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Breast Cancer clinical trials

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NCT ID: NCT05704855 Not yet recruiting - Breast Cancer Clinical Trials

A Combined Exercise Training Program for Women Living With Breast Cancer

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

Women living with and beyond breast cancer are at a heightened risk for experiencing adverse mental health outcomes and declines in cognitive function following chemotherapy treatment. Women living with and beyond breast cancer have reported increased levels of anxiety and depression during the COVID-19 pandemic which may have significantly impacted their quality of life (QoL). Physical activity (PA) may be used to manage mental health and improve cognitive function in women living with and beyond breast cancer. Research is needed to assess the feasibility of a supervised, remotely delivered, combined (i.e., aerobic + resistance) exercise program to improve cognitive function and manage adverse mental health in women living with and beyond breast cancer. This study will pilot an 8-week, remotely delivered, combined (i.e., aerobic + resistance) exercise and behavioural counselling intervention on cognitive function and mental health outcomes (i.e.,anxiety, depression, self-efficacy and self esteem) in women living with breast cancer who received chemotherapy treatment within 12-48 months.

NCT ID: NCT05704283 Not yet recruiting - Breast Carcinoma Clinical Trials

3D Ultrasound for the Imaging of Axillary Lymph Nodes in Patients With Breast Cancer

Start date: March 1, 2023
Phase: Early Phase 1
Study type: Interventional

This early phase I studies how well a new 3D ultrasound (3D-US) imaging technology works in evaluating axillary lymph nodes in patients with breast cancer. Ultrasound uses high-frequency sound waves to generate images of the body.

NCT ID: NCT05703399 Not yet recruiting - Breast Carcinoma Clinical Trials

Long Term Followup of Patients Enrolled in MC1137, BEAUTY Study

Start date: January 27, 2023
Phase:
Study type: Observational

This study gathers information and samples for further analysis as part of the BEAUTY study. The purpose of the BEAUTY study was to better understand the reasons why or why not breast cancers respond to standard chemotherapy. Collecting samples of blood and tissue and health and treatment information from patients on the BEAUTY study may help doctors identify changes that make cancer better respond to standard chemotherapy and develop better therapies for the treatment of cancer.

NCT ID: NCT05703269 Not yet recruiting - Clinical trials for Non-small Cell Lung Cancer

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy

HYPOGRYPHE
Start date: February 15, 2023
Phase: Phase 3
Study type: Interventional

This study is designed to see if we can lower the chance of side effects from radiation in patients with breast, kidney, non-small cell lung cancer or melanoma that has spread to the brain and who are also being treated with immunotherapy, specifically immune checkpoint inhibitor (ICI) therapy. This study will compare the usual care treatment of single fraction stereotactic radiosurgery (SSRS) given on one day versus fractionated stereotactic radiosurgery (FSRS), which is a lower dose of radiation given over a few days to determine if FSRS is better or worse at reducing side effects than usual care treatment.

NCT ID: NCT05700669 Not yet recruiting - Breast Cancer Clinical Trials

Study To Assess Safety And Efficacy Of AsiDNA In Combination With Olaparib In Participants With Recurrent Solid Tumors

Start date: February 20, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase 1b/2 open-label, multicenter, basket study to determine the safety, anti-tumor activity, tolerability, and pharmacokinetics /pharmacodynamics of AsiDNA in combination with olaparib in participants with recurrent epithelial ovarian cancer, breast cancer and metastatic castration-resistant prostate cancer who have progressed on previous Poly (ADP-ribose) polymerase (PARP) inhibitor therapy. The study will be conducted in two phases. The Phase 1b dose escalation study designed to establish the safety, tolerability, pharmacologically active doses/ maximum tolerated dose and/or recommended phase 2 dose of AsiDNA in combination with olaparib.

NCT ID: NCT05700396 Not yet recruiting - Breast Cancer Clinical Trials

Breast Cancer Survivor Educational Intervention

Start date: March 2023
Phase: N/A
Study type: Interventional

The goal of this study is to test a 6-week virtual education program among Black breast cancer survivors. The virtual program includes sessions on physical activity, goal setting, nutrition, sleep, stress, and social connections.

NCT ID: NCT05700019 Not yet recruiting - Breast Cancer Clinical Trials

Effects of 'Pinkwashed' Alcohol Ads in an Online RCT

Start date: January 2023
Phase: N/A
Study type: Interventional

The primary objective of this study is to examine how exposure to "pinkwashed" alcohol advertisements (i.e., ads that associate the company with breast cancer awareness or charities) affects consumers' perceptions that alcohol increases the risk of breast cancer. The investigators will randomize participants to view 3 'pinkwashed' social media advertisements for alcohol or 3 control advertisements for alcohol (i.e., 'de-pinked' standard alcohol advertisements that match the intervention advertisements on overall design but do not mention breast cancer). Each participant will view the 3 advertisements for their arm (presented in random order) and respond to survey questions programmed in Qualtrics.

NCT ID: NCT05699902 Not yet recruiting - Pain, Postoperative Clinical Trials

Pectoral Nerve Block During Mastectomy

PNB
Start date: April 1, 2023
Phase: N/A
Study type: Interventional

Impact of pectoral nerve block on postoperative pain and quality of recovery in patients undergoing breast cancer surgery: A prospective study

NCT ID: NCT05699577 Not yet recruiting - Clinical trials for Breast Cancer Female

Prognostic Value of Some Biochemical Markers in Breast Cancer

Start date: February 2023
Phase:
Study type: Observational

breast cancer is the most common type of cancer in women and first cause of cancer death among them. in Egypt it constitutes 33% of female cancer cases and more than22000 new cases diagnosed each year. there are many prognostic factors for breast cancer as Tumer size, axillary lymph node status, hormonal receptor status, and tumer markers as Ca15-3 and interferon gamma.

NCT ID: NCT05695313 Not yet recruiting - Breast Cancer Clinical Trials

Randomized Study Versus Placebo for the Prevention of Neurotoxicity Induced by Weekly PACLITAXEL

NEUROTAX
Start date: April 1, 2023
Phase: Phase 2
Study type: Interventional

This study recommends the use of OnLife dietary supplement, which will be followed by a few day before the initiation of PACLITAXEL, for the prevention of PACLITAXEL induced neuropathy. OnLife will be continued one month after stopping chemotherapy. This would limit the number of PACLITAXEL dose reductions and premature interruptions of this chemotherapy, thus potentially improving the results in terms of antitumor efficacy, while improving the quality of life of patients treated with weekly PACLITAXEL.