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Recurrent Small-cell Lung Cancer (SCLC) clinical trials

View clinical trials related to Recurrent Small-cell Lung Cancer (SCLC).

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NCT ID: NCT00698516 Completed - Clinical trials for Lung Cancer, Small Cell

Study of Oral Topotecan With Bevacizumab for Recurrent Small Cell Lung Cancer

Start date: July 2008
Phase: Phase 2
Study type: Interventional

Combination of Hycamtin (topotecan) and Avastin (bevacizumab) could allow killing of both endothelial and neoplastic cells. We postulate that addition of bevacizumab to topotecan will increase delivery of topotecan to tumor cells and may enhance activity of topotecan in patients with previously treated small cell lung cancer and improve progression free survival.