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Breast Cancer clinical trials

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NCT ID: NCT05392985 Active, not recruiting - Breast Cancer Clinical Trials

Detection and Analysis of MBC With Heterogeneous ER Expression

Start date: January 15, 2022
Phase:
Study type: Observational

To investigate the treatment pattern and efficacy of MBC patients with ER heterogeneity using a novel convenient way of 18F-fluoroestradiol positron emission tomography/computed tomography (18F-FES PET/CT).

NCT ID: NCT05245162 Active, not recruiting - Clinical trials for Breast Cancer Female

Fertility Changes Due to Cancer: an Investigation of Meaning, Psychological Distress, and Psychologi

Start date: January 11, 2021
Phase:
Study type: Observational

Establish the relationship between meaning and psychological distress in young women with breast cancer who experienced reproductive concerns due to cancer diagnosis and treatment and their partners.

NCT ID: NCT05224310 Active, not recruiting - Breast Cancer Clinical Trials

Comparing the Quality of Analgesia With Pectoral Nerve Block and Serratus Plane Block in Modified Radical Mastectomy

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The use of pectoral nerve block (PECSB) is a new technique during modified radical mastectomy MRM. The Serratus anterior Plane (SAP) Block has been proven to be an effective component of multimodal analgesia regimens for a variety of thoracic procedures including MRM. In this study, the investigators will assess and compare the quality of analgesia with ultrasound-guided Serratus plane block and pectoral nerve block in patients undergoing modified radical mastectomy MRM.

NCT ID: NCT05222100 Active, not recruiting - Breast Cancer Clinical Trials

Effect of Breast Implants om Mammography Screening

Start date: May 12, 2021
Phase:
Study type: Observational [Patient Registry]

The purpose of the study is to survey how many women have breast implants in the mammography screening population and the effect of implants on the number and type of examinations and on costs.

NCT ID: NCT05170087 Active, not recruiting - Breast Cancer Clinical Trials

Radiomic Analysis for Predicting Treatment Response and Clinical Outcomes in Malignancies

Start date: March 2, 2020
Phase:
Study type: Observational

In this study, the investigators aim to undertake a retrospective analysis of CT and MRI scans for patients undergoing radiation treatment to develop radiomic signatures to predict treatment response and clinical outcomes.

NCT ID: NCT05160324 Active, not recruiting - Breast Cancer Clinical Trials

T1-T2 Breast Cancer: Comparison Between Removal and Preservation of Axillary Lymph Nodes (SINODAR ONE)

SINODAR ONE
Start date: April 14, 2015
Phase: N/A
Study type: Interventional

Italian Multicentric non inferiority two-arm randomized clinical trial to verify that the experimental treatment (omission of axillary lymph node intervention) in the presence of sentinel lymph node metastases does not lead to a significant worsening in survival or in the risk of locoregional recurrence compared to standard treatment (removal of I-II level of axillary lymph nodes).

NCT ID: NCT05137067 Active, not recruiting - Breast Cancer Clinical Trials

A Novel Approach for Alleviating the Side Effects of Chemotherapeutic Agents.

Start date: January 20, 2021
Phase: Phase 2
Study type: Interventional

This study will assess the effectiveness of a natural nutraceutical in treating the known side effects of chemotherapeutic agents in cancer patients.

NCT ID: NCT05133674 Active, not recruiting - Breast Cancer Clinical Trials

Therapeutic Dose Monitoring (TDM) of Tamoxifen

Start date: April 4, 2022
Phase: Phase 2
Study type: Interventional

Tamoxifen is a potent and effective drug reducing the risk of dying from breast cancer in the adjuvant setting. Although more modern drugs have partly replaced tamoxifen, it is helpful in the neoadjuvant and metastatic settings as a single drug. Despite that, in the adjuvant setting, it is a valuable drug. This study aims to validate and study the feasibility of serial assessments, including therapeutic drug monitoring of tamoxifen, 4-hydroxytamoxifen and Z-endoxifen by capillary blood sampling, combined with patient-reported symptom scores. This will provide preliminary data to allow us to develop a future multicentre randomised clinical trial of personalised dose monitoring and adjustment of adjuvant tamoxifen therapy to enhance the quality of life and breast cancer outcomes.

NCT ID: NCT05118568 Active, not recruiting - Breast Cancer Clinical Trials

Assessment of Lumpectomy Margins With the Histolog Scanner in Comparison With Intraoperative Imaging Techniques

Polarhis
Start date: October 1, 2020
Phase:
Study type: Observational

Study to assess the capability of using the Histolog Scanner, a recent large field-of-view confocal laser scanning medical imaging device for the breast cancer detection in fresh lumpectomy margins.

NCT ID: NCT05062538 Active, not recruiting - Breast Cancer Clinical Trials

Cancer Patient Perspectives During COVID-19

Start date: August 24, 2020
Phase:
Study type: Observational

A web-based survey will be emailed to all adult women diagnosed with invasive breast cancer or ductal carcinoma in situ who have been seen as surgical consultations within the last year (06/01/19-06/01/20).