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Diabetes Mellitus, Type 2 clinical trials

View clinical trials related to Diabetes Mellitus, Type 2.

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NCT ID: NCT05441267 Not yet recruiting - Clinical trials for Diabetes Mellitus, Type 2

A Study of Cardiovascular Events iN Diabetes Plus

ASCEND PLUS
Start date: September 2022
Phase: Phase 4
Study type: Interventional

ASCEND PLUS is testing whether, for people with type 2 diabetes who have not previously had a heart attack or stroke, regularly taking a tablet called semaglutide can safely help to reduce heart attacks, strokes, mini-strokes, the need for any procedures to unblock or bypass an artery to their heart, and the chance of dying because of vascular problems.

NCT ID: NCT05440968 Not yet recruiting - Clinical trials for Diabetes Mellitus, Type 2

Comparative Effectiveness of POC-A1c vs the Current Standard Based on OGTT for Early Detection DM2 in Colombia

EDDIT-1
Start date: June 30, 2022
Phase: N/A
Study type: Interventional

Evaluate the impact of conducting a screening questionnaire (FINDRISC) and the implementation of a point-of-care HBA1c test for those with identified risk to suffer Diabetes in ten years, to improve the proportion of patients attending for a confirmatory test ( oral glucose tolerance test ) and evaluate the impact of such a strategy to minimize type 2 diabetes outcomes.

NCT ID: NCT05440591 Recruiting - Diabetes Clinical Trials

Effects of Dapagliflozin and Metformin on Vascular Function in Newly-Diagnosed Treatment-Naive Type 2 Diabetes

DMVascular
Start date: April 1, 2019
Phase: Phase 4
Study type: Interventional

Trial Design: This is a 12 week randomised controlled open label trial comparing the impact of Dapagliflozin, Metformin and combination therapy on vascular function in newly diagnosed T2DM patients.

NCT ID: NCT05437913 Active, not recruiting - Diabetes type1 Clinical Trials

Protocol for Self-Compassion Intervention for Teens With Diabetes Type 1 and Their Caregivers

SWEET
Start date: September 6, 2021
Phase: N/A
Study type: Interventional

The goal of this study is to examine the feasibility and potential effectiveness of a short (4 sessions) self-compassion intervention for adolescents with T1D and their caregivers on psychological, metabolic, and behavioral outcomes.

NCT ID: NCT05437848 Recruiting - Diabetes Clinical Trials

Chinese Multiple Dose Escalation (MDE) High Dose Study

COTA China PK
Start date: February 25, 2022
Phase: Phase 1
Study type: Interventional

A Phase 1 Randomized, Double-blinded, Placebo-controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of Cotadutide in Overweight/Obese Subjects with Chinese ancestry with Type 2 Diabetes Mellitus

NCT ID: NCT05435677 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

A Research Study to Look at How Insulin Icodec and Semaglutide Work in the Body of People From China With Type 2 Diabetes When Given Alone or Together

Start date: June 22, 2022
Phase: Phase 1
Study type: Interventional

This study will look at a new medicine, called IcoSema, for treatment of type 2 diabetes. IcoSema is a combination of a new insulin, called insulin icodec, and a GLP-1 receptor analogue, called semaglutide. Insulin icodec is a possible new medicine. That means that the medicine has not yet been approved by the authorities. Semaglutide is a medicine already approved by the authorities in the EU, USA, China and Japan. The study will look at the way insulin icodec and semaglutide reach and stay in participants blood after injection when given together as IcoSema or alone as insulin icodec and semaglutide. Participants will get each of the 3 medicines (IcoSema, insulin icodec and semaglutide) at 3 different timepoints: The order in which participants get them is decided by chance. Participants will get the 3 medicines as an injection under the skin in the thigh. The injections will be done by study staff. The time between injections is 6 to 9 weeks. The study will last for about 19 to 26 weeks. Participants will have 31 or 32 visits to the clinic. 3 of the visits will be in-house visits, meaning that participants will stay at the clinic for 5 or 6 days (4 or 5 nights). Women cannot take part if pregnant, breast-feeding or plan to get pregnant during the study period.

NCT ID: NCT05435157 Recruiting - Diabetes Mellitus Clinical Trials

Residual Gastric Volume Measured by Ultrasound in Diabetic Surgical Population Versus Non-diabetic Surgical Population.

Start date: March 9, 2022
Phase:
Study type: Observational

Comparison of residual gastric volume measure by ultrasounds between diabetic and non-diabetic patients scheduled for elective surgery

NCT ID: NCT05434754 Not yet recruiting - Clinical trials for Diabetes Mellitus, Type 1

Keeping in Touch (KiT) With Youth as They Transition to Adult Type 1 Diabetes Care

KiT
Start date: September 2022
Phase: N/A
Study type: Interventional

We are testing the effectiveness of an eHealth digital tool co-designed with patients and providers to improve diabetes self-efficacy in young adults as they transition to adult type 1 diabetes care.

NCT ID: NCT05431296 Not yet recruiting - Type 2 Diabetes Clinical Trials

Glucose Control Using Continuous Glucose Monitoring in People With Type 2 Diabetes Who Have Had Acute Myocardial Infarct

GLAM
Start date: July 2022
Phase: N/A
Study type: Interventional

Glucose monitoring after Acute Myocardial infarct in people with diabetes is a Dexcom funded feasibility study that is investigating whether the use of continuous glucose monitors (Dexcom G6 model) in people with type 2 diabetes facilitates time in glycaemic range in the 6 months after an acute myocardial infarction. As a secondary outcome it will investigate whether time in glycaemic range is associated with changes in mortality and major adverse cardiac events in the 6 months after acute myocardial infarct.

NCT ID: NCT05430139 Not yet recruiting - Diabetes Clinical Trials

Dried Blood Spot Testing for At Home Health

Start date: June 27, 2022
Phase:
Study type: Observational

DBS (Dried blood spot) is the collection of a small volume of blood on paper cards and subsequent transport to an analytical laboratory. This method is widely used for newborn screening programs around the world to identify inborn errors of metabolism where early diagnosis and treatment can be lifesaving. The World Health Organization and World Anti-Doping Agency (WADA) have independently endorsed DBS as an alternative to conventional testing methods due to its lessened invasiveness, lower collection and transport cost, reduction in sample storage needs, and for some analytes, improved sample stability. There are hundreds of publications describing DBS testing and some commercial ventures offering direct-to-consumer testing using DBS. However, it is not clear if there have been concerted efforts to develop DBS sampling for adults for home collection in concert with high quality, accredited central clinical laboratories. The proposal herein is focused on developing and validating DBS for at home and remote sample collections for routine diagnostic testing.