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General Anaesthesia clinical trials

View clinical trials related to General Anaesthesia.

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NCT ID: NCT05789992 Completed - General Anaesthesia Clinical Trials

Evaluation of Equivalent Minimum Alveolar Concentration (eMAC) During Propofol/Remifentanil Anesthesia

eMAC
Start date: April 3, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to verify the accuracy of eMAC compared to Bispectral Index (BIS) for depth and nociceptive stimulation monitoring of anesthesia during general anesthesia.

NCT ID: NCT05681611 Completed - Breast Cancer Clinical Trials

Effect of Rocuronium on BIS Values

Start date: March 3, 2023
Phase:
Study type: Observational

Aim of this trial is to define if Trend of Four (TOF) values after a bolus of rocuronium is correlated with Bispectral Index BIS values during standard general anaesthesia for breast surgery.

NCT ID: NCT05107167 Completed - Muscle Weakness Clinical Trials

Electromagnetic Stimulation of the Phrenic Nerve of Intubated Patients With Obesity

STIMIT-IA
Start date: December 14, 2021
Phase: N/A
Study type: Interventional

Ventilator-induced diaphragmatic dysfunction is a common issue in critically ill patients. Muscle stimulation has shown to have beneficial effects in muscle groups on the extremities. A non-invasive way to stimulate the diaphragm would be the electromagnetic stimulation but it is currently unclear if that is feasible. In this proof-of-concept trial the primary aim is to show that it is possible to induce a diaphragmatic contraction leading to an inspiration with a sufficient tidal volume via an external electromagnetic stimulation of the phrenic nerve in obese patients.

NCT ID: NCT04946110 Completed - Muscle Weakness Clinical Trials

Electromagnetic Stimulation of the Phrenic Nerve of Intubated Patients

STIMIT-I
Start date: July 13, 2021
Phase: N/A
Study type: Interventional

Ventilator-induced diaphragmatic dysfunction is a common issue in critically ill patients. Muscle stimulation has shown to have beneficial effects in muscle groups on the extremities. A non-invasive way to stimulate the diaphragm would be the electromagnetic stimulation but it is currently unclear if that is feasible. In this proof-of-concept trial the primary aim is to show that it is possible to induce a diaphragmatic contraction leading to an inspiration with a sufficient tidal volume via an external electromagnetic stimulation of the phrenic nerve.

NCT ID: NCT04771962 Completed - General Anaesthesia Clinical Trials

Comparison of the Anaesthetic Gases in Maintainance of General Anaesthesia in Paediatrics

Start date: January 1, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Desflurane and Sevoflurane are one of the modern inhalational anaesthetic agents currently in use in anaesthetic practice. The properties of desflurane that has low blood gas solubility coefficient of 0.47 compared to sevoflurane (0.68) made it more advantageous when used with supraglottic airway in maintaining general anaesthesia in paediatrics . It ensures rapid onset and offset of anaesthesia. Rapid recovery profiles especially among pediatric populations is to ensure less complications associated with prolonged recovery of anaesthesia upon emergence from anaesthesia. Nevertherless, desflurane has its drawback which is it can cause airway irritability related to its pungency. Hence, it is not used as an induction anaesthetic agent in paediatrics. This study was done to evaluate the effectiveness of desflurane in comparison to sevoflurane in maintaining spontaneous general anaesthesia in paediatrics population using Ambu AuraGain .

NCT ID: NCT04760912 Enrolling by invitation - Muscle Weakness Clinical Trials

General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery

Start date: April 1, 2020
Phase: N/A
Study type: Interventional

Neuromuscular blocking agents are often used during general anesthesia. Also, general anesthesia may be performed without use of neuromuscular blocking agents. Avoiding neuromuscular relaxation enables better muscle strength recovery.

NCT ID: NCT04215302 Completed - General Anaesthesia Clinical Trials

Prediction Accuracy for Langeal Mask Unique TM Size in Pediatric Patient

Start date: September 17, 2019
Phase:
Study type: Observational

the study aimed to know the accuracy for laryngeal mask unique TM size to Malay pediatric race according to weight measurement recommended by manufacturer

NCT ID: NCT04125121 Completed - Healthy Volunteers Clinical Trials

Neuroplasticity Induced by General Anaesthesia

DANA1
Start date: September 26, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to use magnetic resonance imaging to explore and compare possible de novo neuroplastic changes induced by the isolated effects of the hypnotic agents sevoflurane and propofol, respectively. In addition, to explore possible associations between neuroplastic changes and clinical and/or biochemical outcomes. It is a randomised, cross-over, single blinded clinical study. N = 30. Female:male ratio 1:1.

NCT ID: NCT03930966 Completed - General Anaesthesia Clinical Trials

Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome

DIStress-AG
Start date: April 9, 2019
Phase: N/A
Study type: Interventional

Patients will be selected after studying clinical records.Patients who had general anesthesia due to an injury related to severe trauma within 6 to 12 months prior to inclusion will be included. Three self-survey will be completed by the patient: PDEQ, PCL-5 and a demographic questionnaire. According to the PDEQ and PCL-5 scores, an association between a peri-traumatic dissociation state and a post-traumatic stress disorder can be established.

NCT ID: NCT03682198 Completed - Neurosurgery Clinical Trials

Neuro-Ox 2018: Assessment of Cerebral Oxygenation Under Three Clinically Relevant Conditions

Start date: September 24, 2018
Phase: N/A
Study type: Interventional

This is a prospective observational study, consisting of 3 substudies carried out during elective neurosurgery under general anaesthesia. Each participant will take part in all 3 substudies. First, the capability of Near Infra Red Spectroscopy (NIRS) to measure the brain oxygenation is examined. A NIRS-electrode is placed on forehead skin, on the skull, and on dura. Secondly, a small dose of Phenylephrine is given, and the brain oxygenation is measured by a Clark-electrode and a NIRS-electrode, to see how Phenylephrine affects these measurements. In the third substudy, the brain oxygenations' (NIRS and Licox) response to an inspired oxygen fraction of 0.30 vs. 0.80 is investigated.