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Stress Disorders, Post-Traumatic clinical trials

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NCT ID: NCT03770156 Not yet recruiting - Clinical trials for Post-Traumatic Stress Disorder

November 13, 2015 - Continuity of Care

Start date: January 1, 2019
Study type: Observational

On November 13th 2015, a terrorist attack killed 129 victims in Paris. An emergency crisis unit (CUMP) has been activated in Paris in the days following the attack and a subunit was in charge to answer to the phone calls of victims and their relatives. The purpose of this observational study is to document the evolution of psychiatric symptoms among subjects who called the CUMP and to collect information about the type of medical or non-medical care they were seeking for.

NCT ID: NCT03764033 Not yet recruiting - Moral Injury Clinical Trials

A Novel Posttraumatic Stress Disorder Treatment for Veterans With Moral Injury

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

The objective of this project is to test the efficacy of an individual treatment for post-traumatic stress disorder (PTSD) stemming from moral injury called Impact of Killing (IOK), compared to a present-centered therapy (PCT) control condition, and to determine the rehabilitative utility of IOK for Veterans with PTSD. The first aim is to test whether IOK can help improve psychosocial functioning for Veterans, as well as PTSD symptoms. The second aim is to determine whether IOK gains made by Veterans in treatment are durable, as measured by a six-month follow-up assessment. Veterans who kill in war are at increased risk for functional difficulties, PTSD, alcohol abuse, and suicide. Even after current PTSD psychotherapies, most Veterans continue to meet diagnostic criteria for PTSD, highlighting the need for expanding treatments for PTSD and functioning. IOK is a treatment that can be provided following existing PTSD treatments, filling a critical gap for Veterans with moral injury who continue to suffer from mental health symptoms and functional difficulties.

NCT ID: NCT03761732 Recruiting - Clinical trials for Post Traumatic Stress Disorder

Islamic Trauma Healing: Feasibility Study

Start date: October 15, 2018
Phase: N/A
Study type: Interventional

This study will examine the initial feasibility of a program called Islamic Trauma Healing by conducting a small feasibility study (N = 20) of Islamic Trauma Healing in Somalia on key targets of PTSD, depression, somatic symptoms, and quality of life. The hypothesis is that those in Islamic Trauma Healing will show a reduction of PTSD symptoms, depressive symptoms, and somatic symptoms and show improvement in quality of well-being. Feasibility will also be examined by examining at retention, satisfaction, and community feedback.

NCT ID: NCT03760601 Not yet recruiting - Clinical trials for Intrusive Memories of Trauma, Symptom of Post Traumatic Stress Disorder (Criterion B1)

A Brief Cognitive Intervention After Intrusive Memories of Trauma With Young Refugees: An Extension

Start date: December 4, 2018
Phase: N/A
Study type: Interventional

This research study is designed to investigate the use of a simple cognitive task (a memory cue and 10 minute time gap, followed by playing the computer game "Tetris") for decreasing the number of intrusive memories of trauma among young refugees and asylum seekers. The design is a single case experimental AB design with optional replication (ABAB). Participants will aim to complete a no-intervention phase ('A': baseline phase) of one week followed by a one-week intervention phase ('B'), including a one-session intervention with a researcher comprising the simple cognitive task, followed by instructions to continue to use the technique self-guided in the subsequent week. Follow ups are conducted after each week to monitor the occurrence of intrusive memories of trauma in a pen-and-paper diary. It is predicted that participants will report fewer intrusive memories during the intervention phase than during the preceding baseline phase.

NCT ID: NCT03759171 Completed - Depression Clinical Trials

Music-instruction Intervention for Treatment of Post-traumatic Stress Disorder

Start date: October 1, 2010
Phase: N/A
Study type: Interventional

The purpose of this study was to examine the feasibility and potential effectiveness of an active, music-instruction intervention in improving psychological health and social functioning among Veterans suffering from moderate to severe Post-traumatic Stress Disorder (PTSD).

NCT ID: NCT03758599 Recruiting - Anxiety Clinical Trials

Exercise in Anxiety and Posttraumatic Stress Disorders

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

Aim: Aerobic and resistance exercise showed anxiolytic effects in clinical populations. Climbing could further enhance self-efficacy. Aim of the study is to examine whether climbing exercise and aerobic exercise, compared to social contact control, reduces symptoms of disease in out-patients with anxiety disorder (AD) and post-traumatic stress disorder (PTSD). Further analyses are aiming to reveal differences between climbing - and aerobic exercise. Design: Randomized controlled clinical trial Participants: Thirty out-patients diagnosed with International Classification of Disease-Version 10 (ICD-10) (F40, F41, F43.1) for AD or PTSD. Intervention: Out-patients will be assigned randomly to a climbing exercise group (a), aerobic exercise group (Nordic walking) (b) or social contact control group (c). Measurements: Primary outcome is symptom severity in AD or Post Traumatic Stress Disorders. Further secondary outcomes are evaluated by psychological questionnaires assessing depression, worry symptoms, quality of life, self-efficacy and affective responses. Metabolites of neurotransmitters, immune-activation markers and anthropometric data will be additionally provided as secondary physiological outcomes. Duration: Intervention duration is four weeks with 2 x 75 min for every group (climbing exercise, aerobic exercise, social contact control). Measurement points are set at the beginning (t1), at the end of the intervention (t2) and 3 (t3) and 6 (t4) months follow-up.

NCT ID: NCT03757494 Recruiting - Clinical trials for PTSD, Post Traumatic Stress Disorder

Cranial Electrotherapy Stimulation in the Treatment of Posttraumatic Stress Disorder

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

This is a research study that will look at how well a treatment called Cranial Electrotherapy Stimulation (CES) works for patients who struggle with symptoms of Posttraumatic Stress Disorder. Cranial Electrotherapy Stimulation is delivered using a device called Alpha-Stim®. This is a safe, non-invasive treatment that applies a low-level pulsed electric current through the brain using clip-on electrodes attached to the earlobes. Cranial Electrotherapy Stimulation treats conditions such as physical pain, anxiety, and depression.

NCT ID: NCT03752918 Not yet recruiting - Clinical trials for Post Traumatic Stress Disorder

The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.

Start date: January 2, 2019
Phase: Phase 1
Study type: Interventional

This study aims to investigate the effects of MDMA on prefrontal and amygdala activation, and to explore the relationship between these MDMA-induced neural changes and the acute behavioral effects of the drug in patients with PTSD.

NCT ID: NCT03748121 Recruiting - Clinical trials for Posttraumatic Stress Disorder

Yoga/Pranayama for Posttraumatic Stress Disorder

Start date: February 20, 2018
Phase: N/A
Study type: Interventional

This study aims to investigate the effect of a pranayama focused yoga intervention on posttraumatic symptom severity in patients with posttraumatic stress disorder undergoing standard psychotherapy/cognitive-behavioral therapy (CBT). Therefore, short pranayama sessions of 5-10 minutes will be provided to the patients directly before each of standard CBT units, while the control group will get standard CBT alone. It should further be investigated, whether Pranayama can enhance the affective tolerance of patients with posttraumatic stress disorder towards the used exposure techniques of CBT.

NCT ID: NCT03747055 Recruiting - Depression Clinical Trials

Effectiveness of Group Focused Psychosocial Support for Adults Affected by Humanitarian Crises

Start date: November 25, 2018
Phase: N/A
Study type: Interventional

This is an effectiveness study of group problem management plus, a low-intensity psychological intervention, delivered in five sessions to adults affected by humanitarian crises. The current study will evaluate the effectiveness of Group Problem Management Plus (PM+).