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Quality of Life clinical trials

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NCT ID: NCT03583398 Completed - Quality of Life Clinical Trials

Health-related QoL Following TAVI TAo, TAVI TF and AVR

Start date: January 2015
Phase:
Study type: Observational

The aim of the study was to evaluate short- and long-term changes in QoL in patients undergoing TAVI and to assess differences in patient QoL when using the TAVI TAo approach compared with the transfemoral approach (TAVI TF) and surgical aortic valve replacement (SAVR).

NCT ID: NCT03581253 Recruiting - Quality of Life Clinical Trials

Validation of a French-language Version of Quality of Life Questionnaires in Patients With Peripheral Facial Palsy

PFQDV
Start date: December 15, 2017
Phase: N/A
Study type: Interventional

Facial palsy is a serious and disabling disease whose drudgery and sensation are probably underestimated. Psychological, social and economic issues have major impacts although vital prognosis is not engaged in this pathology. Facial palsy remains a personal drama for patient. Consequences may take the form of: aesthetic deformation, modification of body image, with socio-professional consequences. Beside unsightly facial aspects, weakness of facial muscles can cause troubles in eating, drinking, talking, communicating personal emotions and communication. Facial palsy impacts patients' quality of life (QOL) and affects mental health. This wide multidimensional concept usually includes self-measures of physical and mental health. QOL is evaluated with general and specific scales. General scales allow to compare QOL of different diseases, when specific scales focus on one disease and consider all aspects related to this disease and therefore are more appropriate and sensitive in dimensions related to patient disease and health. "Facial disability Index" (FDi) and "Facial Clinimetric Evaluation" (FaCE) are the most used validated questionnaires to assess QOL of patients suffering from peripheral facial palsy (PFP). There is no existing validated questionnaire or scale in French version despite many French studies on PFP available. Using these questionnaires in French language requires translation and strict approval of the new language version. The aim of the study is to translate and validate French versions of specific scales of QOL in peripheral facial palsy patients: FDI and FaCE. Secondary objective is to evaluate QOL of patients depending on PFP etiology. Translation process will be done respecting internationally recognized rules. A pilot study will be performed on 5 physicians and 5 patients in order to validate the questionnaires translations. French versions obtained will be used for their validation on 80 patients suffering from PFP. Cronbach's alpha will be estimated to check internal consistency of FDI and FaCE scales. Test re-test reliability will be calculated with inter-class correlation, reiterating questionnaires one week later. Scores of FDI and FaCE scales will be compared to other clinical evaluation scales, estimating correlation coefficient. Social function of FDI and FaCE scales will be compared with general scale SF-36 scores, estimating a correlation coefficient.

NCT ID: NCT03580551 Not yet recruiting - Quality of Life Clinical Trials

Older Veterans EmpoweRed To Use Regular Exercise (OVERTURE) II

OVERTURE
Start date: August 1, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the practicality of a short-term (8-weeks), home-based digital versatile disc (DVD) chair exercise program among 40 sedentary older Black/African American and White/Caucasian veterans with three or more chronic health conditions, such as type 2 diabetes, hypertension, and osteoarthritis.

NCT ID: NCT03579342 Recruiting - Quality of Life Clinical Trials

App-technology to Improve Healthy Lifestyle Behaviors Among Working Adults

Start date: April 16, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate if modern technology such as smartphone applications can be used to facilitate lifestyle changes and thereby improve health-related quality of life in gainfully employed persons in the general population in Stockholm, Sweden. The hypothesis is that at follow-up, the intervention group that use the new application will have improved health-related quality of life and other lifestyle habits including diet, physical activity and sleep, as well as biomarkers, compared to a control group.

NCT ID: NCT03578900 Completed - Quality of Life Clinical Trials

Quality of Life and Sjögren Syndrome

Start date: January 1, 2013
Phase: Phase 4
Study type: Interventional

The aims of this study are: To compare salivary pH changes and stimulation efficacy of two different Gustatory Stimulants of Salivation (GSSS) in patients with Primary Sjögren Syndrome (PSS); To evaluate Primary Sjögren syndrome (PSS) impact and gustatory stimulants of salivary secretion (GSSS) on oral health related quality of life measured by a Portuguese version of Oral Health Impact Profile-14 (OHIP-14) and specific Xerostomia assessment questionnaires. The Products to be used are the Xeros® Dentaid system and a citric based mouthwash.

NCT ID: NCT03577392 Not yet recruiting - Quality of Life Clinical Trials

Recombinant Human Endostatin in Combination With XELOX Therapy in Patient With Advanced Colorectal Cancer.

EXECC
Start date: July 1, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

To study safety and efficacy of intravenous pump of recombinant human endostatin combined with XELOX-treated and also investigate the potential value of CECs level for the prediction of PD and outcomes in patients with advanced colorectal cancer.

NCT ID: NCT03576209 Not yet recruiting - Quality of Life Clinical Trials

Effects of a Walking Intervention on Health Outcomes in Older Adults

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Medical condition or disease under investigation : Quantitative and qualitative aspects of sleep, quality of life, functional ability and well-being in older adults (>55years) Purpose of clinical trial : To study the prospective effects of a walking intervention (Health promotion program) on quantitative and qualitative aspects of sleep, quality of life, functional ability and well-being in older adults. Primary objective : Measure the effects of walking intervention on quantitative and qualitative aspects of sleep Secondary objective (s) : Measure the effects of walking intervention on physical activity, quality of life, functional ability and well-being Social identity and leadership, social support and motivation Trial Design : Intervention study : controlled before-and-after study Sample Size : total sample size : 400 participants Summary of eligibility criteria : Older adults aged above 55years Included in intervention group : adults who are participating in the health promotion program 'Lekker Actief', organized by OKRA Included in control group : waitlist controls of controls (adults, members of OKRA, not participating in the health promotion program 'Lekker Actief') Maximum duration of treatment of a Subject : - Start of Health promotion program 'Lekker Actief' : September 2018 - Measurements with accelerometers will start prior to the Health promotion program 'Lekker Actief' : July 2018 - End of Health promotion program 'Lekker Actief' : December 2018 - Duration of Health promotion program 'Lekker Actief': 12 weeks - Follow up measurements : October-December 2019 - Maximal duration : July 2018-December 2019

NCT ID: NCT03570788 Active, not recruiting - Quality of Life Clinical Trials

HRQoL Among Patients Amputated Due to Peripheral Arterial Disease

Start date: September 12, 2014
Phase:
Study type: Observational

A prospective cohort study over the prosthetic use among patients amputated after vascular disease and the impact of their HRQoL.

NCT ID: NCT03569982 Not yet recruiting - Quality of Life Clinical Trials

Integrative Care and Acupuncture in MOHS Surgery

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

MOHS method is an effective surgical technique to remove skin cancerous tumors in the head-neck area. Patients undergoing MOHS surgery are struggled with emotional stress during the day of surgery, due to fear of significant damage to the body's image and anxiety about the need for repeated surgeries. In this study we will examine the effect of integrative medicine (including acupuncture, touch/manual, and breathing/relaxation modalities) on the reduction of anxiety and pain in patients undergoing MOHS surgery.

NCT ID: NCT03568110 Not yet recruiting - Gastric Cancer Clinical Trials

Frailty and Postoperative Outcomes After Gastric Cancer Surgery

TOREGA
Start date: January 2019
Phase:
Study type: Observational [Patient Registry]

Background. Gastric cancer is an important health care problem even though treatment advances, and it is diagnosed mainly in elderly. Surgery is the main treatment for gastric cancer and is associated with a high rate of postoperative complications and mortality, even higher in older patients. Chronological age seems not to be the main factor influencing the worse outcome of older patients, comorbidities and frailty have also been taken into account recently. Methods. Participation in the study will be offered to all centers that are currently part of the Spanish EURECCA (EUropean REgistry of Cancer CAre) Esophagogastric Cancer Registry. The impact of the frailty on different outcome variables will be evaluated. The main outcome variable will be 90-day mortality after the intervention. Health-Related Quality of Life (HRQoL) will also be evaluated. Objective. The objective of the study is to value the impact of frailty on gastric cancer surgery outcomes therein the Spanish EURECCA Esophagogastric Cancer Registry.