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Weight Loss clinical trials

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NCT ID: NCT03322514 Completed - Appetite Regulation Clinical Trials

Colonic Propionate, Appetite, and Weight Loss

ProAp
Start date: March 29, 2017
Phase: N/A
Study type: Interventional

The current protocol aims to investigate the impact of the propionate ester in conjugation with restricted diet on appetite and weight loss.

NCT ID: NCT03319862 Completed - Gynecomastia Clinical Trials

Post-massive Weight Loss Chest Contouring: Inferior Pedicle Technique in Pseudo-gynecomastia Correction

Start date: November 14, 2016
Phase: N/A
Study type: Observational

The massive weight loss leads an important excess of skin on thoracic level giving the aspect of a feminine breast with a relatively important ptose. Several techniques were described in the literature about gynaecomastia , but the post-bariatric pseudo-gynaecomastia was not handled yet enough. Moreover, there is no single consensual technique on this subject. The technique used in this service was described for the first time in 2008 ( 1 ) on a serie of 8 patients with an average follow-up of 13 months. Although the results are promising, no other publication was done, and the procedure remains badly represented in the world literature.

NCT ID: NCT03305237 Completed - Obesity Clinical Trials

The Meal Time Study

Start date: October 24, 2017
Phase: N/A
Study type: Interventional

This weight loss study will investigate the impact of calorie distribution across a day (large breakfast meals and smaller evening meals versus small breakfast meals and large evening meals) on body weight, and physiological and behavioral mechanisms regulating energy balance. Participants will undergo 2 x 4 week energy restriction protocols in a randomized cross over design; big breakfast (45% of calories in the morning meal, 20% at dinner) and big dinner (45% of calories in the evening meal, 20% at breakfast). We predict that timing of eating will influence energy balance, because morning energy expenditure is amplified in comparison to the evening. This study will allow us to assess whether the increased energy expenditure in the morning is linked to natural biological circadian rhythm or behavioral adaptions.

NCT ID: NCT03305172 Completed - Physical Activity Clinical Trials

Structuring Financial Incentives to Increase Physical Activity

Start date: October 9, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of different structures of long term financial incentives on increasing physical activity performed by subjects, as measured by the number of steps walked per day. Investigators are interested in studying whether physical activity increases during an intervention period (with incentives) and a post-intervention period (with no incentives).

NCT ID: NCT03304249 Completed - Weight Loss Clinical Trials

Rural Disparities in Pediatric Obesity: The iAmHealthy Intervention

Start date: October 13, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to learn if providing a family-based group program using mobile health technology (iAmHealthy Healthy Lifestyles Program) is effective at improving child weight, nutrition, and physical activity.

NCT ID: NCT03297307 Completed - Weight Loss Clinical Trials

Mother and Child Health Outcomes After Maternal Bariatric Surgery

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Childhood obesity has been a growing problem with more than 30% of children between 6 and 19 years old being considered overweight or obese. Obese children are at increased risk of developing diabetes, heart disease, metabolic syndrome, and are susceptible to the sociological effects of being overweight. Obesity is a multifactorial disease, is often familial and multi-generational, and studies have shown that parental obesity can increase the risk of a child becoming obese. Currently, one of the most successful treatment options for obesity is bariatric surgery. The Nebraska Medicine Bariatric Center offers patients counseling in improved dietary management, methods to increase physical activity, and psychological support. As part of the programs standard-of-care, each bariatric surgical patient receives consultation with a dietician, psychologist, and an exercise physiologist. We propose that mothers who are enrolled in the surgical weight loss program bring their children to attend the presurgical specialist consultation. Subjects enrolled in the study will have their height, weight, and physical activity assessed at preoperative and postoperative study visits. Study subjects will also complete questionnaires of their self-reported physical activity and eating habits at these study visits. The goal of this pilot study is to examine whether this behavioral intervention will have an impact on the overall health and weight of children whose mothers have received bariatric surgery.

NCT ID: NCT03287973 Completed - Clinical trials for Obstructive Sleep Apnea

Effect of Weight Loss and CPAP on OSA and Metabolic Profile Stratified by Craniofacial Phenotype

Start date: September 15, 2017
Phase: N/A
Study type: Interventional

Obstructive sleep apnea (OSA) is a common form of sleep-disordered breathing (SDB). Weight reduction has always been advocated in patients with OSA who are overweight and may lead to improvement in the severity of OSA. Previous study reported a randomized controlled trial of dietician-led lifestyle modification program (LMP) in 104 patients and found that LMP group had significantly more weight loss and reduced OSA severity, and the response was sustained after 8 months. This study is aimed to compare the effect of weight loss or CPAP alone on subclinical inflammation, insulin resistance and blood pressure in patients with obesity and moderate-to-severe obstructive sleep apnea, stratified according to the degree of craniofacial restriction. The study plans to recruit consecutive patients who have been referred to the Respiratory Clinic at the Prince of Wales Hospital with clinical suspicion of sleep-disordered breathing with specific study entry criteria including an age of 18 or more, body mass index (BMI) >25 kg/m2, and moderate to severe OSA diagnosed by home sleep study. Patients having conditions that will affect the serum level of hsCRP will be excluded.

NCT ID: NCT03287726 Completed - Obesity Clinical Trials

What is the Impact of Probiotics on Weight Loss Maintenance in Individuals With Obesity?

Start date: November 16, 2017
Phase: N/A
Study type: Interventional

Weight loss maintenance is the biggest challenge in obesity management, with the majority of weight-reduced individuals experiencing weight regain. The intake of probiotics has been shown to help in weight loss, but its potential in maximizing weight loss maintenance remains unknown. Therefore, the main aim of this study is to investigate the impact of probiotic consumption on weight loss maintenance. Secondary aims are to investigate if the intake of probiotics influences gut microbiota, cardio-metabolic profile, appetite and inflammatory markers.

NCT ID: NCT03284788 Completed - Obesity Clinical Trials

Wellness Achieved Through Changing Habits (The WATCH Study)

Start date: August 8, 2018
Phase: N/A
Study type: Interventional

The purpose of this pilot, feasibility study is to investigate the acceptability of an acceptance-based therapy healthy lifestyle intervention in adolescent girls with overweight/obesity.

NCT ID: NCT03283618 Completed - Obesity Clinical Trials

Implementation of Medical Weight Management by Telemedicine

Start date: November 16, 2015
Phase: N/A
Study type: Interventional

As the prevalence and associated healthcare costs of obesity continue to increase, the need for obesity treatments that contribute to weight loss maintenance are needed. Through the functionality of a smart device, telehealth can provide quality healthcare to individuals of different socioeconomic communities, expand healthcare access, as well as reduce overall healthcare costs. This research program will uncover the effects of a 12-week commercially available telehealth-based weight management program (inHealth Medical Services, Inc.) on body weight, blood pressure, and steps.