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Stress Disorders, Post-Traumatic clinical trials

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NCT ID: NCT03960892 Enrolling by invitation - Depression Clinical Trials

Implementation of Group Problem Management Plus (PM+) in Adult Syrian Refugees in Turkey: RCT (STRENGTHS)

(STRENGTHS)
Start date: December 29, 2018
Phase: N/A
Study type: Interventional

To implement Group Problem Management Plus (PM+) in Syrian refugees with this RCT to evaluate feasibility, acceptability, effectiveness and cost-effectiveness of the culturally adapted Group PM+ intervention for adult Syrian refugees in Turkey.

NCT ID: NCT03960658 Recruiting - Clinical trials for Post-traumatic Stress Disorder

Ketamine and Prolonged Exposure in PTSD

Start date: April 3, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This study aims at investigating the effectiveness of the drug, Ketamine, in combination with Prolonged Exposure (PE) therapy for people suffering from PTSD. Participation in the study includes Ketamine infusions, which occur once a week for three weeks. PE therapy sessions will be scheduled one day after each infusion, and may continue up to 12 weeks. After completely therapy, there will be two monthly follow-up assessment visits.

NCT ID: NCT03954522 Not yet recruiting - Clinical trials for Post Traumatic Stress Disorder

The Visiting Child and His Family in ICU

ENVIFAR
Start date: June 1, 2019
Phase: N/A
Study type: Interventional

According to literature, it's difficult to evaluate the impact of the visit of the child in ICU. Currently, no recommendations are available regarding welcome and accompany children who visit their relative hospitalized in ICU. Collaboration between humanities and medical sciences brings to this question a complementary look. Majority of studies investigated the question of the impact of young child ICU visit in a unidirectional linear causality scheme visit = psychopathological impact. The visit of the child in ICU should not be considered as an isolated event whose objective characteristics would be alone vectors of trauma. Contrary, the child visit must be apprehended in relation to the quality of the supports on which the child can count. The investigators hypothesize that children can overcome the visit of a kin hospitalized in ICU if accompanying people can support the child and contain, before and after the visit, the emotions of the child.

NCT ID: NCT03950869 Recruiting - Clinical trials for Posttraumatic Stress Disorder

The Role of Expectations in the Development of Intrusive Memories

Start date: May 13, 2019
Phase: N/A
Study type: Interventional

In the experimental study, the well-established trauma film paradigm will be used to investigate the impact of expectations on the development of intrusive memories as a hallmark symptom of PTSD.

NCT ID: NCT03947099 Recruiting - Anxiety Disorders Clinical Trials

Ketamine Infusion Therapy for the Treatment of PTSD in Paramedics

Start date: May 2, 2019
Phase:
Study type: Observational

This is an observational study to assess the change in several psychological screening tools before and after a series of six ketamine infusions in paramedics who suffer from post traumatic stress disorder as a result of working in emergency medical services.

NCT ID: NCT03944447 Recruiting - Cancer Clinical Trials

Outcomes Mandate National Integration With Cannabis as Medicine

OMNI-Can
Start date: December 1, 2018
Phase:
Study type: Observational [Patient Registry]

This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.

NCT ID: NCT03936738 Not yet recruiting - Quality of Life Clinical Trials

Posttraumatic Stress Disorder and Quality of Life of Avalanche Survivors From 2014 to 2018, Based on the French North Alpine Avalanche Register: Risk Factor Analysis

ESPT Avalanche
Start date: May 1, 2019
Phase:
Study type: Observational

The aim of this study is to identify if an avalanche accident has a psychological impact on avalanche victims. The investigators hypothesize that being exposed to an avalanche could generate enough stress to develop posttraumatic stress symptoms or even more, an authentic posttraumatic stress disorder (PTSD). Additionally, the investigators think that such symptoms might lead to physical and psychological distress in daily life. Lastly, the investigators suppose that a serious traumatism, a complete and/or prolonged burial, the death of a family member or a closed friend could be a potential risk factors to develop PTSD symptoms in avalanche victims. To evaluate post traumatic stress symptoms and the quality of life of avalanche survivors, the investigators use the Impact of Event Scale - Revised and the Short Form 12. These two scales are included in a standardized questionnaire, which is submitted to avalanche victims during a phone call.

NCT ID: NCT03935035 Not yet recruiting - Clinical trials for Post Traumatic Stress Disorder

Online PTSD Treatment for Young People and Carers - Case Series

OPTYC
Start date: May 2, 2019
Phase: N/A
Study type: Interventional

Post Traumatic Stress Disorder (PTSD) is prevalent and impairing in children and young people. Effective face to face treatments exist, including Cognitive Therapy for PTSD (CT-PTSD), developed by the researchers' group. However, few young people access effective treatments. The researchers are therefore developing a website and smart-phone App that will improve accessibility of this treatment by allowing trained therapists to deliver CT-PTSD over the internet (iCT) to young people (12-17 years old) with PTSD. This study aims to provide an initial evaluation of iCT. This will be done by running an uncontrolled case series with 6 young people. The objectives of the case series are to: to gauge acceptability of the programme to young people, carers, and therapists; to measure adherence to the programme; to test the battery of measures for acceptability; and to obtain estimates of clinical change.

NCT ID: NCT03934658 Not yet recruiting - Clinical trials for PostTraumatic Stress Disorder

Remote Study of NightWare for PTSD With Nightmares

NWVRCT
Start date: May 15, 2019
Phase: N/A
Study type: Interventional

This study will provide measures of safety and efficacy of the NightWare digital therapeutic system (iPhone + Apple watch + proprietary application) for the treatment of nightmare disorder associated with post-traumatic stress disorder (PTSD)-related sleep disturbance and the impact of improved sleep with the NightWare digital therapeutic system. The investigators hypothesize that the NightWare digital therapeutic system will significantly improve sleep quality in participants with PTSD-Related nightmares and poor sleep quality.

NCT ID: NCT03933059 Recruiting - Clinical trials for Stress Disorders, Post-Traumatic

Suicide and Trauma Reduction Initiative Among VEterans

STRIVE
Start date: March 21, 2019
Phase: N/A
Study type: Interventional

The present study is a pragmatic clinical trial that will examine the effectiveness of Cognitive Processing Therapy (CPT) in reducing PTSD symptom severity, depression symptoms, and suicidal thoughts among military personnel and veterans with PTSD when delivered in three different formats: (1)12 sessions delivered once per week in an office/clinic setting; (2) 12 sessions delivered once per day in an office/clinic setting; and (3) 12 sessions delivered once per day in a recreational setting.