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Stress Disorders, Post-Traumatic clinical trials

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NCT ID: NCT06370559 Completed - Anxiety Disorders Clinical Trials

Relationship Between Repetitive Negative Thinking and CBT Outcomes

Start date: January 1, 2022
Phase:
Study type: Observational

The goal of this observational study is to learn about the role of repetitive negative thinking (measured by the RTQ) in adult populations from an anxiety disorders and trauma clinic. The main questions it aims to answer are: - Whether the repetitive negative thinking can be used to predict i. initial symptom severity, and ii. therapy outcome (measured by change in scores on disorder specific measures). - Whether change in RTQ mediates change in outcome Participants are sent weekly questionnaires that measure their progress. Within these questionnaires are the RTQ and other disorder-specific measures that we will be analysing. Researchers may also compare clients with different disorders to see the accuracy the RTQ can predict treatment outcomes for each disorder.

NCT ID: NCT06368999 Completed - Clinical trials for Stress Disorders, Post-Traumatic

Neurophysiological and Neuropsychological Evalution in Healthcare Workers

EEGCOV
Start date: May 27, 2020
Phase: N/A
Study type: Interventional

The goal of this observational study is to compare in participant population the effect of stress condition on cerebral EEG activity Participants will do an 8 minutes EEG registration. Researchers will compare EEG activity of heathcare workers.

NCT ID: NCT06207916 Completed - PTSD Clinical Trials

International Survey of Childbirth-Related Trauma - Swedish Part

SwIntersect
Start date: September 1, 2021
Phase:
Study type: Observational

The goal of this cross-sectional observational study is to analyze childbirth-related PTSD, traumatic birth experiences and stress symptoms postpartum. The main questions it aims to answer are: - What is the prevalence of traumatic birth experiences, PTSD and stress symptoms in a Swedish postnatal sample? - What are the risk factors for postnatal mental ill-health? Additional goals are to make cross-cultural translations of the instruments City BiTS and Birth Satisfaction Scale - Revised. Participants will answer an online surveys including several instruments measuring postnatal stress and mental ill-health.

NCT ID: NCT06110702 Completed - Clinical trials for Obsessive-Compulsive Disorder

Effects of an EMDR Intervention on Traumatic and Obsessive Symptoms

MDL
Start date: October 10, 2021
Phase: N/A
Study type: Interventional

The Eye Movement Desensitization and Reprocessing Protocol (EMDR) was first developed by Francine Shapiro in 1987 and can be adapted for online and in presence administration. The aim of this study is to assess if a EMDR program (administered both online and in presence, depending on different conditions of patients) may help people recruited from general population suffering from COVID19 second (November 2021 to February 2022) and third (March 2022 to May 2022) quarantine in improving post-traumatic stress (PTSD) and obsessive-compulsive-related (OCD) symptoms, as well as disgust, guilt, shame and their subjective unit of distress (SUD) and validity of cognition (VoC) levels.

NCT ID: NCT06073964 Completed - Clinical trials for Post-Traumatic Stress Disorder

GBV, Primary Trauma & Trauma Resilience & Understanding Self-help Therapy Utilization in Uganda

GBV
Start date: November 23, 2022
Phase: N/A
Study type: Interventional

The goal of this community-based interventional study was to determine the effectiveness of the 'Trauma Resilience & Understanding Self-help Therapy' (TRUST) in managing domestic violence & primary trauma among formerly Internally Displaced Persons (fIDPs) in northern Uganda. The main questions it aimed to answer were: - What was the level of utilization and short-term effects of the TRUST intervention on the experiences of domestic violence and high levels of primary trauma among fIDPs living in northern Uganda who would have been using TRUST within their communities after completing the training in the community-based TRUST utilization? - What were the clinical indications of the TRUST intervention and psychological operators among fIDPs living in northern Uganda who would have been using TRUST within their communities to manage their experiences of domestic violence and high levels of primary trauma? Participants found to have experienced domestic violence in the last one year and were having high levels of primary trauma were randomly assigned to the intervention group that was trained in the utilization of the TRUST within their communities and then followed up for 12 weeks (TRUST group). The investigators then compared the results obtained from the TRUST group with those attained from an age and gender cross-matched control group of fIDPs who were not trained in the utilization of the TRUST within their communities (Control group). This was done to see if the community-based utilization of the TRUST intervention changed the levels of primary trauma & experiences of domestic violence among its users (TRUST group) when compared to the non-users (Control group).

NCT ID: NCT06016673 Completed - PTSD Clinical Trials

Testing a Causal Model of Cognitive Control Deficits in Posttraumatic Stress Disorder (PTSD)

Start date: September 13, 2023
Phase: N/A
Study type: Interventional

Testing a Causal Model of Cognitive Control Deficits in Posttraumatic Stress Disorder (PTSD)

NCT ID: NCT05993468 Completed - Clinical trials for Complex Post-Traumatic Stress Disorder

A Pilot Study of a Trauma-Sensitive Mindfulness and Compassion Intervention

Start date: January 1, 2019
Phase:
Study type: Observational

This mixed-methods pilot study aim to assess the changes in symptoms of post-traumatic stress disorder (PTSD), complex post-traumatic stress disorder (CPTSD), dissociative symptoms, self-critique, and self-compassion following participation in a 16-week trauma-sensitive mindfulness and compassion (TMC) intervention. Adverse experiences of participation are also explored explicitly.

NCT ID: NCT05924399 Completed - Clinical trials for Post-traumatic Stress Disorder

PTSD Affect Labeling Study

Start date: August 5, 2014
Phase: N/A
Study type: Interventional

The overall goal of this study is to use fMRI and psychophysiological measures to investigate a novel strategy involving "Affect Labeling" for improving emotion regulation in PTSD that could lead to a new treatment regimen for PTSD. Our project has two specific aims. First, the investigators aim to identify a novel neural target for possible PTSD intervention by verifying that RVLPFC-based inhibitory processing is impaired in PTSD. Second, the investigators will examine whether repeated practice with a simple cognitive-emotional task that requires inhibitory processing, namely, affect labeling, can strengthen the RVLPFC's ability to down-regulate emotional responses and physiological reactivity in PTSD and thereby form the basis of a novel treatment strategy to be developed in future studies. Secondary objectives are to examine the extent to which RVLPFC-based inhibitory impairments in PTSD are specific to trauma-relevant emotional processing (i.e., trauma-related distress) or extend to other types of inhibitory regulation in general, which would have implications for the future study of inhibitory-enhancement-based interventions for PTSD.

NCT ID: NCT05895318 Completed - Clinical trials for Post Traumatic Stress Disorder

Perceptions of MDMA-Assisted Therapy Among Veterans With PTSD

PMATAVP
Start date: August 8, 2022
Phase:
Study type: Observational

The goal of this exploratory, mixed-method design study is to gather qualitative and quantitative data obtained through interviews and questionnaires with veterans who are currently enrolled at the VA for healthcare. The main question this study aims to answer is: How do veterans diagnosed with PTSD and enrolled for care at the VA understand MDMA-assisted therapy for PTSD? Using a story-completion approach, participants will be provided with a brief story starter involving a fictitious character and scenario and asking them to complete the story. Few contextual details will be offered about the character. In responding to ambiguous cues, participants are thought to project their conscious and subconscious perceptions about the phenomenon in question onto the story, a useful method for exploring stigmatized topics. The purpose of this exercise is to ascertain the participants attitudes and perceptions regarding MDMA-Assisted Therapy.

NCT ID: NCT05881174 Completed - PTSD Clinical Trials

Rapid Acupuncture Treatment for Post-Traumatic Stress Disorder

Start date: November 24, 2020
Phase: N/A
Study type: Interventional

The summary of this research study is to test the effectiveness of a rapid "rescue" acupuncture technique as a non-pharmacologic alternative treatment for the reduction of post-traumatic stress disorder (PTSD) symptoms in affected individuals as a means to improve warfighter health and enable a more rapid return to duty, especially in austere environments. Patients will receive acupuncture as a research-related course of treatment for PTSD. The PCL-5 questionnaire will be used to assess the presence and severity of PTSD symptoms. A PCL-5 questionnaire will be administered at the beginning of the first treatment of "rescue" acupuncture and after the last treatment. Following the acupuncture treatment, a PCL-5 questionnaire will be initiated at the beginning of the first week of treatment and the end of the second week of treatment at the participating Mental Health Clinic (pMHC).