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Stress Disorders, Post-Traumatic clinical trials

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NCT ID: NCT03979040 Completed - Clinical trials for Major Depressive Disorder

Comparing Group Therapies for Veterans With Depression and PTSD

Start date: February 3, 2021
Phase: N/A
Study type: Interventional

Cognitive behavioral therapy (CBT) is a brief, efficient, and effective psychotherapy for individuals with depressive and PTSD. However, CBT is largely underutilized within Veteran Affairs Medical Centers (VAMCs) due to the cost and burden of trainings necessary to deliver the large number of CBT protocols. Transdiagnostic Behavior Therapy (TBT), in contrast, is specifically designed to address numerous distinct disorders within a single protocol. The transdiagnostic approach of TBT has the potential to dramatically improve the accessibility of CBT within VAMCs and therefore improve clinical outcomes of Veterans. The proposed research seeks to evaluate the efficacy of a group version of TBT (G-TBT) by assessing clinical outcomes and quality of life in VAMC patients with major depressive disorder and PTSD throughout the course of treatment and in comparison to two existing group disorder-specific therapies (G-DST), CBT for Depression and Cognitive Processing Therapy for PTSD.

NCT ID: NCT03969589 Completed - Clinical trials for Stress Disorders, Post-Traumatic

Reproductive Life Planning for Women With Mental Illness

RLP-MH
Start date: July 1, 2019
Phase: N/A
Study type: Interventional

Women represent the fastest growing population within the VHA. Many are of reproductive age and experience mental health concerns. Women with mental illness are at greater risk for unplanned pregnancy and poor pregnancy outcomes due to factors related to mental health and mental health treatment. Similarly, mental health concerns (e.g., impact of pregnancy on mental illness, psychiatric medications and pregnancy) can affect reproductive life goals and plans. Reproductive life planning (RLP) interventions that include considerations and concerns women Veterans with mental illness face are needed. The investigators adapted existing RLP materials to create an interactive, individualized, client-centered RLP intervention designed to help women Veterans with mental illness develop a mental health-informed reproductive life plan and reproductive life goals (RLP-MH). The current study aims to determine if the RLP-MH intervention is feasible and acceptable to women Veterans and if it increases engagement in behaviors to address RLP goals.

NCT ID: NCT03960892 Completed - Depression Clinical Trials

Implementation of Group Problem Management Plus (PM+) in Adult Syrian Refugees in Turkey: RCT (STRENGTHS)

(STRENGTHS)
Start date: December 29, 2018
Phase: N/A
Study type: Interventional

To implement Group Problem Management Plus (PM+) in Syrian refugees with this RCT to evaluate feasibility, acceptability, effectiveness and cost-effectiveness of the culturally adapted Group PM+ intervention for adult Syrian refugees in Turkey.

NCT ID: NCT03960658 Completed - Clinical trials for Post-traumatic Stress Disorder

Ketamine and Prolonged Exposure in PTSD

Start date: April 3, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This study aims at investigating the effectiveness of the drug, Ketamine, in combination with Prolonged Exposure (PE) therapy for people suffering from PTSD. Participation in the study includes Ketamine infusions, which occur once a week for three weeks. PE therapy sessions will be scheduled one day after each infusion, and may continue up to 12 weeks. After completely therapy, there will be two monthly follow-up assessment visits.

NCT ID: NCT03950869 Completed - Clinical trials for Posttraumatic Stress Disorder

The Role of Expectations in the Development of Intrusive Memories

Start date: May 31, 2019
Phase: N/A
Study type: Interventional

In the experimental study, the well-established trauma film paradigm will be used to investigate the impact of expectations on the development of intrusive memories as a hallmark symptom of PTSD.

NCT ID: NCT03947099 Completed - Anxiety Disorders Clinical Trials

Ketamine Infusion Therapy for the Treatment of PTSD in Paramedics

Start date: May 2, 2019
Phase:
Study type: Observational

This is an observational study to assess the change in several psychological screening tools before and after a series of six ketamine infusions in paramedics who suffer from post traumatic stress disorder as a result of working in emergency medical services.

NCT ID: NCT03936738 Completed - Quality of Life Clinical Trials

Posttraumatic Stress Disorder and Quality of Life of Avalanche Survivors From 2014 to 2018, Based on the French North Alpine Avalanche Register

ESPTAvalanche
Start date: May 1, 2019
Phase:
Study type: Observational

The aim of this study is to identify if an avalanche accident has a psychological impact on avalanche victims. The investigators hypothesize that being exposed to an avalanche could generate enough stress to develop posttraumatic stress symptoms or even more, an authentic posttraumatic stress disorder (PTSD). Additionally, the investigators think that such symptoms might lead to physical and psychological distress in daily life. Lastly, the investigators suppose that a serious traumatism, a complete and/or prolonged burial, the death of a family member or a closed friend could be a potential risk factors to develop PTSD symptoms in avalanche victims. To evaluate post traumatic stress symptoms and the quality of life of avalanche survivors, the investigators use the Impact of Event Scale - Revised and the Short Form 12. These two scales are included in a standardized questionnaire, which is submitted to avalanche victims during a phone call.

NCT ID: NCT03934658 Completed - Clinical trials for PostTraumatic Stress Disorder

Remote Study of NightWare for PTSD With Nightmares

NWVRCT
Start date: May 21, 2019
Phase: N/A
Study type: Interventional

This study will provide measures of safety and efficacy of the NightWare digital therapeutic system (iPhone + Apple watch + proprietary application) for the treatment of nightmare disorder associated with post-traumatic stress disorder (PTSD)-related sleep disturbance and the impact of improved sleep with the NightWare digital therapeutic system. The investigators hypothesize that the NightWare digital therapeutic system will significantly improve sleep quality in participants with PTSD-Related nightmares and poor sleep quality.

NCT ID: NCT03933059 Completed - Clinical trials for Stress Disorders, Post-Traumatic

Suicide and Trauma Reduction Initiative Among VEterans

STRIVE
Start date: March 21, 2019
Phase: N/A
Study type: Interventional

The present study is a pragmatic clinical trial that will examine the effectiveness of Cognitive Processing Therapy (CPT) in reducing PTSD symptom severity, depression symptoms, and suicidal thoughts among military personnel and veterans with PTSD when delivered in three different formats: (1)12 sessions delivered once per week in an office/clinic setting; (2) 12 sessions delivered once per day in an office/clinic setting; and (3) 12 sessions delivered once per day in a recreational setting.

NCT ID: NCT03930966 Completed - General Anaesthesia Clinical Trials

Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome

DIStress-AG
Start date: April 9, 2019
Phase: N/A
Study type: Interventional

Patients will be selected after studying clinical records.Patients who had general anesthesia due to an injury related to severe trauma within 6 to 12 months prior to inclusion will be included. Three self-survey will be completed by the patient: PDEQ, PCL-5 and a demographic questionnaire. According to the PDEQ and PCL-5 scores, an association between a peri-traumatic dissociation state and a post-traumatic stress disorder can be established.