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Stress Disorders, Post-Traumatic clinical trials

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NCT ID: NCT05565352 Enrolling by invitation - Clinical trials for Major Depressive Disorder

Observation of Ketamine Treatment Safety and Tolerability in Adult Psychiatry Clinic Medical University of Gdańsk Inpatients

KetGD
Start date: September 1, 2022
Phase:
Study type: Observational

Adult Psychiatry Clinic Medical University of Gdańsk (MUG) is a healthcare facility that provides ketamine treatment to adult patients suffering from mental health conditions. The Clinic especially treats individuals suffering from treatment-resistant disorders, like - mood disorders, anxiety disorders, obsessive-compulsive and related disorders, trauma and stressor-related disorders, somatic symptom and related disorders, and dissociative disorders. Herein, this naturalistic observation aims to look at the safety and tolerability of ketamine treatment to further develop the understanding of ketamine in the use of psychiatry.

NCT ID: NCT05564663 Recruiting - Clinical trials for Alcohol Use Disorder

Testing a PTSD m-Health Intervention to Improve Alcohol Treatment Outcomes

Start date: October 6, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to learn whether a mobile health application (mHealth App) for posttraumatic stress disorder (PTSD) with brief support can help individuals who are in treatment for alcohol problems.

NCT ID: NCT05563805 Recruiting - Depression Clinical Trials

Exploring Virtual Reality Adventure Training Exergaming

V-RATE
Start date: September 7, 2022
Phase: N/A
Study type: Interventional

The current project aims to design and implement an 8-week Virtual Reality Adventure Therapy Exergaming (V-RATE) intervention focused on women veterans. A randomized controlled trial using a repeated measure design with a 1-month follow-up assessment will be employed to examine effects on physical and mental health outcomes.

NCT ID: NCT05562973 Withdrawn - Clinical trials for Post-Traumatic Stress Disorder

Safety and Tolerability of Psilocybin in Post-Traumatic Stress Disorder

Start date: January 2025
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, and potential efficacy of psilocybin-assisted psychotherapy to reduce post-traumatic stress disorder (PTSD) severity in a sample of individuals with PTSD.

NCT ID: NCT05560854 Completed - Clinical trials for Post Traumatic Stress Disorder

A Feasibility Study of Internet Delivered Prolonged Exposure

Start date: October 18, 2022
Phase: N/A
Study type: Interventional

The primary objective with this study is to investigate the feasibility and acceptability of ten weeks of internet delivered prolonged exposure delivered through a digital platform with therapist support. The secondary objective is to investigate preliminary effects of internet delivered prolonged exposure in terms of reducing symptoms of post-traumatic stress, depression and increase quality of life.

NCT ID: NCT05560113 Recruiting - Clinical trials for Post-Traumatic Stress Disorder

Disrupting Fear-based Memory Consolidation

Start date: November 28, 2022
Phase: N/A
Study type: Interventional

This project represents a unique collaborative opportunity to pursue the essential proof-of-principle demonstration that non-invasive interference of sensory cortical memory consolidation shortly after an emotional experience can attenuate the cued fear response and potentially reduce the risk of developing post-traumatic stress disorder (PTSD). If successful, the study results would anchor a potential advance in the treatment of patients after a traumatic event and seed future animal and clinical studies of emotional sensory cortical memory consolidation to reduce the prevalence and negative sequelae of PTSD.

NCT ID: NCT05555056 Recruiting - Depression Clinical Trials

Enhancing the Effectiveness of Cognitive Behavioral Therapy Using Non-invasive Brain Stimulation

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The purpose of the proposed study is to examine if a repeated treatment of High Definition Transcranial Direct Current Stimulation (HD-tDCS) can increase the functional connectivity between the left ventrolateral prefrontal cortex and posterior cingulate, which may further enhance the effects of cognitive behavioral therapy with mindfulness classes.

NCT ID: NCT05554094 Recruiting - PTSD Clinical Trials

Psilocybin for the Treatment of Veterans With Post-Traumatic Stress Disorder

Start date: January 1, 2023
Phase: Phase 2
Study type: Interventional

The primary aim of this study is to assess the safety and efficacy of psilocybin-assisted therapy in the treatment of post-traumatic stress disorder in United States military Veterans.

NCT ID: NCT05553249 Enrolling by invitation - Clinical trials for Post Traumatic Stress Disorder

Written Exposure Therapy for PTSD in a Virtual, Group-based Format

Start date: November 14, 2022
Phase:
Study type: Observational

The purpose of this study is to examine whether Written Exposure Therapy (WET) can be effectively delivered virtually and in a group format for the treatment of Post-Traumatic Stress Disorder in a military and police population. The objective of this study is to assess treatment feasibility and acceptability, drop out rates, changes in severity of trauma-related symptoms and symptoms of depression, quality of life, and the need for further trauma-focused treatment (TFT) for the the delivery of WET as a virtual, group based intervention.

NCT ID: NCT05550753 Completed - Clinical trials for Burnout, Professional

Better Together Physician Coaching to Mitigate Burnout in Male-Identifying Trainees

BTPC
Start date: January 2, 2023
Phase: N/A
Study type: Interventional

Better Together Physician Coaching ("Better Together", or "BT"), a 4-month, web-based positive psychology multimodal coaching program was built to decrease burnout in medical trainees. Here, the investigators seek to understand it's efficacy in male-identifying trainees at the University of Colorado - Aim 1: Implement Better Together in for male-identifying trainees in Graduate Medical Education at the University of Colorado. - Aim 2: Assess outcomes: primary: reduce burnout as measured by the Maslach Burnout Index (goal: 10% relative improvement), and secondary: self-compassion, imposter syndrome, flourishing and moral injury. - Aim 3: Advance the field of coaching in GME through innovation and dissemination of evidence-based approaches to GME trainee wellbeing.