02012140 Not yet recruiting - Clinical trials for Coronary Artery Disease

Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Stable Angina, NSTEMI and STEMI Undergoing PCI

Start date: January 2014
Phase: Phase 4
Study type: Interventional

Ticagrelor therapy has been shown to reduce the rates of cardiovascular events and all-cause mortality compared to clopidogrel therapy in patients with acute coronary syndromes (ACS). The benefit of this study would be to demonstrate that ticagrelor therapy is associated with equivalent platelet inhibition irrespective of the disease status in patients undergoing PCI.

NCT ID: NCT01816399 Not yet recruiting - Clinical trials for Cardiovascular Disease

New Vectorcardiogram Analysis a Good Predictor of Coronary Disease in Patients With Normal Rest 12-leads ECG

Start date: April 2013
Phase: N/A
Study type: Observational

The aim of this study is to determine whether a new vectorcardiogram (VCG) analysis will facilitate the detection of significant coronary disease (CAD) in patients with normal rest 12-leads ECG (NE).

NCT ID: NCT01816347 Not yet recruiting - Clinical trials for Cardiovascular Disease

Evaluation of Pre-deployment Device-to-artery Relative Axial Motion in Coronary Catheterizations

Start date: April 2013
Phase: N/A
Study type: Observational

The cyclic movement of the heart and the coronary arteries induces relative axial movement between the artery and a pre-deployed intra-luminal stent which may cause malpositioning. Using a new imaging algorithm to indicate the position of a stent in patients undergoing percutaneous coronary intervention (PCI), the investigators will measure the pre-deployment relative, intra-luminal stent axial movement in the different coronary arteries to facilitate the precise deployment site.

NCT ID: NCT01329159 Not yet recruiting - Clinical trials for Cardiovascular Disease

Cardio-Respiratory Health and Indoor Pollution

Start date: April 2011
Phase: N/A
Study type: Observational

The aim of this study is to assess in the sample of population resident in the KHUMBU valley (NEPAL): 1. the respiratory function decline by means of spirometry and the respiratory health by means of questionnaire and six-minute walking distance 2. the presence of markers of early atherosclerosis with ultrasound and to estimate the value of systolic pulmonary pressure in comparison with not exposed subjects. The investigators hypothesize that the chronic exposure to indoor pollution 1. can accelerate the physiological respiratory function decline, usually around 15-20mL/year in healthy subjects 2. induce cardiovascular impairment The population of high altitude villages is a unique sample to study the effect of the only indoor pollution. In fact, the absence of traffic, due to the lack of roads, and the very low level of smoking habits allow to have no other confounding factors 3. to study and analyze how the architectural features of the buildings of the village (distribution of domestic locals, natural or non natural ventilation systems, domestic activities, materials used, etc.) affect the indoor pollution from carbon monoxide, which necessarily is developed indoor during the daily life activities. What the project prospects is to gather information focused on the scale of the building, independently from the typology, to study a model that will help to describe which aspects are most important to what concern the genesis of the pollution of the indoor air.

NCT ID: NCT01054040 Not yet recruiting - Clinical trials for Cardiovascular Disease

The Impact of Portion Plates for Weight Loss on Cardiac Rehabilitation Patients

Start date: February 2010
Phase: N/A
Study type: Interventional

The study will involve cardiac rehabilitation clients and will measure their weight, height, waist circumference and blood pressure comparisons between first and final visit (after 8 weeks). A control group will receive usual care and an experimental group will receive usual care plus a portion control plate for their meals. Patients currently have their waist circumference, weight, height and blood pressure measured at their first visit (week 0) and at their final visit (week 8). This study would compare these three parameters at these same times (week 0 and week 8) between the control and experimental groups. The control group would receive the usual care while the experimental group would receive usual care plus be given a portion control plate at week 0. The hypothesis of this study is that subjects from the experimental group will have an average reduction in: (a) waist circumference by > 5%, (b) weight or BMI by > 5%, and (c) systolic and diastolic blood pressure by >10%. The subjects in the control group are hypothesized to show an average less than these targets for the experimental group.